Benjamin Werner
TitleCited byYear
Identification of neutral tumor evolution across cancer types
MJ Williams, B Werner, CP Barnes, TA Graham, A Sottoriva
Nature genetics 48 (3), 238, 2016
2572016
Dynamics of mutant cells in hierarchical organized tissues
B Werner, D Dingli, T Lenaerts, JM Pacheco, A Traulsen
PLoS computational biology 7 (12), e1002290, 2011
522011
Quantification of subclonal selection in cancer from bulk sequencing data
MJ Williams, B Werner, T Heide, C Curtis, CP Barnes, A Sottoriva, ...
Nature genetics 50 (6), 895, 2018
412018
A deterministic model for the occurrence and dynamics of multiple mutations in hierarchically organized tissues
B Werner, D Dingli, A Traulsen
Journal of The Royal Society Interface 10 (85), 20130349, 2013
372013
The cancer stem cell fraction in hierarchically organized tumors can be estimated using mathematical modeling and patient-specific treatment trajectories
B Werner, JG Scott, A Sottoriva, ARA Anderson, A Traulsen, PM Altrock
Cancer research 76 (7), 1705-1713, 2016
342016
Reconstructing the in vivo dynamics of hematopoietic stem cells from telomere length distributions
B Werner, F Beier, S Hummel, S Balabanov, L Lassay, T Orlikowsky, ...
eLife, e08687v2, 2015
342015
Longitudinal liquid biopsy and mathematical modeling of clonal evolution forecast time to treatment failure in the PROSPECT-C phase II colorectal cancer clinical trial
KH Khan, D Cunningham, B Werner, G Vlachogiannis, I Spiteri, T Heide, ...
Cancer discovery 8 (10), 1270-1285, 2018
322018
Dynamics of leukemia stem-like cell extinction in acute promyelocytic leukemia
B Werner, RE Gallagher, EM Paietta, MR Litzow, MS Tallman, PH Wiernik, ...
Cancer research 74 (19), 5386-5396, 2014
172014
Should tissue structure suppress or amplify selection to minimize cancer risk?
L Hindersin, B Werner, D Dingli, A Traulsen
Biology direct 11 (1), 41, 2016
152016
Self-tolerance in a minimal model of the idiotypic network
R Schulz, BD Werner, U Behn
Frontiers in immunology 5, 86, 2014
132014
Dynamics of resistance development to imatinib under increasing selection pressure: a combination of mathematical models and in vitro data
B Werner, D Lutz, TH Brümmendorf, A Traulsen, S Balabanov
PLoS One 6 (12), e28955, 2011
132011
Dynamical trade-offs arise from antagonistic coevolution and decrease intraspecific diversity
W Huang, A Traulsen, B Werner, T Hiltunen, L Becks
Nature communications 8 (1), 2059, 2017
122017
The impact of random frequency-dependent mutations on the average population fitness
W Huang, B Werner, A Traulsen
BMC Evolutionary Biology 12 (1), 160, 2012
112012
Carbon dating cancer: defining the chronology of metastatic progression in colorectal cancer
H Lote, I Spiteri, L Ermini, A Vatsiou, A Roy, A McDonald, N Maka, ...
Annals of Oncology 28 (6), 1243-1249, 2017
102017
Detecting truly clonal alterations from multi-region profiling of tumours
B Werner, A Traulsen, A Sottoriva, D Dingli
Scientific reports 7, 44991, 2017
92017
Reply to ‘Neutral tumor evolution?’
T Heide, L Zapata, MJ Williams, B Werner, G Caravagna, CP Barnes, ...
Nature genetics 50 (12), 1633, 2018
72018
Variation of mutational burden in healthy human tissues suggests non-random strand segregation and allows measuring somatic mutation rates
B Werner, A Sottoriva
PLoS computational biology 14 (6), e1006233, 2018
72018
Replicative cellular age distributions in compartmentalized tissues
MA Böttcher, D Dingli, B Werner, A Traulsen
Journal of The Royal Society Interface 15 (145), 20180272, 2018
62018
Ontogenic growth as the root of fundamental differences between childhood and adult cancer
B Werner, A Traulsen, D Dingli
Stem Cells 34 (3), 543-550, 2016
62016
Evolutionary dynamics of residual disease in human glioblastoma
I Spiteri, G Caravagna, GD Cresswell, A Vatsiou, D Nichol, A Acar, ...
Annals of Oncology 30 (3), 456-463, 2018
52018
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Articles 1–20