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Andrew J Steele
Andrew J Steele
Associate Director, Johnson and Johnson
Verified email at soton.ac.uk - Homepage
Title
Cited by
Cited by
Year
B-cell receptor signaling in chronic lymphocytic leukemia
FK Stevenson, S Krysov, AJ Davies, AJ Steele, G Packham
Blood, The Journal of the American Society of Hematology 118 (16), 4313-4320, 2011
4912011
The outcome of B-cell receptor signaling in chronic lymphocytic leukemia: proliferation or anergy
G Packham, S Krysov, A Allen, N Savelyeva, AJ Steele, F Forconi, ...
haematologica 99 (7), 1138, 2014
1452014
Detection of serum reverse transcriptase activity in patients with ALS and unaffected blood relatives
AJ Steele, A Al-Chalabi, K Ferrante, ME Cudkowicz, RH Brown Jr, ...
Neurology 64 (3), 454-458, 2005
1312005
Autophagy inhibition-mediated epithelial–mesenchymal transition augments local myofibroblast differentiation in pulmonary fibrosis
C Hill, J Li, D Liu, F Conforti, CJ Brereton, L Yao, Y Zhou, A Alzetani, ...
Cell death & disease 10 (8), 591, 2019
1272019
IL-4 enhances expression and function of surface IgM in CLL cells
MM Aguilar-Hernandez, MD Blunt, R Dobson, A Yeomans, ...
Blood, The Journal of the American Society of Hematology 127 (24), 3015-3025, 2016
1182016
ATM mutation rather than BIRC3 deletion and/or mutation predicts reduced survival in 11q-deleted chronic lymphocytic leukemia: data from the UK LRF CLL4 trial
MJJ Rose-Zerilli, J Forster, H Parker, A Parker, AE Rodríguez, T Chaplin, ...
haematologica 99 (4), 736, 2014
1142014
Fixed-duration ibrutinib-venetoclax in patients with chronic lymphocytic leukemia and comorbidities
AP Kater, C Owen, C Moreno, G Follows, T Munir, MD Levin, O Benjamini, ...
NEJM evidence 1 (7), EVIDoa2200006, 2022
1112022
The SF3B1 inhibitor spliceostatin A (SSA) elicits apoptosis in chronic lymphocytic leukaemia cells through downregulation of Mcl-1
M Larrayoz, SJ Blakemore, RC Dobson, MD Blunt, MJJ Rose-Zerilli, ...
Leukemia 30 (2), 351-360, 2016
1042016
The sesquiterpene lactone parthenolide induces selective apoptosis of B-chronic lymphocytic leukemia cells in vitro
AJ Steele, DT Jones, K Ganeshaguru, VM Duke, BC Yogashangary, ...
Leukemia 20 (6), 1073-1079, 2006
972006
p53-mediated apoptosis of CLL cells: evidence for a transcription-independent mechanism
AJ Steele, AG Prentice, AV Hoffbrand, BC Yogashangary, SM Hart, ...
Blood, The Journal of the American Society of Hematology 112 (9), 3827-3834, 2008
892008
The JAK3-selective inhibitor PF-956980 reverses the resistance to cytotoxic agents induced by interleukin-4 treatment of chronic lymphocytic leukemia cells: potential for …
AJ Steele, AG Prentice, K Cwynarski, AV Hoffbrand, SM Hart, MW Lowdell, ...
Blood, The Journal of the American Society of Hematology 116 (22), 4569-4577, 2010
862010
Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia
H Parker, MJJ Rose-Zerilli, M Larrayoz, R Clifford, J Edelmann, ...
Leukemia 30 (11), 2179-2186, 2016
802016
Identification in CLL of circulating intraclonal subgroups with varying B-cell receptor expression and function
V Coelho, S Krysov, A Steele, M Sanchez Hidalgo, PW Johnson, ...
Blood, The Journal of the American Society of Hematology 122 (15), 2664-2672, 2013
752013
Selective apoptotic killing of malignant hemopoietic cells by antibody-targeted delivery of an amphipathic peptide
AJ Marks, MS Cooper, RJ Anderson, KH Orchard, G Hale, JM North, ...
Cancer research 65 (6), 2373-2377, 2005
752005
STING activation reverses lymphoma-mediated resistance to antibody immunotherapy
LN Dahal, L Dou, K Hussain, R Liu, A Earley, KL Cox, S Murinello, I Tracy, ...
Cancer research 77 (13), 3619-3631, 2017
742017
p53 and Notch signaling in chronic lymphocytic leukemia: clues to identifying novel therapeutic strategies
RG Wickremasinghe, AG Prentice, AJ Steele
Leukemia 25 (9), 1400-1407, 2011
722011
Surface IgM expression and function are associated with clinical behavior, genetic abnormalities, and DNA methylation in CLL
A D’Avola, S Drennan, I Tracy, I Henderson, L Chiecchio, M Larrayoz, ...
Blood, The Journal of the American Society of Hematology 128 (6), 816-826, 2016
682016
The dual Syk/JAK inhibitor cerdulatinib antagonizes B-cell receptor and microenvironmental signaling in chronic lymphocytic leukemia
MD Blunt, S Koehrer, RC Dobson, M Larrayoz, S Wilmore, A Hayman, ...
Clinical Cancer Research 23 (9), 2313-2324, 2017
662017
Engagement of the B-cell receptor of chronic lymphocytic leukemia cells drives global and MYC-specific mRNA translation
A Yeomans, SM Thirdborough, B Valle-Argos, A Linley, S Krysov, ...
Blood, The Journal of the American Society of Hematology 127 (4), 449-457, 2016
642016
Proteomics profiling of CLL versus healthy B-cells identifies putative therapeutic targets and a subtype-independent signature of spliceosome dysregulation
HE Johnston, MJ Carter, M Larrayoz, J Clarke, SD Garbis, D Oscier, ...
Molecular & Cellular Proteomics 17 (4), 776-791, 2018
582018
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