Methionine is a metabolic dependency of tumor-initiating cells Z Wang, LY Yip, JHJ Lee, Z Wu, HY Chew, PKW Chong, CC Teo, ... Nature medicine 25 (5), 825-837, 2019 | 281 | 2019 |
Combined in silico modeling and metabolomics analysis to characterize fed‐batch CHO cell culture S Selvarasu, YS Ho, WPK Chong, NSC Wong, FNK Yusufi, YY Lee, ... Biotechnology and bioengineering 109 (6), 1415-1429, 2012 | 240 | 2012 |
Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma HL Penny, JL Sieow, G Adriani, WH Yeap, P See Chi Ee, B San Luis, ... Oncoimmunology 5 (8), e1191731, 2016 | 223 | 2016 |
Excessive fatty acid oxidation induces muscle atrophy in cancer cachexia T Fukawa, BC Yan-Jiang, JC Min-Wen, ET Jun-Hao, D Huang, CN Qian, ... Nature medicine 22 (6), 666-671, 2016 | 200 | 2016 |
Metabolomics-driven approach for the improvement of Chinese hamster ovary cell growth: overexpression of malate dehydrogenase II WPK Chong, SG Reddy, FNK Yusufi, DY Lee, NSC Wong, CK Heng, ... Journal of biotechnology 147 (2), 116-121, 2010 | 120 | 2010 |
LC‐MS‐based metabolic characterization of high monoclonal antibody‐producing Chinese hamster ovary cells WPK Chong, SH Thng, AP Hiu, DY Lee, ECY Chan, YS Ho Biotechnology and bioengineering 109 (12), 3103-3111, 2012 | 103 | 2012 |
Mammalian systems biotechnology reveals global cellular adaptations in a recombinant CHO cell line FNK Yusufi, M Lakshmanan, YS Ho, BLW Loo, P Ariyaratne, Y Yang, ... Cell systems 4 (5), 530-542. e6, 2017 | 101 | 2017 |
Advances in sample preparation and analytical techniques for lipidomics study of clinical samples CC Teo, WPK Chong, E Tan, NB Basri, ZJ Low, YS Ho TrAC Trends in Analytical Chemistry 66, 1-18, 2015 | 98 | 2015 |
Metabolomics profiling of extracellular metabolites in recombinant Chinese Hamster Ovary fed‐batch culture WPK Chong, LT Goh, SG Reddy, FNK Yusufi, DY Lee, NSC Wong, ... Rapid Communications in Mass Spectrometry 23 (23), 3763-3771, 2009 | 91 | 2009 |
Maternal factor NELFA drives a 2C-like state in mouse embryonic stem cells Z Hu, DEK Tan, G Chia, H Tan, HF Leong, BJ Chen, MS Lau, KYS Tan, ... Nature cell biology 22 (2), 175-186, 2020 | 81 | 2020 |
Mitochondrial uncoupling reveals a novel therapeutic opportunity for p53-defective cancers R Kumar, L Coronel, B Somalanka, A Raju, OA Aning, O An, YS Ho, ... Nature communications 9 (1), 3931, 2018 | 74 | 2018 |
Metabolomics-based identification of apoptosis-inducing metabolites in recombinant fed-batch CHO culture media WPK Chong, FNK Yusufi, DY Lee, SG Reddy, NSC Wong, CK Heng, ... Journal of biotechnology 151 (2), 218-224, 2011 | 73 | 2011 |
Comparative study of commercially available polymeric and microporous silica membranes for the dehydration of IPA/water mixtures by pervaporation/vapour permeation T Gallego-Lizon, YS Ho, LF dos Santos Desalination 149 (1-3), 3-8, 2002 | 68 | 2002 |
Development and application of microwave-assisted extraction technique in biological sample preparation for small molecule analysis CC Teo, WPK Chong, YS Ho Metabolomics 9, 1109-1128, 2013 | 56 | 2013 |
Auroramycin: A Potent Antibiotic from Streptomyces roseosporus by CRISPR‐Cas9 Activation YH Lim, FT Wong, WL Yeo, KC Ching, YW Lim, E Heng, S Chen, DJ Tsai, ... ChemBioChem 19 (16), 1716-1719, 2018 | 50 | 2018 |
Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer SY Loo, LP Toh, WH Xie, E Pathak, W Tan, S Ma, MY Lee, ... Science Advances 7 (41), eabh2443, 2021 | 49 | 2021 |
Multi‐omics profiling of CHO parental hosts reveals cell line‐specific variations in bioprocessing traits M Lakshmanan, YJ Kok, AP Lee, S Kyriakopoulos, HL Lim, G Teo, SL Poh, ... Biotechnology and bioengineering 116 (9), 2117-2129, 2019 | 46 | 2019 |
Direct identification of A-to-I editing sites with nanopore native RNA sequencing TA Nguyen, JWJ Heng, P Kaewsapsak, EPL Kok, D Stanojević, H Liu, ... Nature methods 19 (7), 833-844, 2022 | 42 | 2022 |
Development and analysis of a mathematical model for antibody‐producing GS‐NS0 cells under normal and hyperosmotic culture conditions Y Ho, J Varley, A Mantalaris Biotechnology progress 22 (6), 1560-1569, 2006 | 39 | 2006 |
Evaluation and use of disaccharides as energy source in protein-free mammalian cell cultures DSZ Leong, JGL Tan, CL Chin, SY Mak, YS Ho, SK Ng Scientific reports 7 (1), 45216, 2017 | 35 | 2017 |