Sam Maher
Sam Maher
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Investigation of the cytotoxicity of eukaryotic and prokaryotic antimicrobial peptides in intestinal epithelial cells in vitro
S Maher, S McClean
Biochemical pharmacology 71 (9), 1289-1298, 2006
Safety and efficacy of sodium caprate in promoting oral drug absorption: from in vitro to the clinic
S Maher, TW Leonard, J Jacobsen, DJ Brayden
Advanced drug delivery reviews 61 (15), 1427-1449, 2009
Intestinal permeation enhancers for oral peptide delivery
S Maher, RJ Mrsny, DJ Brayden
Advanced drug delivery reviews 106, 277-319, 2016
Overcoming poor permeability: translating permeation enhancers for oral peptide delivery
S Maher, DJ Brayden
Drug Discovery Today: Technologies 9 (2), e113-e119, 2012
A Whey Protein Hydrolysate Promotes Insulinotropic Activity in a Clonal Pancreatic β-Cell Line and Enhances Glycemic Function in ob/ob Mice
C Gaudel, AB Nongonierma, S Maher, S Flynn, M Krause, BA Murray, ...
The Journal of nutrition 143 (7), 1109-1114, 2013
Melittin exhibits necrotic cytotoxicity in gastrointestinal cells which is attenuated by cholesterol
S Maher, S McClean
Biochemical pharmacology 75 (5), 1104-1114, 2008
Oral delivery of macromolecules: rationale underpinning Gastrointestinal Permeation Enhancement Technology (GIPET)
EG Walsh, BE Adamczyk, KB Chalasani, S Maher, EB O’Toole, JS Fox, ...
Therapeutic delivery 2 (12), 1595-1610, 2011
Application of permeation enhancers in oral delivery of macromolecules: an update
S Maher, DJ Brayden, L Casettari, L Illum
Pharmaceutics 11 (1), 41, 2019
Intestinal permeation enhancers for oral delivery of macromolecules: a comparison between salcaprozate sodium (SNAC) and sodium caprate (C10)
C Twarog, S Fattah, J Heade, S Maher, E Fattal, DJ Brayden
Pharmaceutics 11 (2), 78, 2019
Formulation strategies to improve oral peptide delivery
S Maher, B Ryan, A Duffy, DJ Brayden
Pharmaceutical patent analyst 3 (3), 313-336, 2014
Evaluation of intestinal absorption enhancement and local mucosal toxicity of two promoters. I. Studies in isolated rat and human colonic mucosae
S Maher, R Kennelly, VA Bzik, AW Baird, X Wang, D Winter, DJ Brayden
European journal of pharmaceutical sciences 38 (4), 291-300, 2009
Cracking the junction: update on the progress of gastrointestinal absorption enhancement in the delivery of poorly absorbed drugs
S Maher, DJ Brayden, L Feighery, S McClean
Critical Reviews™ in Therapeutic Drug Carrier Systems 25 (2), 2008
Evaluation of alkylmaltosides as intestinal permeation enhancers: comparison between rat intestinal mucosal sheets and Caco-2 monolayers
SB Petersen, G Nolan, S Maher, UL Rahbek, M Guldbrandt, DJ Brayden
European journal of pharmaceutical sciences 47 (4), 701-712, 2012
Systemic delivery of peptides by the oral route: formulation and medicinal chemistry approaches
DJ Brayden, TA Hill, DP Fairlie, S Maher, RJ Mrsny
Advanced drug delivery reviews 157, 2-36, 2020
Restoration of rat colonic epithelium after in situ intestinal instillation of the absorption promoter, sodium caprate
X Wang, S Maher, DJ Brayden
Therapeutic delivery 1 (1), 75-82, 2010
The mycotoxin patulin increases colonic epithelial permeability in vitro
HM Mohan, D Collins, S Maher, EG Walsh, DC Winter, PJ O’Brien, ...
Food and chemical toxicology 50 (11), 4097-4102, 2012
Melittin as an epithelial permeability enhancer I: investigation of its mechanism of action in Caco-2 monolayers
S Maher, L Feighery, DJ Brayden, S McClean
Pharmaceutical research 24 (7), 1336-1345, 2007
Sodium caprate-induced increases in intestinal permeability and epithelial damage are prevented by misoprostol
DJ Brayden, S Maher, B Bahar, E Walsh
European Journal of Pharmaceutics and Biopharmaceutics 94, 194-206, 2015
Chitooligosaccharide elicits acute inflammatory cytokine response through AP-1 pathway in human intestinal epithelial-like (Caco-2) cells
B Bahar, JV O’Doherty, S Maher, J McMorrow, T Sweeney
Molecular immunology 51 (3-4), 283-291, 2012
Evaluation of intestinal absorption and mucosal toxicity using two promoters. II. Rat instillation and perfusion studies
S Maher, X Wang, V Bzik, S McClean, DJ Brayden
European journal of pharmaceutical sciences 38 (4), 301-311, 2009
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