| Discovery of second generation reversible covalent DPP1 inhibitors leading to an oxazepane amidoacetonitrile based clinical candidate (AZD7986) K Doyle, H Lönn, H Käck, A Van de Poël, S Swallow, P Gardiner, ... Journal of Medicinal Chemistry 59 (20), 9457-9472, 2016 | 62 | 2016 |
| Brain monoamine output alterations after a single venlafaxine challenge in experimental hepatic encephalopathy C Wikell, PBF Bergqvist, S Hjorth, G Apelqvist, H Björk, F Bengtsson Clinical neuropharmacology 21 (5), 296-306, 1998 | 30 | 1998 |
| Sustained administration of the antidepressant venlafaxine in rats: pharmacokinetic and pharmacodynamic findings. C Wikell, S Hjorth, G Apelqvist, J Kullingsjö, J Lundmark, PBF Bergqvist, ... Naunyn-Schmiedeberg's Archives of Pharmacology 363 (4), 2001 | 26 | 2001 |
| Pharmacokinetic and pharmacodynamic responses to chronic administration of the selective serotonin reuptake inhibitor citalopram in rats C Wikell, G Apelqvist, B Carlsson, S Hjorth, PBF Bergqvist, FC Kugelberg, ... Clinical neuropharmacology 22 (6), 327-336, 1999 | 24 | 1999 |
| Neutrophil maturation rate determines the effects of dipeptidyl peptidase 1 inhibition on neutrophil serine protease activity P Gardiner, C Wikell, S Clifton, J Shearer, A Benjamin, SA Peters British Journal of Pharmacology 173 (15), 2390-2401, 2016 | 23 | 2016 |
| Altered open-field behavior in experimental chronic hepatic encephalopathy after single venlafaxine and citalopram challenges G Apelqvist, C Wikell, B Hindfelt, PBF Bergqvist, G Andersson, ... Psychopharmacology 143, 408-416, 1999 | 23 | 1999 |
| Quantitative studies of testicular atrophy following portacaval shunt in rats AM Zaitoun, G Apelqvist, C Wikell, H Al‐mardini, F Bengtsson, CO Record Hepatology 28 (6), 1461-1466, 1998 | 21 | 1998 |
| Effect of citalopram on brain serotonin release in experimental hepatic encephalopathy: implications for thymoleptic drug safety in liver insufficiency PBF Bergqvist, C Wikell, S Hjorth, G Apelqvist, F Bengtsson Clinical neuropharmacology 20 (6), 511-522, 1997 | 15 | 1997 |
| Effects on drug disposition, brain monoamines and behavior after chronic treatment with the antidepressant venlafaxine in rats with experimental hepatic encephalopathy C Wikell, G Apelqvist, S Hjorth, J Kullingsjö, PBF Bergqvist, F Bengtsson European neuropsychopharmacology 12 (4), 327-336, 2002 | 14 | 2002 |
| Open‐Field Behavioural Alterations in Liver‐Impaired and Sham‐Operated Rats after Acute Exposure to the Antidepressant Venlafaxine FC Kugelberg, G Apelqvist, C Wikell, F Bengtsson Basic & clinical pharmacology & toxicology 97 (3), 155-161, 2005 | 11 | 2005 |
| Dynamic and kinetic effects of chronic citalopram treatment in experimental hepatic encephalopathy G Apelqvist, C Wikell, B Carlsson, S Hjorth, PBF Bergqvist, J Ahlner, ... Clinical neuropharmacology 23 (6), 304-317, 2000 | 10 | 2000 |
| p-chloroamphetamine-and d-fenfluramine-induced brain serotonin release in experimental portal-systemic encephalopathy PBF Bergqvist, S Hjorth, C Wikell, G Apelqvist, F Bengtsson Metabolic brain disease 12, 229-236, 1997 | 9 | 1997 |
| Disposition of venlafaxine enantiomers in rats with hepatic encephalopathy after chronic drug treatment C Wikell, CB Eap, M Josefsson, G Apelqvist, J Ahlner, P Baumann, ... Chirality 14 (4), 347-350, 2002 | 5 | 2002 |
| Effect of halving the dose of venlafaxine to adjust for putative pharmacokinetic and pharmacodynamic changes in an animal model of chronic hepatic encephalopathy C Wikell, FC Kugelberg, S Hjorth, G Apelqvist, F Bengtsson Clinical neuropharmacology 24 (6), 324-333, 2001 | 4 | 2001 |
| Inhibition of neutrophil serine protease activation with the reversible DPP1 inhibitor AZD7986 J Root, J Bernstrom, S Clifton, G Dahl, K Doyle, P Gardiner, ... C70. THE NEXT NEW THERAPEUTIC TARGET? TRANSLATIONAL STUDIES OF COPD …, 2016 | 1 | 2016 |
| C70 THE NEXT NEW THERAPEUTIC TARGET? TRANSLATIONAL STUDIES OF COPD THERAPIES: Inhibition Of Neutrophil Serine Protease Activation With The Reversible Dpp1 Inhibitor Azd7986 J Root, J Bernstrom, S Clifton, G Dahl, K Doyle, P Gardiner, ... American Journal of Respiratory and Critical Care Medicine 193, 1, 2016 | | 2016 |
| CATHEPSIN C INHIBITION: USING AN INDIRECT RESPONSE MODEL TO LINK NEUTROPHIL MATURATION RATE AND NEUTROPHIL SERINE PROTEASE ACTIVITY IN RAT P Gardiner, S Peters, C Wikell DRUG METABOLISM REVIEWS 47, 227-228, 2015 | | 2015 |
| Viral mimetic Poly (I: C) exacerbates cigarette smoke-induced pulmonary inflammation by facilitating the release of neutrophil-derived elastase A Borde, T Ottosson, C Wikell, A Vidal European Respiratory Journal 44 (Suppl 58), 2014 | | 2014 |
| Effects of a highly selective CXCR3 antagonist in two murine models of lung inflammation A Vidal, C Wikell, I Dainty European Respiratory Journal 44 (Suppl 58), 2014 | | 2014 |
| Antidepressant drug effects in vivo: Focus on pharmacokinetic and pharmacodynamic responses in different experimental paradigms C Wikell Lund University, 2001 | | 2001 |
