The nuclear receptor REV-ERBα mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines JE Gibbs, J Blaikley, S Beesley, L Matthews, KD Simpson, SH Boyce, ... Proceedings of the National Academy of Sciences 109 (2), 582-587, 2012 | 634 | 2012 |
An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action J Gibbs, L Ince, L Matthews, J Mei, T Bell, N Yang, B Saer, N Begley, ... Nature medicine 20 (8), 919-926, 2014 | 404 | 2014 |
Current concepts in glucocorticoid resistance N Yang, DW Ray, LC Matthews Steroids 77 (11), 1041-1049, 2012 | 121 | 2012 |
Caveolin mediates rapid glucocorticoid effects and couples glucocorticoid action to the antiproliferative program L Matthews, A Berry, V Ohanian, J Ohanian, H Garside, D Ray Molecular endocrinology 22 (6), 1320-1330, 2008 | 115 | 2008 |
miR-145 suppresses embryo-epithelial juxtacrine communication at implantation by modulating maternal IGF1R YJ Kang, M Lees, LC Matthews, SJ Kimber, KFJD Aplin Journal of Cell Science 124, 804-814, 2015 | 104 | 2015 |
REVERBa couples the circadian clock to hepatic glucocorticoid action G Caratti, M Iqbal, L Hunter, D Kim, P Wang, RM Vonslow, N Begley, ... The Journal of clinical investigation 128 (10), 4454-4471, 2018 | 77 | 2018 |
Glucocorticoid receptor function in health and disease G Caratti, L Matthews, T Poolman, S Kershaw, M Baxter, D Ray Clinical Endocrinology, 2015 | 65 | 2015 |
Glucocorticoid receptor regulates accurate chromosome segregation and is associated with malignancy L Matthews, A Berry, D Morgan, T Poolman, K Bauer, F Kramer, D Spiller, ... Proceedings of the National Academy of Sciences 112, 5479-5484, 2015 | 60 | 2015 |
Thiazolidinediones are partial agonists for the glucocorticoid receptor L Matthews, A Berry, M Tersigni, F D'Acquisto, A Ianaro, D Ray Endocrinology 150 (1), 75-86, 2009 | 58 | 2009 |
Glucocorticoids promote von hippel lindau degradation and hif-1α stabilization A Vettori, D Greenald, GK Wilson, M Peron, N Facchinello, E Markham, ... Proceedings of the National Academy of Sciences 114 (37), 9948-9953, 2017 | 51 | 2017 |
Glucocorticoid receptor isoforms direct distinct mitochondrial programs to regulate ATP production DJ Morgan, TM Poolman, AJK Williamson, Z Wang, NR Clark, A Ma’ayan, ... Scientific reports 6 (1), 26419, 2016 | 50 | 2016 |
The methyltransferase WBSCR22/Merm1 enhances glucocorticoid receptor function and is regulated in lung inflammation and cancer M Jangani, TM Poolman, L Matthews, N Yang, SN Farrow, A Berry, ... Journal of Biological Chemistry 289 (13), 8931-8946, 2014 | 49 | 2014 |
Loss of glucocorticoid receptor expression by DNA methylation prevents glucocorticoid induced apoptosis in human small cell lung cancer cells P Kay, G Schlossmacher, L Matthews, P Sommer, D Singh, A White, ... PLoS one 6 (10), e24839, 2011 | 49 | 2011 |
Cell cycle phase regulates glucocorticoid receptor function L Matthews, J Johnson, A Berry, P Trebble, A Cookson, D Spiller, ... PLoS One 6 (7), e22289, 2011 | 41 | 2011 |
Circadian variation in pulmonary inflammatory responses is independent of rhythmic glucocorticoid signaling in airway epithelial cells LM Ince, Z Zhang, S Beesley, RM Vonslow, BR Saer, LC Matthews, ... The FASEB Journal 33 (1), 126, 2019 | 40 | 2019 |
Modulation of caveolin-1 expression can affect signalling through the phosphatidylinositol 3-kinase/Akt pathway and cellular proliferation in response to insulin-like growth … LC Matthews, MJ Taggart, M Westwood Endocrinology 149 (10), 5199-5208, 2008 | 36 | 2008 |
Effect of cholesterol depletion on mitogenesis and survival: the role of caveolar and noncaveolar domains in insulin-like growth factor-mediated cellular function LC Matthews, MJ Taggart, M Westwood Endocrinology 146 (12), 5463-5473, 2005 | 33 | 2005 |
Familial glucocorticoid resistance caused by a novel frameshift glucocorticoid receptor mutation P Trebble, L Matthews, J Blaikley, AWO Wayte, GCM Black, A Wilton, ... The Journal of Clinical Endocrinology & Metabolism 95 (12), E490-E499, 2010 | 31 | 2010 |
A ligand-specific kinetic switch regulates glucocorticoid receptor trafficking and function PJ Trebble, JM Woolven, KA Saunders, KD Simpson, SN Farrow, ... Journal of Cell Science 126 (14), 3159-3169, 2013 | 25 | 2013 |
Pin1 promotes GR transactivation by enhancing recruitment to target genes TM Poolman, SN Farrow, L Matthews, AS Loudon, DW Ray Nucleic acids research 41 (18), 8515-8525, 2013 | 23 | 2013 |