Truncations of titin causing dilated cardiomyopathy DS Herman, L Lam, MRG Taylor, L Wang, P Teekakirikul, ... New England Journal of Medicine 366 (7), 619-628, 2012 | 1531 | 2012 |
Alterations in sarcoplasmic reticulum gene expression in human heart failure. A possible mechanism for alterations in systolic and diastolic properties of the failing myocardium. M Arai, NR Alpert, DH MacLennan, P Barton, M Periasamy Circulation research 72 (2), 463-469, 1993 | 634 | 1993 |
The translational landscape of the human heart S van Heesch, F Witte, V Schneider-Lunitz, JF Schulz, E Adami, AB Faber, ... Cell 178 (1), 242-260. e29, 2019 | 509 | 2019 |
Developmental regulation of myosin gene expression in mouse cardiac muscle. GE Lyons, S Schiaffino, D Sassoon, P Barton, M Buckingham The Journal of cell biology 111 (6), 2427-2436, 1990 | 506 | 1990 |
Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease AM Roberts, JS Ware, DS Herman, S Schafer, J Baksi, AG Bick, ... Science translational medicine 7 (270), 270ra6-270ra6, 2015 | 493 | 2015 |
Using high-resolution variant frequencies to empower clinical genome interpretation N Whiffin, E Minikel, R Walsh, AH O’Donnell-Luria, K Karczewski, AY Ing, ... Genetics in Medicine 19 (10), 1151-1158, 2017 | 445 | 2017 |
A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy E Villard, C Perret, F Gary, C Proust, G Dilanian, C Hengstenberg, ... European heart journal 32 (9), 1065-1076, 2011 | 383 | 2011 |
Troponin I gene expression during human cardiac development and in end-stage heart failure. S Sasse, NJ Brand, P Kyprianou, GK Dhoot, R Wade, M Arai, ... Circulation research 72 (5), 932-938, 1993 | 329 | 1993 |
Localization of human immunoglobulin kappa light chain variable region genes to the short arm of chromosome 2 by in situ hybridization. S Malcolm, P Barton, C Murphy, MA Ferguson-Smith, DL Bentley, ... Proceedings of the National Academy of Sciences 79 (16), 4957-4961, 1982 | 316 | 1982 |
Titin-truncating variants affect heart function in disease cohorts and the general population S Schafer, A De Marvao, E Adami, LR Fiedler, B Ng, E Khin, ... Nature genetics 49 (1), 46-53, 2017 | 314 | 2017 |
Genetic variants associated with cancer therapy–induced cardiomyopathy P Garcia-Pavia, Y Kim, MA Restrepo-Cordoba, IG Lunde, H Wakimoto, ... Circulation 140 (1), 31-41, 2019 | 282 | 2019 |
Hyperubiquitination of proteins in dilated cardiomyopathy J Weekes, K Morrison, A Mullen, R Wait, P Barton, MJ Dunn Proteomics 3 (2), 208-216, 2003 | 272 | 2003 |
Genetic etiology for alcohol-induced cardiac toxicity JS Ware, A Amor-Salamanca, U Tayal, R Govind, I Serrano, ... Journal of the American College of Cardiology 71 (20), 2293-2302, 2018 | 266 | 2018 |
Molecular cloning of human cardiac troponin I using polymerase chain reaction WJ Vallins, NJ Brand, N Dabhade, G Butler-Browne, MH Yacoub, ... FEBS letters 270 (1-2), 57-61, 1990 | 259 | 1990 |
The myosin alkali light chain proteins and their genes. PJ Barton, ME Buckingham Biochemical Journal 231 (2), 249, 1985 | 243 | 1985 |
Direct intramyocardial but not intracoronary injection of bone marrow cells induces ventricular arrhythmias in a rat chronic ischemic heart failure model S Fukushima, A Varela-Carver, SR Coppen, K Yamahara, LE Felkin, ... Circulation 115 (17), 2254-2261, 2007 | 237 | 2007 |
Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect R Tadros, C Francis, X Xu, AMC Vermeer, AR Harper, R Huurman, ... Nature genetics 53 (2), 128-134, 2021 | 220 | 2021 |
RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing H Maatz, M Jens, M Liss, S Schafer, M Heinig, M Kirchner, E Adami, ... The Journal of clinical investigation 124 (8), 3419-3430, 2014 | 220 | 2014 |
A conserved family of genes related to the testis determining gene, SRY. P Denny, S Swift, N Brand, N Dabhade, P Barton, A Ashworth Nucleic Acids Research 20 (11), 2887, 1992 | 215 | 1992 |
Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathy AK Arndt, S Schafer, JD Drenckhahn, MK Sabeh, ER Plovie, A Caliebe, ... The American Journal of Human Genetics 93 (1), 67-77, 2013 | 214 | 2013 |