Ana J. Garcia-Saez
Ana J. Garcia-Saez
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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ...
Cell Death & Differentiation 25 (3), 486-541, 2018
Effect of line tension on the lateral organization of lipid membranes
AJ García-Sáez, S Chiantia, P Schwille
Journal of Biological Chemistry 282 (46), 33537-33544, 2007
The secrets of the Bcl-2 family
AJ Garcia-Saez
Cell Death & Differentiation 19 (11), 1733-1740, 2012
Membrane-insertion fragments of Bcl-xL, Bax, and Bid
AJ García-Sáez, I Mingarro, E Pérez-Payá, J Salgado
Biochemistry 43 (34), 10930-10943, 2004
Bax assembly into rings and arcs in apoptotic mitochondria is linked to membrane pores
R Salvador‐Gallego, M Mund, K Cosentino, J Schneider, J Unsay, ...
The EMBO journal 35 (4), 389-401, 2016
Pore formation by a Bax-derived peptide: effect on the line tension of the membrane probed by AFM
AJ García-Sáez, S Chiantia, J Salgado, P Schwille
Biophysical journal 93 (1), 103-112, 2007
Structural model of active Bax at the membrane
S Bleicken, G Jeschke, C Stegmueller, R Salvador-Gallego, ...
Molecular cell 56 (4), 496-505, 2014
Mitochondrial alterations in apoptosis
K Cosentino, AJ García-Sáez
Chemistry and physics of lipids 181, 62-75, 2014
Membrane promotes tBID interaction with BCLXL
AJ García-Sáez, J Ries, M Orzáez, E Pérez-Payà, P Schwille
Nature structural & molecular biology 16 (11), 1178, 2009
Bax, Bak and beyond—mitochondrial performance in apoptosis
A Peña‐Blanco, AJ García‐Sáez
The FEBS journal 285 (3), 416-431, 2018
Equinatoxin II permeabilizing activity depends on the presence of sphingomyelin and lipid phase coexistence
P Schön, AJ García-Sáez, P Malovrh, K Bacia, G Anderluh, P Schwille
Biophysical journal 95 (2), 691-698, 2008
Fluorescence correlation spectroscopy for the study of membrane dynamics and protein/lipid interactions
AJ García-Sáez, P Schwille
Methods 46 (2), 116-122, 2008
Peptides corresponding to helices 5 and 6 of Bax can independently form large lipid pores
AJ García‐Sáez, M Coraiola, MD Serra, I Mingarro, P Müller, J Salgado
The FEBS journal 273 (5), 971-981, 2006
Proapoptotic Bax and Bak proteins form stable protein-permeable pores of tunable size
S Bleicken, O Landeta, A Landajuela, G Basañez, AJ García-Sáez
Journal of Biological Chemistry 288 (46), 33241-33252, 2013
Bax monomers form dimer units in the membrane that further self-assemble into multiple oligomeric species
Y Subburaj, K Cosentino, M Axmann, E Pedrueza-Villalmanzo, ...
Nature communications 6 (1), 1-11, 2015
Peptides derived from apoptotic Bax and Bid reproduce the poration activity of the parent full-length proteins
AJ García-Sáez, M Coraiola, M Dalla Serra, I Mingarro, G Menestrina, ...
Biophysical journal 88 (6), 3976-3990, 2005
Yeast lipids can phase-separate into micrometer-scale membrane domains
C Klose, CS Ejsing, AJ García-Sáez, HJ Kaiser, JL Sampaio, MA Surma, ...
Journal of Biological Chemistry 285 (39), 30224-30232, 2010
Cardiolipin effects on membrane structure and dynamics
JD Unsay, K Cosentino, Y Subburaj, AJ Garcia-Saez
Langmuir 29 (51), 15878-15887, 2013
Pores formed by Baxα5 relax to a smaller size and keep at equilibrium
G Fuertes, AJ García-Sáez, S Esteban-Martín, D Giménez, ...
Biophysical journal 99 (9), 2917-2925, 2010
Quaternary structure of a G-protein-coupled receptor heterotetramer in complex with G i and G s
G Navarro, A Cordomí, M Zelman-Femiak, M Brugarolas, E Moreno, ...
BMC biology 14 (1), 26, 2016
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