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Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a “Kidney Disease: Improving Global Outcomes”(KDIGO) Controversies Conference THJ Goodship, HT Cook, F Fakhouri, FC Fervenza, V Frémeaux-Bacchi, ... Kidney international 91 (3), 539-551, 2017 | 723 | 2017 |
Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration JM Seddon, Y Yu, EC Miller, R Reynolds, PL Tan, S Gowrisankar, ... Nature genetics 45 (11), 1366-1370, 2013 | 501 | 2013 |
C-terminal truncations in human 3′-5′ DNA exonuclease TREX1 cause autosomal dominant retinal vasculopathy with cerebral leukodystrophy A Richards, AMJM Van Den Maagdenberg, JC Jen, D Kavanagh, ... Nature genetics 39 (9), 1068-1070, 2007 | 472 | 2007 |
Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical … I Moore, L Strain, I Pappworth, D Kavanagh, PN Barlow, AP Herbert, ... Blood, The Journal of the American Society of Hematology 115 (2), 379-387, 2010 | 413 | 2010 |
Thrombotic microangiopathy and the kidney V Brocklebank, KM Wood, D Kavanagh Clinical Journal of the American Society of Nephrology 13 (2), 300-317, 2018 | 394 | 2018 |
Atypical hemolytic uremic syndrome D Kavanagh, TH Goodship, A Richards Seminars in nephrology 33 (6), 508-530, 2013 | 383 | 2013 |
C3 glomerulopathy—understanding a rare complement-driven renal disease RJH Smith, GB Appel, AM Blom, HT Cook, VD D’Agati, F Fakhouri, ... Nature reviews nephrology 15 (3), 129-143, 2019 | 362 | 2019 |
Mutations in complement regulatory proteins predispose to preeclampsia: a genetic analysis of the PROMISSE cohort JE Salmon, C Heuser, M Triebwasser, MK Liszewski, D Kavanagh, ... PLoS medicine 8 (3), e1001013, 2011 | 337 | 2011 |
Atypical aHUS: state of the art CM Nester, T Barbour, SR de Cordoba, MA Dragon-Durey, ... Molecular immunology 67 (1), 31-42, 2015 | 334 | 2015 |
Mutations in complement factor I predispose to development of atypical hemolytic uremic syndrome D Kavanagh, EJ Kemp, E Mayland, RJ Winney, JS Duffield, G Warwick, ... Journal of the American Society of Nephrology 16 (7), 2150-2155, 2005 | 304 | 2005 |
Structural basis for sialic acid–mediated self-recognition by complement factor H BS Blaum, JP Hannan, AP Herbert, D Kavanagh, D Uhrín, T Stehle Nature chemical biology 11 (1), 77-82, 2015 | 295 | 2015 |
Structural basis for engagement by complement factor H of C3b on a self surface HP Morgan, CQ Schmidt, M Guariento, BS Blaum, D Gillespie, AP Herbert, ... Nature structural & molecular biology 18 (4), 463-470, 2011 | 287 | 2011 |
Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome EA Moulton, D Kavanagh, J Blouin, A Caudy, N Arzouk, R Cleper, ... Journal of the American Society of Nephrology 17 (7), 2017-2025, 2006 | 278 | 2006 |
Extended haplotypes in the complement factor H (CFH) and CFH‐related (CFHR) family of genes protect against age‐related macular degeneration … GS Hageman, LS Hancox, AJ Taiber, KM Gehrs, DH Anderson, ... Annals of medicine 38 (8), 592-604, 2006 | 276 | 2006 |
A new map of glycosaminoglycan and C3b binding sites on factor H CQ Schmidt, AP Herbert, D Kavanagh, C Gandy, CJ Fenton, BS Blaum, ... The Journal of Immunology 181 (4), 2610-2619, 2008 | 271 | 2008 |
Peritoneal dialysis-associated peritonitis in Scotland (1999–2002) D Kavanagh, GJ Prescott, RA Mactier Nephrology Dialysis Transplantation 19 (10), 2584-2591, 2004 | 244 | 2004 |
Hemolytic uremic syndrome in pregnancy and postpartum A Bruel, D Kavanagh, M Noris, Y Delmas, EKS Wong, E Bresin, F Provôt, ... Clinical Journal of the American Society of Nephrology 12 (8), 1237-1247, 2017 | 230 | 2017 |
Genetics and complement in atypical HUS D Kavanagh, T Goodship Pediatric nephrology 25, 2431-2442, 2010 | 209 | 2010 |
The binding of factor H to a complex of physiological polyanions and C3b on cells is impaired in atypical hemolytic uremic syndrome VP Ferreira, AP Herbert, C Cortés, KA McKee, BS Blaum, ST Esswein, ... The Journal of Immunology 182 (11), 7009-7018, 2009 | 206 | 2009 |