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| High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis S Eyre, J Bowes, D Diogo, A Lee, A Barton, P Martin, A Zhernakova, ... Nature genetics 44 (12), 1336-1340, 2012 | 748 | 2012 |
| FinnGen provides genetic insights from a well-phenotyped isolated population MI Kurki, J Karjalainen, P Palta, TP Sipilä, K Kristiansson, KM Donner, ... Nature 613 (7944), 508-518, 2023 | 730 | 2023 |
| International IBD Genetics Consortium (IIBDGC). Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease L Jostins, S Ripke, RK Weersma, RH Duerr, DP McGovern, KY Hui, ... Nature 491 (7422), 119-124, 2012 | 621 | 2012 |
| Automated high-dimensional flow cytometric data analysis S Pyne, X Hu, K Wang, E Rossin, TI Lin, LM Maier, C Baecher-Allan, ... Proceedings of the National Academy of Sciences 106 (21), 8519-8524, 2009 | 497 | 2009 |
| FinnGen: Unique genetic insights from combining isolated population and national health register data MI Kurki, J Karjalainen, P Palta, TP Sipilä, K Kristiansson, K Donner, ... MedRxiv, 2022.03. 03.22271360, 2022 | 348 | 2022 |
| High-density mapping of the MHC identifies a shared role for HLA-DRB1* 01: 03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis P Goyette, G Boucher, D Mallon, E Ellinghaus, L Jostins, H Huang, ... Nature genetics 47 (2), 172-179, 2015 | 329 | 2015 |
| Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk X Hu, AJ Deutsch, TL Lenz, S Onengut-Gumuscu, B Han, WM Chen, ... Nature genetics 47 (8), 898-905, 2015 | 265 | 2015 |
| The role of the CD58 locus in multiple sclerosis PL De Jager, C Baecher-Allan, LM Maier, AT Arthur, L Ottoboni, ... Proceedings of the National Academy of Sciences 106 (13), 5264-5269, 2009 | 238 | 2009 |
| Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases TL Lenz, AJ Deutsch, B Han, X Hu, Y Okada, S Eyre, M Knapp, ... Nature genetics 47 (9), 1085-1090, 2015 | 204 | 2015 |
| Integrating autoimmune risk loci with gene-expression data identifies specific pathogenic immune cell subsets X Hu, H Kim, E Stahl, R Plenge, M Daly, S Raychaudhuri The American Journal of Human Genetics 89 (4), 496-506, 2011 | 195 | 2011 |
| Disentangling the effects of colocalizing genomic annotations to functionally prioritize non-coding variants within complex-trait loci G Trynka, HJ Westra, K Slowikowski, X Hu, H Xu, BE Stranger, RJ Klein, ... The American Journal of Human Genetics 97 (1), 139-152, 2015 | 142 | 2015 |
| Systematic single-variant and gene-based association testing of thousands of phenotypes in 394,841 UK Biobank exomes KJ Karczewski, M Solomonson, KR Chao, JK Goodrich, G Tiao, W Lu, ... Cell Genomics 2 (9), 2022 | 103 | 2022 |
| A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases B Han, JG Pouget, K Slowikowski, E Stahl, CH Lee, D Diogo, X Hu, ... Nature genetics 48 (7), 803-810, 2016 | 73 | 2016 |
| SNPsea: an algorithm to identify cell types, tissues and pathways affected by risk loci K Slowikowski, X Hu, S Raychaudhuri Bioinformatics 30 (17), 2496-2497, 2014 | 72 | 2014 |
| New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis SH Lee, EM Byrne, CM Hultman, A Kähler, AAE Vinkhuyzen, S Ripke, ... International journal of epidemiology 44 (5), 1706-1721, 2015 | 66 | 2015 |
| Regulation of Gene Expression in Autoimmune Disease Loci and the Genetic Basis of Proliferation in CD4+ Effector Memory T Cells X Hu, H Kim, T Raj, PJ Brennan, G Trynka, N Teslovich, K Slowikowski, ... PLoS genetics 10 (6), e1004404, 2014 | 57 | 2014 |
| IBDGC International, MS Silverberg, V L Jostins, S Ripke, RK Weersma, RH Duerr, DP McGovern, KY Hui, ... Annese, H. Hakonarson, SR Brant, G. Radford-Smith, CG Mathew, JD Rioux, EE …, 2012 | 56 | 2012 |
| What have we learned from six years of GWAS in autoimmune diseases, and what is next? X Hu, M Daly Current opinion in immunology 24 (5), 571-575, 2012 | 44 | 2012 |
| Systematic single-variant and gene-based association testing of thousands of phenotypes in 426,370 UK Biobank exomes KJ Karczewski, M Solomonson, KR Chao, JK Goodrich, G Tiao, W Lu, ... Medrxiv, 2021.06. 19.21259117, 2021 | 26 | 2021 |
Soumya RaychaudhuriHarvard Medical School; Brigham and Women's Hospital, Broad InstituteVerified email at broadinstitute.org
