| Sequencing depth and coverage: key considerations in genomic analyses D Sims, I Sudbery, NE Ilott, A Heger, CP Ponting Nature Reviews Genetics 15 (2), 121-132, 2014 | 1797 | 2014 |
| KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands AM Farcas, NP Blackledge, I Sudbery, HK Long, JF McGouran, NR Rose, ... elife 1, e00205, 2012 | 513 | 2012 |
| Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly H Li, J Janssens, M De Waegeneer, SS Kolluru, K Davie, V Gardeux, ... Science 375 (6584), eabk2432, 2022 | 475 | 2022 |
| Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity I Bajrami, JR Frankum, A Konde, RE Miller, FL Rehman, R Brough, ... Cancer research 74 (1), 287-297, 2014 | 386 | 2014 |
| Long non-coding RNAs and enhancer RNAs regulate the lipopolysaccharide-induced inflammatory response in human monocytes NE Ilott, JA Heward, B Roux, E Tsitsiou, PS Fenwick, L Lenzi, I Goodhead, ... Nature communications 5 (1), 3979, 2014 | 340* | 2014 |
| Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates HK Long, D Sims, A Heger, NP Blackledge, C Kutter, ML Wright, ... elife 2, e00348, 2013 | 229 | 2013 |
| A blood atlas of COVID-19 defines hallmarks of disease severity and specificity DJ Ahern, Z Ai, M Ainsworth, C Allan, A Allcock, B Angus, MA Ansari, ... Cell 185 (5), 916-938. e58, 2022 | 202 | 2022 |
| High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencing D Sims, AM Mendes-Pereira, J Frankum, D Burgess, MA Cerone, ... Genome biology 12, 1-13, 2011 | 179 | 2011 |
| Functional viability profiles of breast cancer R Brough, JR Frankum, D Sims, A Mackay, AM Mendes-Pereira, I Bajrami, ... Cancer discovery 1 (3), 260-273, 2011 | 173 | 2011 |
| De novo point mutations in patients diagnosed with ataxic cerebral palsy R Parolin Schnekenberg, EM Perkins, JW Miller, WIL Davies, ... Brain 138 (7), 1817-1832, 2015 | 171 | 2015 |
| Next-generation sequencing of advanced prostate cancer treated with androgen-deprivation therapy P Rajan, IM Sudbery, MEM Villasevil, E Mui, J Fleming, M Davis, I Ahmad, ... European urology 66 (1), 32-39, 2014 | 164 | 2014 |
| Genome-wide functional screen identifies a compendium of genes affecting sensitivity to tamoxifen AM Mendes-Pereira, D Sims, T Dexter, K Fenwick, I Assiotis, I Kozarewa, ... Proceedings of the National Academy of Sciences 109 (8), 2730-2735, 2012 | 152 | 2012 |
| Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability MD Morgan, E Pairo-Castineira, K Rawlik, O Canela-Xandri, J Rees, ... Nature communications 9 (1), 5271, 2018 | 136 | 2018 |
| An essential role for the Zn2+ transporter ZIP7 in B cell development C Anzilotti, DJ Swan, B Boisson, M Deobagkar-Lele, C Oliveira, ... Nature immunology 20 (3), 350-361, 2019 | 125 | 2019 |
| SPG7 mutations are a common cause of undiagnosed ataxia G Pfeffer, A Pyle, H Griffin, J Miller, V Wilson, L Turnbull, K Fawcett, ... Neurology 84 (11), 1174-1176, 2015 | 125 | 2015 |
| Tuning the transcriptional response to hypoxia by inhibiting hypoxia-inducible factor (HIF) prolyl and asparaginyl hydroxylases MC Chan, NE Ilott, J Schödel, D Sims, A Tumber, K Lippl, DR Mole, ... Journal of Biological Chemistry 291 (39), 20661-20673, 2016 | 118 | 2016 |
| Parallel high-throughput RNA interference screens identify PINK1 as a potential therapeutic target for the treatment of DNA mismatch repair–deficient cancers SA Martin, M Hewish, D Sims, CJ Lord, A Ashworth Cancer research 71 (5), 1836-1848, 2011 | 116 | 2011 |
| An In Vivo Functional Screen Identifies ST6GalNAc2 Sialyltransferase as a Breast Cancer Metastasis Suppressor N Murugaesu, M Iravani, A Van Weverwijk, A Ivetic, DA Johnson, ... Cancer discovery 4 (3), 304-317, 2014 | 105 | 2014 |
| Co-transcriptional loading of RNA export factors shapes the human transcriptome N Viphakone, I Sudbery, L Griffith, CG Heath, D Sims, SA Wilson Molecular Cell 75 (2), 310-323. e8, 2019 | 103 | 2019 |
| De novo mutations in GRIN1 cause extensive bilateral polymicrogyria AE Fry, KA Fawcett, N Zelnik, H Yuan, BAN Thompson, L Shemer-Meiri, ... Brain 141 (3), 698-712, 2018 | 100 | 2018 |
Andreas HegerCGAT / WIMM / University of OxfordVerified email at imm.ox.ac.uk
