An epithelial–mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor … LA Byers, L Diao, J Wang, P Saintigny, L Girard, M Peyton, L Shen, Y Fan, ... Clinical cancer research 19 (1), 279-290, 2013 | 1009 | 2013 |
Co-occurring Genomic Alterations Define Major Subsets of KRAS-Mutant Lung Adenocarcinoma with Distinct Biology, Immune Profiles, and Therapeutic … F Skoulidis, LA Byers, L Diao, VA Papadimitrakopoulou, P Tong, J Izzo, ... Cancer discovery 5 (8), 860-877, 2015 | 785 | 2015 |
Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1 LA Byers, J Wang, MB Nilsson, J Fujimoto, P Saintigny, J Yordy, U Giri, ... Cancer discovery 2 (9), 798-811, 2012 | 518 | 2012 |
Detection of T790M, the Acquired Resistance EGFR Mutation, by Tumor Biopsy versus Noninvasive Blood-Based Analyses TK Sundaresan, LV Sequist, JV Heymach, GJ Riely, PA Jänne, WH Koch, ... Clinical Cancer Research 22 (5), 1103-1110, 2016 | 382 | 2016 |
TP53 Disruptive Mutations Lead to Head and Neck Cancer Treatment Failure through Inhibition of Radiation-Induced Senescence HD Skinner, VC Sandulache, TJ Ow, RE Meyn, JS Yordy, BM Beadle, ... Clinical cancer research 18 (1), 290-300, 2012 | 320 | 2012 |
KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling KW Wagner, H Alam, SS Dhar, U Giri, N Li, Y Wei, D Giri, T Cascone, ... The Journal of clinical investigation 123 (12), 5231-5246, 2013 | 188 | 2013 |
miRNA expression profiles in head and neck squamous cell carcinoma and adjacent normal tissue L Ramdas, U Giri, CL Ashorn, KR Coombes, A El‐Naggar, KK Ang, ... Head & Neck: Journal for the Sciences and Specialties of the Head and Neck …, 2009 | 170 | 2009 |
Evolutionary action score of TP53 identifies high-risk mutations associated with decreased survival and increased distant metastases in head and neck cancer DM Neskey, AA Osman, TJ Ow, P Katsonis, T McDonald, SC Hicks, ... Cancer research 75 (7), 1527-1536, 2015 | 168 | 2015 |
Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities. Cancer Discov … F Skoulidis, LA Byers, L Diao, VA Papadimitrakopoulou, P Tong, J Izzo, ... External Resources Crossref (DOI), 2012 | 144 | 2012 |
Porphyrin-mediated photosensitization has a weak tumor promoting activity in mouse skin: possible role of in situ-generated reactive oxygen species U Giri, M Iqbal, M Athar Carcinogenesis 17 (9), 2023-2028, 1996 | 122 | 1996 |
Integrative analysis identifies a novel AXL–PI3 Kinase–PD-L1 signaling axis associated with radiation resistance in head and neck cancer HD Skinner, U Giri, LP Yang, M Kumar, Y Liu, MD Story, CR Pickering, ... Clinical Cancer Research 23 (11), 2713-2722, 2017 | 117 | 2017 |
DNA repair biomarker profiling of head and neck cancer: Ku80 expression predicts locoregional failure and death following radiotherapy BJ Moeller, JS Yordy, MD Williams, U Giri, U Raju, DP Molkentine, ... Clinical Cancer Research 17 (7), 2035-2043, 2011 | 110 | 2011 |
Ferric nitrilotriacetate (Fe-NTA) is a potent hepatic tumor promoter and acts through the generation of oxidative stress M Iqbal, U Giri, M Athar Biochemical and biophysical research communications 212 (2), 557-563, 1995 | 80 | 1995 |
Evidence that in situ generated reactive oxygen species act as a potent stage I tumor promoter in mouse skin U Giri, SD Sharma, M Abdulla, M Athar Biochemical and biophysical research communications 209 (2), 698-705, 1995 | 76 | 1995 |
Proteomic profiling identifies PTK2/FAK as a driver of radioresistance in HPV-negative head and neck cancer HD Skinner, U Giri, L Yang, SH Woo, MD Story, CR Pickering, LA Byers, ... Clinical Cancer Research 22 (18), 4643-4650, 2016 | 74 | 2016 |
Increased VEGFR-2 gene copy is associated with chemoresistance and shorter survival in patients with non–small-cell lung carcinoma who receive adjuvant chemotherapy F Yang, X Tang, E Riquelme, C Behrens, MB Nilsson, U Giri, ... Cancer research 71 (16), 5512-5521, 2011 | 74 | 2011 |
In vivo delivery of miR-34a sensitizes lung tumors to radiation through RAD51 regulation MA Cortez, D Valdecanas, S Niknam, HJ Peltier, L Diao, U Giri, R Komaki, ... Molecular Therapy-Nucleic Acids 4, 2015 | 72 | 2015 |
The HGF/c-MET Pathway Is a Driver and Biomarker of VEGFR-inhibitor Resistance and Vascular Remodeling in Non–Small Cell Lung Cancer T Cascone, LI Xu, HY Lin, W Liu, HT Tran, Y Liu, K Howells, V Haddad, ... Clinical Cancer Research 23 (18), 5489-5501, 2017 | 67 | 2017 |
Age-dependent renal accumulation of 4-hydroxy-2-nonenal (HNE)-modified proteins following parenteral administration of ferric nitrilotriacetate commensurate with its … M Iqbal, U Giri, DK Giri, MS Alam, M Athar Archives of Biochemistry and Biophysics 365 (1), 101-112, 1999 | 62 | 1999 |
A novel Chk inhibitor, XL-844, increases human cancer cell radiosensitivity through promotion of mitotic catastrophe O Riesterer, F Matsumoto, L Wang, J Pickett, D Molkentine, U Giri, L Milas, ... Investigational new drugs 29, 514-522, 2011 | 61 | 2011 |