| Rare missense variants in POT1 predispose to familial cutaneous malignant melanoma J Shi, XR Yang, B Ballew, M Rotunno, D Calista, MC Fargnoli, P Ghiorzo, ... Nature genetics 46 (5), 482-486, 2014 | 347 | 2014 |
| Telomere-end processing: the terminal nucleotidesof human chromosomes AJ Sfeir, W Chai, JW Shay, WE Wright Molecular cell 18 (1), 131-138, 2005 | 298 | 2005 |
| Human Ku70/80 associates physically with telomerase through interaction with hTERT W Chai, LP Ford, L Lenertz, WE Wright, JW Shay Journal of Biological Chemistry 277 (49), 47242-47247, 2002 | 184 | 2002 |
| Mammalian DNA2 helicase/nuclease cleaves G‐quadruplex DNA and is required for telomere integrity W Lin, S Sampathi, H Dai, C Liu, M Zhou, J Hu, Q Huang, J Campbell, ... The EMBO journal 32 (10), 1425-1439, 2013 | 177 | 2013 |
| Human telomeres have different overhang sizes at leading versus lagging strands W Chai, Q Du, JW Shay, WE Wright Molecular cell 21 (3), 427-435, 2006 | 176 | 2006 |
| CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion P Gu, JN Min, Y Wang, C Huang, T Peng, W Chai, S Chang The EMBO journal 31 (10), 2309-2321, 2012 | 171 | 2012 |
| The involvement of the Mre11/Rad50/Nbs1 complex in the generation of G‐overhangs at human telomeres W Chai, AJ Sfeir, H Hoshiyama, JW Shay, WE Wright EMBO reports 7 (2), 225-230, 2006 | 148 | 2006 |
| Mcm10 and Cdc45 cooperate in origin activation in Saccharomyces cerevisiae SL Sawyer, IH Cheng, W Chai, BK Tye Journal of molecular biology 340 (2), 195-202, 2004 | 118 | 2004 |
| Human Stn1 protects telomere integrity by promoting efficient lagging-strand synthesis at telomeres and mediating C-strand fill-in C Huang, X Dai, W Chai Cell research 22 (12), 1681-1695, 2012 | 113 | 2012 |
| Human telomeres maintain their overhang length at senescence W Chai, JW Shay, WE Wright Molecular and cellular biology 25 (6), 2158-2168, 2005 | 110 | 2005 |
| Telomere dynamics in macaques and humans JP Gardner, M Kimura, W Chai, JF Durrani, L Tchakmakjian, X Cao, X Lu, ... The Journals of Gerontology Series A: Biological Sciences and Medical …, 2007 | 109 | 2007 |
| Molecular steps of G‐overhang generation at human telomeres and its function in chromosome end protection X Dai, C Huang, A Bhusari, S Sampathi, K Schubert, W Chai The EMBO journal 29 (16), 2788-2801, 2010 | 86 | 2010 |
| Human CST facilitates genome-wide RAD51 recruitment to GC-rich repetitive sequences in response to replication stress M Chastain, Q Zhou, O Shiva, M Fadri-Moskwik, L Whitmore, P Jia, X Dai, ... Cell reports 16 (5), 1300-1314, 2016 | 85 | 2016 |
| NasR, a novel RNA-binding protein, mediates nitrate-responsive transcription antitermination of the Klebsiella oxytoca M5al nasF operon leader in vitro W Chai, V Stewart Journal of molecular biology 283 (2), 339-351, 1998 | 68 | 1998 |
| DNA excision repair at telomeres P Jia, C Her, W Chai DNA repair 36, 137-145, 2015 | 53 | 2015 |
| RNA sequence requirements for NasR-mediated, nitrate-responsive transcription antitermination of the Klebsiella oxytoca M5al nasF operon leader W Chai, V Stewart Journal of molecular biology 292 (2), 203-216, 1999 | 47 | 1999 |
| General Nitrogen Regulation of Nitrate Assimilation Regulatory Gene nasR Expression in Klebsiella oxytoca M5al SQ Wu, W Chai, JT Lin, V Stewart Journal of bacteriology 181 (23), 7274-7284, 1999 | 45 | 1999 |
| Telomere replication: poised but puzzling S Sampathi, W Chai Journal of cellular and molecular medicine 15 (1), 3-13, 2011 | 39 | 2011 |
| Human flap endonuclease I is in complex with telomerase and is required for telomerase-mediated telomere maintenance S Sampathi, A Bhusari, B Shen, W Chai Journal of biological chemistry 284 (6), 3682-3690, 2009 | 39 | 2009 |
| Pathogenic CTC1 mutations cause global genome instabilities under replication stress Y Wang, W Chai Nucleic acids research 46 (8), 3981-3992, 2018 | 37 | 2018 |
