Large-scale prediction and testing of drug activity on side-effect targets E Lounkine, MJ Keiser, S Whitebread, D Mikhailov, J Hamon, JL Jenkins, ... Nature 486 (7403), 361-367, 2012 | 937 | 2012 |
Mechanisms of inflammatory pain BL Kidd, LA Urban British journal of anaesthesia 87 (1), 3-11, 2001 | 909 | 2001 |
Epilepsy, hyperalgesia, impaired memory, and loss of pre-and postsynaptic GABAB responses in mice lacking GABAB (1) V Schuler, C Lüscher, C Blanchet, N Klix, G Sansig, K Klebs, M Schmutz, ... Neuron 31 (1), 47-58, 2001 | 653 | 2001 |
A rat model of bone cancer pain SJ Medhurst, K Walker, M Bowes, BL Kidd, M Glatt, M Muller, ... Pain 96 (1), 129-140, 2002 | 526 | 2002 |
The VR1 antagonist capsazepine reverses mechanical hyperalgesia in models of inflammatory and neuropathic pain KM Walker, L Urban, SJ Medhurst, S Patel, M Panesar, AJ Fox, P McIntyre Journal of pharmacology and experimental therapeutics 304 (1), 56-62, 2003 | 454 | 2003 |
The role of central and peripheral Cannabinoid1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain A Fox, A Kesingland, C Gentry, K McNair, S Patel, L Urban, I James Pain 92 (1), 91-100, 2001 | 451 | 2001 |
Keynote review: in vitro safety pharmacology profiling: an essential tool for successful drug development S Whitebread, J Hamon, D Bojanic, L Urban Drug discovery today 10 (21), 1421-1433, 2005 | 441 | 2005 |
TRPV4: molecular conductor of a diverse orchestra JPM White, M Cibelli, L Urban, B Nilius, JG McGeown, I Nagy Physiological reviews 96 (3), 911-973, 2016 | 398 | 2016 |
Analysis of pharmacology data and the prediction of adverse drug reactions and off‐target effects from chemical structure A Bender, J Scheiber, M Glick, JW Davies, K Azzaoui, J Hamon, L Urban, ... ChemMedChem: Chemistry Enabling Drug Discovery 2 (6), 861-873, 2007 | 393 | 2007 |
Intrathecally administered endotoxin or cytokines produce allodynia, hyperalgesia and changes in spinal cord neuronal responses to nociceptive stimuli in the rat AJ Reeve, S Patel, A Fox, K Walker, L Urban European Journal of Pain 4 (3), 247-257, 2000 | 380 | 2000 |
Cannabinoid 1 receptors are expressed in nociceptive primary sensory neurons J Ahluwalia, L Urban, M Capogna, S Bevan, I Nagy Neuroscience 100 (4), 685-688, 2000 | 371 | 2000 |
Modulation of spinal excitability: co-operation between neurokinin and excitatory amino acid neurotransmitters L Urban, SWN Thompson, A Dray Trends in neurosciences 17 (10), 432-438, 1994 | 354 | 1994 |
The role of the vanilloid (capsaicin) receptor (TRPV1) in physiology and pathology I Nagy, P Sántha, G Jancsó, L Urbán European journal of pharmacology 500 (1-3), 351-369, 2004 | 350 | 2004 |
Pharmacology of chronic pain A Dray, L Urban, A Dickenson Trends in pharmacological sciences 15 (6), 190-197, 1994 | 347 | 1994 |
Critical evaluation of the streptozotocin model of painful diabetic neuropathy in the rat A Fox, C Eastwood, C Gentry, D Manning, L Urban Pain 81 (3), 307-316, 1999 | 277 | 1999 |
Slow excitatory transmission in rat dorsal horn: possible mediation by peptides L Urban, M Randić Brain research 290 (2), 336-341, 1984 | 273 | 1984 |
mGlu5 receptors and nociceptive function II. mGlu5 receptors functionally expressed on peripheral sensory neurones mediate inflammatory hyperalgesia K Walker, A Reeve, M Bowes, J Winter, G Wotherspoon, A Davis, ... Neuropharmacology 40 (1), 10-19, 2001 | 263 | 2001 |
The effects of GABAB agonists and gabapentin on mechanical hyperalgesia in models of neuropathic and inflammatory pain in the rat S Patel, S Naeem, A Kesingland, W Froestl, M Capogna, L Urban, A Fox Pain 90 (3), 217-226, 2001 | 245 | 2001 |
An in vitro study of the properties of single vagal afferents innervating guinea‐pig airways. AJ Fox, PJ Barnes, L Urban, A Dray The Journal of Physiology 469 (1), 21-35, 1993 | 214 | 1993 |
Modeling promiscuity based on in vitro safety pharmacology profiling data K Azzaoui, J Hamon, B Faller, S Whitebread, E Jacoby, A Bender, ... ChemMedChem: Chemistry Enabling Drug Discovery 2 (6), 874-880, 2007 | 210 | 2007 |