Thomas Perls
Thomas Perls
Professor of Medicine, Boston University School of Medicine
Verified email at
Cited by
Cited by
Morbidity profiles of centenarians: survivors, delayers, and escapers
J Evert, E Lawler, H Bogan, T Perls
The Journals of Gerontology Series A: Biological Sciences and Medical …, 2003
A catalog of genetic loci associated with kidney function from analyses of a million individuals
M Wuttke, Y Li, M Li, KB Sieber, MF Feitosa, M Gorski, A Tin, L Wang, ...
Nature genetics 51 (6), 957-972, 2019
Genetic signatures of exceptional longevity in humans
P Sebastiani, N Solovieff, AT DeWan, KM Walsh, A Puca, SW Hartley, ...
PloS one 7 (1), e29848, 2012
Life-long sustained mortality advantage of siblings of centenarians
TT Perls, J Wilmoth, R Levenson, M Drinkwater, M Cohen, H Bogan, ...
Proceedings of the National Academy of Sciences 99 (12), 8442-8447, 2002
Clinical and pathological correlates of apolipoprotein E ε4 in Alzheimer's disease
T Gomez‐Isla, HL West, GW Rebeck, SD Harr, JH Growdon, JJ Locascio, ...
Annals of neurology 39 (1), 62-70, 1996
Achieving and maintaining cognitive vitality with aging
HM Fillit, RN Butler, AW O'Connell, MS Albert, JE Birren, CW Cotman, ...
Mayo Clinic Proceedings 77 (7), 681-696, 2002
A genome-wide scan for linkage to human exceptional longevity identifies a locus on chromosome 4
AA Puca, MJ Daly, SJ Brewster, TC Matise, J Barrett, M Shea-Drinkwater, ...
Proceedings of the National Academy of Sciences 98 (18), 10505-10508, 2001
Health span approximates life span among many supercentenarians: compression of morbidity at the approximate limit of life span
SL Andersen, P Sebastiani, DA Dworkis, L Feldman, TT Perls
Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2012
Centenarians: the older you get, the healthier you have been
R Hitt, Y Young-Xu, M Silver, T Perls
The Lancet 354 (9179), 652, 1999
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels
A Tin, J Marten, VL Halperin Kuhns, Y Li, M Wuttke, H Kirsten, KB Sieber, ...
Nature genetics 51 (10), 1459-1474, 2019
GWAS of Longevity in CHARGE Consortium Confirms APOE and FOXO3 Candidacy
L Broer, AS Buchman, J Deelen, DS Evans, JD Faul, KL Lunetta, ...
Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2015
Middle-aged mothers live longer
TT Perls, L Alpert, RC Fretts
Nature 389 (6647), 133-133, 1997
A meta-analysis of genome-wide association studies identifies multiple longevity genes
J Deelen, DS Evans, DE Arking, N Tesi, M Nygaard, X Liu, MK Wojczynski, ...
Nature communications 10 (1), 3669, 2019
Siblings of centenarians live longer
TT Perls, E Bubrick, CG Wager, J Vijg, L Kruglyak
The Lancet 351 (9115), 1560, 1998
The genetics of exceptional human longevity
T Perls, LM Kunkel, AA Puca
Journal of the American Geriatrics Society 50 (2), 359-368, 2002
Reduced apolipoprotein ϵ4 allele frequency in the oldest old Alzheimer's patients and cognitively normal individuals
GW Rebeck, TT Perls, HL West, P Sodhi, LA Lipsitz, BT Hyman
Neurology 44 (8), 1513-1513, 1994
The genetics of extreme longevity: lessons from the new England centenarian study
P Sebastiani, TT Perls
Frontiers in genetics 3, 277, 2012
Cell-by-cell scanning of whole mitochondrial genomes in aged human heart reveals a significant fraction of myocytes with clonally expanded deletions
K Khrapko, N Bodyak, WG Thilly, NJ Van Orsouw, X Zhang, HA Coller, ...
Nucleic acids research 27 (11), 2434-2441, 1999
Biomarker signatures of aging
P Sebastiani, B Thyagarajan, F Sun, N Schupf, AB Newman, M Montano, ...
Aging cell 16 (2), 329-338, 2017
Health and function of participants in the Long Life Family Study: a comparison with other cohorts
AB Newman, NW Glynn, CA Taylor, P Sebastiani, TT Perls, R Mayeux, ...
Aging (Albany NY) 3 (1), 63, 2011
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