Amyotrophic lateral sclerosis O Hardiman, A Al-Chalabi, A Chio, EM Corr, G Logroscino, W Robberecht, ... Nature reviews Disease primers 3 (1), 1-19, 2017 | 2019 | 2017 |
Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study E Majounie, AE Renton, K Mok, EGP Dopper, A Waite, S Rollinson, ... The Lancet Neurology 11 (4), 323-330, 2012 | 1383 | 2012 |
Effects of non-invasive ventilation on survival and quality of life in patients with amyotrophic lateral sclerosis: a randomised controlled trial SC Bourke, M Tomlinson, TL Williams, RE Bullock, PJ Shaw, GJ Gibson The Lancet Neurology 5 (2), 140-147, 2006 | 1278 | 2006 |
Pathological TDP‐43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations IRA Mackenzie, EH Bigio, PG Ince, F Geser, M Neumann, NJ Cairns, ... Annals of Neurology: Official Journal of the American Neurological …, 2007 | 1225 | 2007 |
Adaptation to culture of human embryonic stem cells and oncogenesis in vivo DEC Baker, NJ Harrison, E Maltby, K Smith, HD Moore, PJ Shaw, ... Nature biotechnology 25 (2), 207-215, 2007 | 798 | 2007 |
Oxidative stress in ALS: key role in motor neuron injury and therapeutic target SC Barber, PJ Shaw Free Radical Biology and Medicine 48 (5), 629-641, 2010 | 753 | 2010 |
Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis L Ferraiuolo, J Kirby, AJ Grierson, M Sendtner, PJ Shaw Nature Reviews Neurology 7 (11), 616-630, 2011 | 718 | 2011 |
White matter lesions in an unselected cohort of the elderly: molecular pathology suggests origin from chronic hypoperfusion injury MS Fernando, JE Simpson, F Matthews, C Brayne, CE Lewis, R Barber, ... Stroke 37 (6), 1391-1398, 2006 | 672 | 2006 |
Controversies and priorities in amyotrophic lateral sclerosis MR Turner, O Hardiman, M Benatar, BR Brooks, A Chio, M De Carvalho, ... The Lancet Neurology 12 (3), 310-322, 2013 | 654 | 2013 |
Genome-wide analyses identify KIF5A as a novel ALS gene A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ... Neuron 97 (6), 1267-1288, 2018 | 649 | 2018 |
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis W Van Rheenen, A Shatunov, AM Dekker, RL McLaughlin, FP Diekstra, ... Nature genetics 48 (9), 1043-1048, 2016 | 631 | 2016 |
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions VM Van Deerlin, PMA Sleiman, M Martinez-Lage, A Chen-Plotkin, ... Nature genetics 42 (3), 234-239, 2010 | 629 | 2010 |
Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target SC Barber, RJ Mead, PJ Shaw Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1762 (11-12 …, 2006 | 604 | 2006 |
Neurologic and neuropsychological morbidity following major surgery: comparison of coronary artery bypass and peripheral vascular surgery. PJ Shaw, D Bates, NE Cartlidge, JM French, D Heaviside, DG Julian, ... Stroke 18 (4), 700-707, 1987 | 603 | 1987 |
The role of mitochondria in amyotrophic lateral sclerosis EF Smith, PJ Shaw, KJ De Vos Neuroscience letters 710, 132933, 2019 | 560 | 2019 |
ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B) N Parkinson, PG Ince, MO Smith, R Highley, G Skibinski, PM Andersen, ... Neurology 67 (6), 1074-1077, 2006 | 524 | 2006 |
Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS T Miller, M Cudkowicz, PJ Shaw, PM Andersen, N Atassi, RC Bucelli, ... New England Journal of Medicine 383 (2), 109-119, 2020 | 520 | 2020 |
Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS TM Miller, ME Cudkowicz, A Genge, PJ Shaw, G Sobue, RC Bucelli, ... New England Journal of Medicine 387 (12), 1099-1110, 2022 | 508 | 2022 |
Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content KJ De Vos, AL Chapman, ME Tennant, C Manser, EL Tudor, KF Lau, ... Human molecular genetics 16 (22), 2720-2728, 2007 | 501 | 2007 |
Prognosis for patients with amyotrophic lateral sclerosis: development and validation of a personalised prediction model HJ Westeneng, TPA Debray, AE Visser, RPA van Eijk, JPK Rooney, ... The Lancet Neurology 17 (5), 423-433, 2018 | 491 | 2018 |