| A DNA methylation reader complex that enhances gene transcription CJ Harris, M Scheibe, SP Wongpalee, W Liu, EM Cornett, RM Vaughan, ... Science 362 (6419), 1182-1186, 2018 | 200 | 2018 |
| Examining the roles of H3K4 methylation states with systematically characterized antibodies RN Shah, AT Grzybowski, EM Cornett, AL Johnstone, BM Dickson, ... Molecular cell 72 (1), 162-177. e7, 2018 | 110 | 2018 |
| Chromatin regulation through ubiquitin and ubiquitin-like histone modifications RM Vaughan, A Kupai, SB Rothbart Trends in biochemical sciences 46 (4), 258-269, 2021 | 61 | 2021 |
| Chromatin structure and its chemical modifications regulate the ubiquitin ligase substrate selectivity of UHRF1 RM Vaughan, BM Dickson, MF Whelihan, AL Johnstone, EM Cornett, ... Proceedings of the National Academy of Sciences 115 (35), 8775-8780, 2018 | 35 | 2018 |
| Comparative biochemical analysis of UHRF proteins reveals molecular mechanisms that uncouple UHRF2 from DNA methylation maintenance RM Vaughan, BM Dickson, EM Cornett, JS Harrison, B Kuhlman, ... Nucleic acids research 46 (9), 4405-4416, 2018 | 31 | 2018 |
| A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity EM Cornett, BM Dickson, K Krajewski, N Spellmon, A Umstead, ... Science advances 4 (11), eaav2623, 2018 | 27 | 2018 |
| A read/write mechanism connects p300 bromodomain function to H2A. Z acetylation Y Colino-Sanguino, EM Cornett, D Moulder, GC Smith, J Hrit, ... Iscience 21, 773-788, 2019 | 22 | 2019 |
| Substrate specificity profiling of histone-modifying enzymes by peptide microarray EM Cornett, BM Dickson, RM Vaughan, S Krishnan, RC Trievel, BD Strahl, ... Methods in enzymology 574, 31-52, 2016 | 20 | 2016 |
| A fluorescent carbapenem for structure function studies of penicillin-binding proteins, β-lactamases, and β-lactam sensors CM June, RM Vaughan, LS Ulberg, RA Bonomo, LA Witucki, DA Leonard Analytical biochemistry 463, 70-74, 2014 | 19 | 2014 |
| A physical basis for quantitative ChIP-sequencing BM Dickson, RL Tiedemann, AA Chomiak, EM Cornett, RM Vaughan, ... Journal of Biological Chemistry 295 (47), 15826-15837, 2020 | 14 | 2020 |
| The finger loop of the SRA domain in the E3 ligase UHRF1 is a regulator of ubiquitin targeting and is required for the maintenance of DNA methylation RM Vaughan, SB Rothbart, BM Dickson Journal of Biological Chemistry 294 (43), 15724-15732, 2019 | 14 | 2019 |
| A trivalent nucleosome interaction by PHIP/BRWD2 is disrupted in neurodevelopmental disorders and cancer MAJ Morgan, IK Popova, A Vaidya, JM Burg, MR Marunde, ... Genes & Development 35 (23-24), 1642-1656, 2021 | 13 | 2021 |
| The histone and non-histone methyllysine reader activities of the UHRF1 tandem Tudor domain are dispensable for the propagation of aberrant DNA methylation patterning in cancer … RM Vaughan, A Kupai, CA Foley, CA Sagum, BM Tibben, HE Eden, ... Epigenetics & chromatin 13, 1-15, 2020 | 13 | 2020 |
| Streamlined quantitative analysis of histone modification abundance at nucleosome-scale resolution with siQ-ChIP version 2.0 BM Dickson, A Kupai, RM Vaughan, SB Rothbart Scientific Reports 13 (1), 7508, 2023 | 3 | 2023 |
| Theoretical and practical refinements of sans spike-in quantitative ChIP-seq with application to p300/CBP inhibition BM Dickson, A Kupai, RM Vaughan, SB Rothbart bioRxiv, 2022.08. 09.503331, 2022 | 3 | 2022 |
| A degenerate peptide library approach to reveal sequence determinants of methyllysine-driven protein interactions A Kupai, RM Vaughan, BM Dickson, SB Rothbart Frontiers in Cell and Developmental Biology 8, 241, 2020 | 3 | 2020 |
| The complex, dynamic SpliceOme of the small GTPase transcripts altered by technique, sex, genetics, tissue specificity, and RNA base editing AS Das, EC Sherry, RM Vaughan, ML Henderson, J Zieba, KL Uhl, ... Frontiers in Cell and Developmental Biology 10, 1033695, 2022 | 2 | 2022 |
| Chemical biology screening identifies a vulnerability to checkpoint kinase inhibitors in TSC2-deficient renal angiomyolipomas RM Vaughan, JJ Kordich, CY Chan, NK Sasi, SL Celano, KA Sisson, ... Frontiers in Oncology 12, 852859, 2022 | 2 | 2022 |
| UHRF1 ubiquitin ligase activity supports the maintenance of low-density CpG methylation R Tiedemann, J Hrit, Q Du, AK Wiseman, HE Eden, BM Dickson, X Kong, ... bioRxiv, 2024.02. 13.580169, 2024 | | 2024 |
| Molecular dynamics simulations provide insights into ULK-101 potency and selectivity toward autophagic kinases ULK1/2 RM Vaughan, BM Dickson, KR Martin, JP MacKeigan Biorxiv, 2023 | | 2023 |
Scott B. RothbartProfessor, Van Andel InstituteVerified email at vai.org
