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X. WillIam Yang
X. WillIam Yang
Professor, Dept. Psychiatry & Semel Institute, David Geffen School of Medicine at UCLA
Verified email at mednet.ucla.edu - Homepage
Title
Cited by
Cited by
Year
Homologous recombination based modification in Esherichia coli and germline transmission in transgenic mice of a bacterial artificial chromsome
XW Yang, P Model, N Heintz
Nature biotechnology 15 (9), 859-865, 1997
7661997
Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice
M Gray, DI Shirasaki, C Cepeda, VM André, B Wilburn, XH Lu, J Tao, ...
Journal of Neuroscience 28 (24), 6182-6195, 2008
7362008
FACS-array profiling of striatal projection neuron subtypes in juvenile and adult mouse brains
MK Lobo, SL Karsten, M Gray, DH Geschwind, XW Yang
Nature neuroscience 9 (3), 443-452, 2006
4802006
The mouse cortico-striatal projectome
H Hintiryan, NN Foster, I Bowman, M Bay, MY Song, L Gou, S Yamashita, ...
Nature neuroscience 19 (8), 1100-1114, 2016
4492016
Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets
M Jiang, J Wang, J Fu, L Du, H Jeong, T West, L Xiang, Q Peng, Z Hou, ...
Nature medicine 18 (1), 153-158, 2012
3652012
Integrated genomics and proteomics define huntingtin CAG length–dependent networks in mice
P Langfelder, JP Cantle, D Chatzopoulou, N Wang, F Gao, I Al-Ramahi, ...
Nature neuroscience 19 (4), 623-633, 2016
3632016
Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models
L Menalled, BF El-Khodor, M Patry, M Suárez-Fariñas, SJ Orenstein, ...
Neurobiology of disease 35 (3), 319-336, 2009
3632009
Exogenous and evoked oxytocin restores social behavior in the Cntnap2 mouse model of autism
O Peñagarikano, MT Lázaro, XH Lu, A Gordon, H Dong, HA Lam, E Peles, ...
Science translational medicine 7 (271), 271ra8-271ra8, 2015
3612015
Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice
X Gu, ER Greiner, R Mishra, R Kodali, A Osmand, S Finkbeiner, ...
Neuron 64 (6), 828-840, 2009
3542009
Network organization of the huntingtin proteomic interactome in mammalian brain
DI Shirasaki, ER Greiner, I Al-Ramahi, M Gray, P Boontheung, ...
Neuron 75 (1), 41-57, 2012
3202012
Elevated TREM2 gene dosage reprograms microglia responsivity and ameliorates pathological phenotypes in Alzheimer’s disease models
CYD Lee, A Daggett, X Gu, LL Jiang, P Langfelder, X Li, N Wang, Y Zhao, ...
Neuron 97 (5), 1032-1048. e5, 2018
3062018
Assembly and function of heterotypic ubiquitin chains in cell-cycle and protein quality control
RG Yau, K Doerner, ER Castellanos, DL Haakonsen, A Werner, N Wang, ...
Cell 171 (4), 918-933. e20, 2017
2812017
Highly efficient modification of bacterial artificial chromosomes (BACs) using novel shuttle vectors containing the R6Kγ origin of replication
S Gong, XW Yang, C Li, N Heintz
Genome research 12 (12), 1992-1998, 2002
2682002
A multimodal cell census and atlas of the mammalian primary motor cortex
Principal manuscript editors, Analysis coordination, ...
Nature 598 (7879), 86-102, 2021
2622021
Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice
X Gu, C Li, W Wei, V Lo, S Gong, SH Li, T Iwasato, S Itohara, XJ Li, I Mody, ...
Neuron 46 (3), 433-444, 2005
2532005
Conditions and constraints for astrocyte calcium signaling in the hippocampal mossy fiber pathway
MD Haustein, S Kracun, XH Lu, T Shih, O Jackson-Weaver, X Tong, J Xu, ...
Neuron 82 (2), 413-429, 2014
2522014
Identifying polyglutamine protein species in situ that best predict neurodegeneration
J Miller, M Arrasate, E Brooks, CP Libeu, J Legleiter, D Hatters, J Curtis, ...
Nature chemical biology 7 (12), 925-934, 2011
2322011
Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels
S Horvath, P Langfelder, S Kwak, J Aaronson, J Rosinski, TF Vogt, ...
Aging (Albany NY) 8 (7), 1485, 2016
2192016
Morphological diversity of single neurons in molecularly defined cell types
H Peng, P Xie, L Liu, X Kuang, Y Wang, L Qu, H Gong, S Jiang, A Li, ...
Nature 598 (7879), 174-181, 2021
2052021
Bacterial artificial chromosome transgenic mice expressing a truncated mutant Parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and …
XH Lu, SM Fleming, B Meurers, LC Ackerson, F Mortazavi, V Lo, ...
Journal of Neuroscience 29 (7), 1962-1976, 2009
2052009
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