Jonathan H Tobias
Jonathan H Tobias
Professor of Rheumatology, University of Bristol
Verified email at
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Common variants near MC4R are associated with fat mass, weight and risk of obesity
RJF Loos, CM Lindgren, S Li, E Wheeler, JH Zhao, I Prokopenko, ...
Nature genetics 40 (6), 768-775, 2008
Using multiple genetic variants as instrumental variables for modifiable risk factors
TM Palmer, DA Lawlor, RM Harbord, NA Sheehan, JH Tobias, ...
Statistical methods in medical research 21 (3), 223-242, 2012
An atlas of genetic influences on osteoporosis in humans and mice
JA Morris, JP Kemp, SE Youlten, L Laurent, JG Logan, RC Chai, ...
Nature genetics 51 (2), 258-266, 2019
Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture
HF Zheng, V Forgetta, YH Hsu, K Estrada, A Rosello‐Diez, PJ Leo, ...
Nature 526 (7571), 112-117, 2015
A common variant of HMGA2 is associated with adult and childhood height in the general population
MN Weedon, G Lettre, RM Freathy, CM Lindgren, BF Voight, JRB Perry, ...
Nature genetics 39 (10), 1245-1250, 2007
Association between bone mass and fractures in children: a prospective cohort study
EM Clark, AR Ness, NJ Bishop, JH Tobias
Journal of bone and mineral research 21 (9), 1489-1495, 2006
Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis
JP Kemp, JA Morris, C Medina-Gomez, V Forgetta, NM Warrington, ...
Nature genetics 49 (10), 1468-1475, 2017
Estrogen maintains trabecular bone volume in rats not only by suppression of bone resorption but also by stimulation of bone formation.
J Chow, JH Tobias, KW Colston, TJ Chambers
The Journal of clinical investigation 89 (1), 74-78, 1992
WNT16 Influences Bone Mineral Density, Cortical Bone Thickness, Bone Strength, and Osteoporotic Fracture Risk
HF Zheng, JH Tobias, E Duncan, DM Evans, J Eriksson, L Paternoster, ...
PLoS genetics 8 (7), e1002745, 2012
Association between bone density and fractures in children: a systematic review and meta-analysis
EM Clark, JH Tobias, AR Ness
Pediatrics 117 (2), e291-e297, 2006
Life-course genome-wide association study meta-analysis of total body BMD and assessment of age-specific effects
C Medina-Gomez, JP Kemp, K Trajanoska, J Luan, A Chesi, TS Ahluwalia, ...
The American Journal of Human Genetics 102 (1), 88-102, 2018
90-day mortality after 409 096 total hip replacements for osteoarthritis, from the National Joint Registry for England and Wales: a retrospective analysis
LP Hunt, Y Ben-Shlomo, EM Clark, P Dieppe, A Judge, AJ MacGregor, ...
The Lancet 382 (9898), 1097-1104, 2013
Intervertebral disc degeneration can lead to “stress-shielding” of the anterior vertebral body: a cause of osteoporotic vertebral fracture?
P Pollintine, P Dolan, JH Tobias, MA Adams
Spine 29 (7), 774-782, 2004
Adipose tissue stimulates bone growth in prepubertal children
EM Clark, AR Ness, JH Tobias, ...
The Journal of Clinical Endocrinology & Metabolism 91 (7), 2534-2541, 2006
Intervertebral disc degeneration can predispose to anterior vertebral fractures in the thoracolumbar spine
MA Adams, P Pollintine, JH Tobias, GK Wakley, P Dolan
Journal of Bone and Mineral Research 21 (9), 1409-1416, 2006
Association of maternal vitamin D status during pregnancy with bone-mineral content in offspring: a prospective cohort study
DA Lawlor, AK Wills, A Fraser, A Sayers, WD Fraser, JH Tobias
The Lancet 381 (9884), 2176-2183, 2013
Epidemiology of generalized joint laxity (hypermobility) in fourteen‐year‐old children from the UK: A population‐based evaluation
J Clinch, K Deere, A Sayers, S Palmer, C Riddoch, JH Tobias, EM Clark
Arthritis & Rheumatism 63 (9), 2819-2827, 2011
Habitual levels of physical activity influence bone mass in 11‐year‐old children from the United Kingdom: findings from a large population‐based cohort
JH Tobias, CD Steer, CG Mattocks, C Riddoch, AR Ness
Journal of Bone and Mineral Research 22 (1), 101-109, 2007
Meta-Analysis of Genome-Wide Scans for Total Body BMD in Children and Adults Reveals Allelic Heterogeneity and Age-Specific Effects at the WNT16 Locus
C Medina-Gomez, JP Kemp, K Estrada, J Eriksson, J Liu, S Reppe, ...
PLoS genetics 8 (7), e1002718, 2012
45-day mortality after 467 779 knee replacements for osteoarthritis from the National Joint Registry for England and Wales: an observational study
LP Hunt, Y Ben-Shlomo, EM Clark, P Dieppe, A Judge, AJ MacGregor, ...
The Lancet 384 (9952), 1429-1436, 2014
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