|Replicon clusters are stable units of chromosome structure: evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells|
DA Jackson, A Pombo
The Journal of cell biology 140 (6), 1285-1295, 1998
|Intermingling of chromosome territories in interphase suggests role in translocations and transcription-dependent associations|
MR Branco, A Pombo
PLoS biology 4 (5), e138, 2006
|Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells|
JK Stock, S Giadrossi, M Casanova, E Brookes, M Vidal, H Koseki, ...
Nature cell biology 9 (12), 1428, 2007
|Dendritic cells interact directly with naive B lymphocytes to transfer antigen and initiate class switching in a primary T-dependent response|
M Wykes, A Pombo, C Jenkins, GG MacPherson
The Journal of Immunology 161 (3), 1313-1319, 1998
|Active RNA polymerases are localized within discrete transcription “factories' in human nuclei|
FJ Iborra, A Pombo, DA Jackson, PR Cook
Journal of cell science 109 (6), 1427-1436, 1996
|Short RNAs are transcribed from repressed polycomb target genes and interact with polycomb repressive complex-2|
A Kanhere, K Viiri, CC Araújo, J Rasaiyaah, RD Bouwman, WA Whyte, ...
Molecular cell 38 (5), 675-688, 2010
|Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells|
E Arner, CO Daub, K Vitting-Seerup, R Andersson, B Lilje, F Drabløs, ...
Science 347 (6225), 1010-1014, 2015
|Complexity of chromatin folding is captured by the strings and binders switch model|
M Barbieri, M Chotalia, J Fraser, LM Lavitas, J Dostie, A Pombo, ...
Proceedings of the National Academy of Sciences 109 (40), 16173-16178, 2012
|Three-dimensional genome architecture: players and mechanisms|
A Pombo, N Dillon
Nature reviews Molecular cell biology 16 (4), 245, 2015
|Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators|
D Landeira, S Sauer, R Poot, M Dvorkina, L Mazzarella, HF Jørgensen, ...
Nature cell biology 12 (6), 618, 2010
|Regional specialization in human nuclei: visualization of discrete sites of transcription by RNA polymerase III|
A Pombo, DA Jackson, M Hollinshead, Z Wang, RG Roeder, PR Cook
The EMBO journal 18 (8), 2241-2253, 1999
|Localization of a putative transcriptional regulator (ATRX) at pericentromeric heterochromatin and the short arms of acrocentric chromosomes|
TL McDowell, RJ Gibbons, H Sutherland, DM O’Rourke, WA Bickmore, ...
Proceedings of the National Academy of Sciences 96 (24), 13983-13988, 1999
|Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs|
E Brookes, I de Santiago, D Hebenstreit, KJ Morris, T Carroll, SQ Xie, ...
Cell stem cell 10 (2), 157-170, 2012
|Formation of new chromatin domains determines pathogenicity of genomic duplications|
M Franke, DM Ibrahim, G Andrey, W Schwarzer, V Heinrich, R Schöpflin, ...
Nature 538 (7624), 265, 2016
|Variant histone H3. 3 marks promoters of transcriptionally active genes during mammalian cell division|
CM Chow, A Georgiou, H Szutorisz, AM e Silva, A Pombo, I Barahona, ...
EMBO reports 6 (4), 354-360, 2005
|Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation|
J Fraser, C Ferrai, AM Chiariello, M Schueler, T Rito, G Laudanno, ...
Molecular systems biology 11 (12), 2015
|Complex multi-enhancer contacts captured by genome architecture mapping|
RA Beagrie, A Scialdone, M Schueler, DCA Kraemer, M Chotalia, SQ Xie, ...
Nature 543 (7646), 519, 2017
|The balance sheet for transcription: an analysis of nuclear RNA metabolism in mammalian cells|
DA Jackson, ANA Pombo, F IBORRA
The FASEB Journal 14 (2), 242-254, 2000
|Adenovirus replication and transcription sites are spatially separated in the nucleus of infected cells.|
A Pombo, J Ferreira, E Bridge, M Carmo‐Fonseca
The EMBO journal 13 (21), 5075-5085, 1994
|Modifications of RNA polymerase II are pivotal in regulating gene expression states|
E Brookes, A Pombo
EMBO reports 10 (11), 1213-1219, 2009