| Glutamatergic synaptic input to glioma cells drives brain tumour progression V Venkataramani, DI Tanev, C Strahle, A Studier-Fischer, L Fankhauser, ... Nature 573 (7775), 532-538, 2019 | 716 | 2019 |
| Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma S Tardito, A Oudin, SU Ahmed, F Fack, O Keunen, L Zheng, H Miletic, ... Nature cell biology 17 (12), 1556-1568, 2015 | 476 | 2015 |
| Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death G Ichim, J Lopez, SU Ahmed, N Muthalagu, E Giampazolias, ME Delgado, ... Molecular cell 57 (5), 860-872, 2015 | 394 | 2015 |
| ESTRO-ACROP guideline “target delineation of glioblastomas” M Niyazi, M Brada, AJ Chalmers, SE Combs, SC Erridge, A Fiorentino, ... Radiotherapy and oncology 118 (1), 35-42, 2016 | 387 | 2016 |
| Low-Dose Hyper-radiosensitivity: A Consequence of Ineffective Cell Cycle Arrest of Radiation-Damaged G2-Phase Cells B Marples, BG Wouters, SJ Collis, AJ Chalmers, MC Joiner Radiation research 161 (3), 247-255, 2004 | 285 | 2004 |
| Clinical development of new drug–radiotherapy combinations RA Sharma, R Plummer, JK Stock, TA Greenhalgh, O Ataman, S Kelly, ... Nature reviews Clinical oncology 13 (10), 627-642, 2016 | 280 | 2016 |
| Replication-dependent radiosensitization of human glioma cells by inhibition of poly (ADP-Ribose) polymerase: mechanisms and therapeutic potential FA Dungey, DA Löser, AJ Chalmers International Journal of Radiation Oncology* Biology* Physics 72 (4), 1188-1197, 2008 | 243 | 2008 |
| Psychosocial and supportive-care needs in high-grade glioma S Catt, A Chalmers, L Fallowfield The lancet oncology 9 (9), 884-891, 2008 | 240 | 2008 |
| Systematic review of supportive care needs in patients with primary malignant brain tumors E Ford, S Catt, A Chalmers, L Fallowfield Neuro-oncology 14 (4), 392-404, 2012 | 238 | 2012 |
| Stereotactic ablative radiotherapy for the comprehensive treatment of 4–10 oligometastatic tumors (SABR-COMET-10): study protocol for a randomized phase III trial DA Palma, R Olson, S Harrow, RJM Correa, F Schneiders, CJA Haasbeek, ... BMC cancer 19, 1-15, 2019 | 190 | 2019 |
| Selective inhibition of parallel DNA damage response pathways optimizes radiosensitization of glioblastoma stem-like cells SU Ahmed, R Carruthers, L Gilmour, S Yildirim, C Watts, AJ Chalmers Cancer research 75 (20), 4416-4428, 2015 | 186 | 2015 |
| PARP-1, PARP-2, and the cellular response to low doses of ionizing radiation A Chalmers, P Johnston, M Woodcock, M Joiner, B Marples International Journal of Radiation Oncology* Biology* Physics 58 (2), 410-419, 2004 | 170 | 2004 |
| A novel 3D human glioblastoma cell culture system for modeling drug and radiation responses N Gomez-Roman, K Stevenson, L Gilmour, G Hamilton, AJ Chalmers Neuro-oncology 19 (2), 229-241, 2017 | 157 | 2017 |
| Poly (ADP-ribose) polymerase inhibition as a model for synthetic lethality in developing radiation oncology targets AJ Chalmers, M Lakshman, N Chan, RG Bristow Seminars in radiation oncology 20 (4), 274-281, 2010 | 152 | 2010 |
| Sensitization to radiation and alkylating agents by inhibitors of poly (ADP-ribose) polymerase is enhanced in cells deficient in DNA double-strand break repair DA Löser, A Shibata, AK Shibata, LJ Woodbine, PA Jeggo, AJ Chalmers Molecular cancer therapeutics 9 (6), 1775-1787, 2010 | 150 | 2010 |
| Replication stress drives constitutive activation of the DNA damage response and radioresistance in glioblastoma stem-like cells RD Carruthers, SU Ahmed, S Ramachandran, K Strathdee, KM Kurian, ... Cancer research 78 (17), 5060-5071, 2018 | 146 | 2018 |
| Abrogation of radioresistance in glioblastoma stem-like cells by inhibition of ATM kinase R Carruthers, SU Ahmed, K Strathdee, N Gomez-Roman, ... Molecular oncology 9 (1), 192-203, 2015 | 142 | 2015 |
| The potential role and application of PARP inhibitors in cancer treatment AJ Chalmers British medical bulletin 89 (1), 23-40, 2009 | 139 | 2009 |
| Topoisomerase I inhibition in colorectal cancer: biomarkers and therapeutic targets DC Gilbert, AJ Chalmers, SF El-Khamisy British journal of cancer 106 (1), 18-24, 2012 | 136 | 2012 |
| Enhanced radiosensitization of human glioma cells by combining inhibition of poly (ADP-ribose) polymerase with inhibition of heat shock protein 90 FA Dungey, KW Caldecott, AJ Chalmers Molecular cancer therapeutics 8 (8), 2243-2254, 2009 | 131 | 2009 |
Lesley J. FallowfieldDirector SHORE-C, University of SussexVerified email at sussex.ac.uk
