BRAF status and mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 activity indicate sensitivity of melanoma cells to anthrax lethal toxin RJ Abi-Habib, JO Urieto, S Liu, SH Leppla, NS Duesbery, AE Frankel Molecular Cancer Therapeutics 4 (9), 1303-1310, 2005 | 95 | 2005 |
Hippocampal programmed cell death after status epilepticus: evidence for NMDA‐receptor and ceramide‐mediated mechanisms MA Mikati, RJ Abi‐Habib, ME El Sabban, GS Dbaibo, RM Kurdi, ... Epilepsia 44 (3), 282-291, 2003 | 85 | 2003 |
Arginine deprivation: A potential therapeutic for cancer cell metastasis? A review H Al-Koussa, N El Mais, H Maalouf, R Abi-Habib, M El-Sibai Cancer Cell International 20, 1-7, 2020 | 76 | 2020 |
Phase 1 and 2 studies demonstrate the safety and efficacy of intraprostatic injection of PRX302 for the targeted treatment of lower urinary tract symptoms secondary to benign … SR Denmeade, B Egerdie, G Steinhoff, R Merchant, R Abi-Habib, ... European urology 59 (5), 747-754, 2011 | 72 | 2011 |
A urokinase-activated recombinant anthrax toxin is selectively cytotoxic to many human tumor cell types RJ Abi-Habib, R Singh, S Liu, TH Bugge, SH Leppla, AE Frankel Molecular cancer therapeutics 5 (10), 2556-2562, 2006 | 71 | 2006 |
Human recombinant arginase I (Co)-PEG5000 [HuArgI (Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human glioblastoma cells O Khoury, N Ghazale, E Stone, M El-Sibai, AE Frankel, RJ Abi-Habib Journal of neuro-oncology 122, 75-85, 2015 | 70 | 2015 |
A urokinase-activated recombinant diphtheria toxin targeting the granulocyte-macrophage colony-stimulating factor receptor is selectively cytotoxic to human acute myeloid … RJ Abi-Habib, S Liu, TH Bugge, SH Leppla, AE Frankel Blood 104 (7), 2143-2148, 2004 | 62 | 2004 |
Human recombinant arginase I (Co)-PEG5000 [HuArgI (Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells R Tanios, A Bekdash, E Kassab, E Stone, G Georgiou, AE Frankel, ... Leukemia Research 37 (11), 1565-1571, 2013 | 57 | 2013 |
Systemic anthrax lethal toxin therapy produces regressions of subcutaneous human melanoma tumors in athymic nude mice RJ Abi-Habib, R Singh, SH Leppla, JJ Greene, Y Ding, B Berghuis, ... Clinical cancer research 12 (24), 7437-7443, 2006 | 57 | 2006 |
Phototoxicity of strained Ru (ii) complexes: is it the metal complex or the dissociating ligand? DF Azar, H Audi, S Farhat, M El-Sibai, RJ Abi-Habib, RS Khnayzer Dalton Transactions 46 (35), 11529-11532, 2017 | 53 | 2017 |
Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells M Tawil, A Bekdash, M Mroueh, CF Daher, RJ Abi-Habib Asian Pacific Journal of Cancer Prevention 16 (2), 761-767, 2015 | 49 | 2015 |
Cytotoxicity of [HuArgI (co)-PEG5000]-induced arginine deprivation to ovarian Cancer cells is autophagy dependent G Nasreddine, M El-Sibai, RJ Abi-Habib Investigational new drugs 38 (1), 10-19, 2020 | 38 | 2020 |
Changes in sphingomyelinases, ceramide, Bax, Bcl2, and caspase-3 during and after experimental status epilepticus MA Mikati, M Zeinieh, R Abi Habib, J El Hokayem, A Rahmeh, ... Epilepsy research 81 (2-3), 161-166, 2008 | 38 | 2008 |
3D modeling in cancer studies OE Atat, Z Farzaneh, M Pourhamzeh, F Taki, R Abi-Habib, M Vosough, ... Human Cell, 1-14, 2022 | 35 | 2022 |
Human recombinant arginase I [HuArgI (Co)-PEG5000]-induced arginine depletion inhibits colorectal cancer cell migration and invasion H Al-Koussa, M Al-Haddad, R Abi-Habib, M El-Sibai International journal of molecular sciences 20 (23), 6018, 2019 | 30 | 2019 |
Cytotoxicity of anthrax lethal toxin to human acute myeloid leukemia cells is nonapoptotic and dependent on extracellular signal-regulated kinase 1/2 activity E Kassab, M Darwish, Z Timsah, SH Liu, SH Leppla, AE Frankel, ... Translational oncology 6 (1), 25-32, 2013 | 28 | 2013 |
Targeting the MAP kinase pathway in astrocytoma cells using a recombinant anthrax lethal toxin as a way to inhibit cell motility and invasion S Al-Dimassi, G Salloum, B Saykali, O Khoury, S Liu, SH Leppla, ... International journal of oncology 48 (5), 1913-1920, 2016 | 27 | 2016 |
Doxironide magnetic nanoparticles for selective drug delivery to human acute myeloid leukemia K El-Boubbou, D Azar, A Bekdash, RJ Abi-Habib Journal of Biomedical Nanotechnology 13 (5), 500-512, 2017 | 20 | 2017 |
Diphtheria toxin-murine granulocyte-macrophage colony-stimulating factor–induced hepatotoxicity is mediated by Kupffer cells MM Westcott, RJ Abi-Habib, KA Cohen, MC Willingham, S Liu, TH Bugge, ... Molecular Cancer Therapeutics 3 (12), 1681-1689, 2004 | 20 | 2004 |
[HuArgI (co)-PEG5000]-induced arginine deprivation leads to autophagy dependent cell death in pancreatic cancer cells N Khalil, RJ Abi-Habib Investigational New Drugs 38 (5), 1236-1246, 2020 | 19 | 2020 |