|Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis|
RF Schwarz, CKY Ng, SL Cooke, S Newman, J Temple, AM Piskorz, ...
PLoS Med 12 (2), e1001789, 2015
|Independence of Repressive Histone Marks and Chromatin Compaction during Senescent Heterochromatic Layer Formation|
T Chandra, K Kirschner, JY Thuret, BD Pope, T Ryba, S Newman, ...
Molecular Cell, 2012
|Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells.|
AS Little, K Balmanno, MJ Sale, S Newman, JR Dry, M Hampson, ...
Science signaling 4 (166), ra17, 2011
|Aberrant chromosome morphology in human cells defective for Holliday junction resolution|
T Wechsler, S Newman, SC West
Nature 471 (7340), 642-646, 2011
|Estimation of rearrangement phylogeny for cancer genomes|
CD Greenman, ED Pleasance, S Newman, F Yang, B Fu, S Nik-Zainal, ...
Genome research, 2011
|Deregulation of DUX4 and ERG in acute lymphoblastic leukemia|
J Zhang, K McCastlain, H Yoshihara, B Xu, Y Chang, ML Churchman, ...
Nature genetics 48 (12), 1481-1489, 2016
|Next-generation sequencing of duplication CNVs reveals that most are tandem and some create fusion genes at breakpoints|
S Newman, KE Hermetz, B Weckselblatt, MK Rudd
The American Journal of Human Genetics 96 (2), 208-220, 2015
|The NRG1 gene is frequently silenced by methylation in breast cancers and is a strong candidate for the 8p tumour suppressor gene|
YL Chua, Y Ito, JCM Pole, S Newman, SF Chin, RC Stein, IO Ellis, ...
Oncogene 28 (46), 4041-4052, 2009
|The role of tandem duplicator phenotype in tumour evolution in high‐grade serous ovarian cancer|
CKY Ng, SL Cooke, K Howe, S Newman, J Xian, J Temple, EM Batty, ...
The Journal of Pathology, 2011
|The genetic basis and cell of origin of mixed phenotype acute leukaemia|
TB Alexander, Z Gu, I Iacobucci, K Dickerson, JK Choi, B Xu, ...
Nature 562 (7727), 373-379, 2018
|PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia|
Z Gu, ML Churchman, KG Roberts, I Moore, X Zhou, J Nakitandwe, ...
Nature genetics 51 (2), 296-307, 2019
|Large duplications at reciprocal translocation breakpoints that might be the counterpart of large deletions and could arise from stalled replication bubbles|
KD Howarth, JCM Pole, JC Beavis, EM Batty, S Newman, GR Bignell, ...
Genome research 21 (4), 525-534, 2011
|Large inverted duplications in the human genome form via a fold-back mechanism|
KE Hermetz, S Newman, KN Conneely, CL Martin, BC Ballif, LG Shaffer, ...
PLoS genetics 10 (1), 2014
|Clinical validation and implementation of a targeted next-generation sequencing assay to detect somatic variants in non-small cell lung, melanoma, and gastrointestinal malignancies|
KE Fisher, L Zhang, J Wang, GH Smith, S Newman, TM Schneider, ...
The Journal of Molecular Diagnostics 18 (2), 299-315, 2016
|Heregulin and HER3 are prognostic biomarkers in oropharyngeal squamous cell carcinoma|
G Qian, N Jiang, D Wang, S Newman, S Kim, Z Chen, G Garcia, ...
Cancer 121 (20), 3600-3611, 2015
|Analysis of error profiles in deep next-generation sequencing data|
X Ma, Y Shao, L Tian, DA Flasch, HL Mulder, MN Edmonson, Y Liu, ...
Genome biology 20 (1), 50, 2019
|Clinical cancer genomic profiling by three-platform sequencing of whole genome, whole exome and transcriptome|
M Rusch, J Nakitandwe, S Shurtleff, S Newman, Z Zhang, MN Edmonson, ...
Nature communications 9 (1), 1-13, 2018
|Farewell to GBM-O: Genomic and transcriptomic profiling of glioblastoma with oligodendroglioma component reveals distinct molecular subgroups|
BH Hinrichs, S Newman, CL Appin, W Dunn, L Cooper, R Pauly, ...
Acta neuropathologica communications 4 (1), 4, 2016
|The relative timing of mutations in a breast cancer genome|
S Newman, KD Howarth, CD Greenman, GR Bignell, S Tavaré, ...
PloS one 8 (6), 2013
|Clinical genome sequencing uncovers potentially targetable truncations and fusions of MAP3K8 in spitzoid and other melanomas|
S Newman, L Fan, A Pribnow, A Silkov, SV Rice, S Lee, Y Shao, B Shaner, ...
Nature medicine 25 (4), 597-602, 2019