Wnt addiction of genetically defined cancers reversed by PORCN inhibition B Madan, Z Ke, N Harmston, SY Ho, AO Frois, J Alam, DA Jeyaraj, ... Oncogene 35 (17), 2197-2207, 2016 | 362 | 2016 |
Topologically associating domains are ancient features that coincide with Metazoan clusters of extreme noncoding conservation N Harmston, E Ing-Simmons, G Tan, M Perry, M Merkenschlager, ... Nature communications 8 (1), 441, 2017 | 195 | 2017 |
Chromatin and epigenetic features of long-range gene regulation N Harmston, B Lenhard Nucleic acids research 41 (15), 7185-7199, 2013 | 127 | 2013 |
Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease C Ferrari Bardile, M Garcia-Miralles, NS Caron, NA Rayan, SR Langley, ... Proceedings of the National Academy of Sciences 116 (19), 9622-9627, 2019 | 102 | 2019 |
The mystery of extreme non-coding conservation N Harmston, A Barešić, B Lenhard Philosophical Transactions of the Royal Society B: Biological Sciences 368 …, 2013 | 91 | 2013 |
Changes in macrophage transcriptome associate with systemic sclerosis and mediate GSDMA contribution to disease risk A Moreno-Moral, M Bagnati, S Koturan, JH Ko, C Fonseca, N Harmston, ... Annals of the rheumatic diseases 77 (4), 596-601, 2018 | 88 | 2018 |
A high-resolution map of human RNA translation SP Chothani, E Adami, AA Widjaja, SR Langley, S Viswanathan, CJ Pua, ... Molecular cell 82 (15), 2885-2899. e8, 2022 | 85 | 2022 |
Wnt proteins synergize to activate β-catenin signaling A Alok, Z Lei, NS Jagannathan, S Kaur, N Harmston, SG Rozen, ... Journal of cell science 130 (9), 1532-1544, 2017 | 84 | 2017 |
Unbiased profiling of isogenic Huntington disease hPSC-derived CNS and peripheral cells reveals strong cell-type specificity of CAG length effects J Ooi, SR Langley, X Xu, KH Utami, B Sim, Y Huang, NP Harmston, ... Cell Reports 26 (9), 2494-2508. e7, 2019 | 83 | 2019 |
WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling H Chen, A Moreno-Moral, F Pesce, N Devapragash, M Mancini, EL Heng, ... Nature communications 10 (1), 3616, 2019 | 71* | 2019 |
Temporal dynamics of Wnt-dependent transcriptome reveal an oncogenic Wnt/MYC/ribosome axis B Madan, N Harmston, G Nallan, A Montoya, P Faull, E Petretto, ... The Journal of clinical investigation 128 (12), 5620-5633, 2019 | 66 | 2019 |
GenomicInteractions: An R/Bioconductor package for manipulating and investigating chromatin interaction data N Harmston, E Ing-Simmons, M Perry, A Barešić, B Lenhard BMC genomics 16, 1-9, 2015 | 64 | 2015 |
What the papers say: Text mining for genomics and systems biology N Harmston, W Filsell, MPH Stumpf Human genomics 5, 1-13, 2010 | 64 | 2010 |
In vivo generation of post-infarct human cardiac muscle by laminin-promoted cardiovascular progenitors L Yap, JW Wang, A Moreno-Moral, LY Chong, Y Sun, N Harmston, ... Cell reports 26 (12), 3231-3245. e9, 2019 | 54 | 2019 |
The functional landscape of patient-derived RNF43 mutations predicts sensitivity to Wnt inhibition J Yu, PAM Yusoff, DTJ Woutersen, P Goh, N Harmston, R Smits, ... Cancer research 80 (24), 5619-5632, 2020 | 46 | 2020 |
WNT inhibition creates a BRCA‐like state in Wnt‐addicted cancer A Kaur, JYS Lim, S Sepramaniam, S Patnaik, N Harmston, MA Lee, ... EMBO molecular medicine 13 (4), e13349, 2021 | 39 | 2021 |
Biologically relevant laminin as chemically defined and fully human platform for human epidermal keratinocyte culture MS Tjin, AWC Chua, A Moreno-Moral, LY Chong, PY Tang, NP Harmston, ... Nature communications 9 (1), 4432, 2018 | 36 | 2018 |
A p300/GATA6 axis determines differentiation and Wnt dependency in pancreatic cancer models Z Zhong, N Harmston, KC Wood, B Madan, DM Virshup The Journal of Clinical Investigation 132 (12), 2022 | 29 | 2022 |
Widespread repression of gene expression in cancer by a Wnt/β-catenin/MAPK pathway N Harmston, JYS Lim, O Arqués, HG Palmer, E Petretto, DM Virshup, ... Cancer Research 81 (2), 464-475, 2021 | 29 | 2021 |
Systems genetics identifies a macrophage cholesterol network associated with physiological wound healing M Bagnati, A Moreno-Moral, JH Ko, J Nicod, N Harmston, M Imprialou, ... JCI insight 4 (2), e125736, 2019 | 19 | 2019 |