Sec6l-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction EJHJ Wiertz, D Tortorella, M Bogyo, J Yu, W Mothes, TR Jones, ... Nature 384 (6608), 432-438, 1996 | 1448 | 1996 |
The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol EJHJ Wiertz, TR Jones, L Sun, M Bogyo, HJ Geuze, HL Ploegh Cell 84 (5), 769-779, 1996 | 1394 | 1996 |
Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis JA Joyce, A Baruch, K Chehade, N Meyer-Morse, E Giraudo, FY Tsai, ... Cancer cell 5 (5), 443-453, 2004 | 760 | 2004 |
Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools D Greenbaum, KF Medzihradszky, A Burlingame, M Bogyo Chemistry & biology 7 (8), 569-581, 2000 | 730 | 2000 |
Covalent modification of the active site threonine of proteasomal β subunits and the Escherichia coli homolog HslV by a new class of inhibitors M Bogyo, JS McMaster, M Gaczynska, D Tortorella, AL Goldberg, ... Proceedings of the National Academy of Sciences 94 (13), 6629-6634, 1997 | 588 | 1997 |
Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes G Blum, G Von Degenfeld, MJ Merchant, HM Blau, M Bogyo Nature chemical biology 3 (10), 668-677, 2007 | 515 | 2007 |
Substrate profiling of cysteine proteases using a combinatorial peptide library identifies functionally unique specificities Y Choe, F Leonetti, DC Greenbaum, F Lecaille, M Bogyo, D Bromme, ... Journal of Biological Chemistry 281 (18), 12824-12832, 2006 | 505 | 2006 |
A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor B Goulet, A Baruch, NS Moon, M Poirier, LL Sansregret, A Erickson, ... Molecular cell 14 (2), 207-219, 2004 | 449 | 2004 |
Ferri-liposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment G Mikhaylov, U Mikac, AA Magaeva, VI Itin, EP Naiden, I Psakhye, ... Nature nanotechnology 6 (9), 594-602, 2011 | 436 | 2011 |
Tumor cell–derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer O Vasiljeva, A Papazoglou, A Krüger, H Brodoefel, M Korovin, ... Cancer research 66 (10), 5242-5250, 2006 | 426 | 2006 |
Dynamic imaging of protease activity with fluorescently quenched activity-based probes G Blum, SR Mullins, K Keren, M Fonovič, C Jedeszko, MJ Rice, BF Sloane, ... Nature chemical biology 1 (4), 203-209, 2005 | 406 | 2005 |
Activity-based probes that target diverse cysteine protease families D Kato, KM Boatright, AB Berger, T Nazif, G Blum, C Ryan, KAH Chehade, ... Nature chemical biology 1 (1), 33-38, 2005 | 393 | 2005 |
Chemical approaches for functionally probing the proteome D Greenbaum, A Baruch, L Hayrapetian, Z Darula, A Burlingame, ... Molecular & Cellular Proteomics 1 (1), 60-68, 2002 | 388 | 2002 |
Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase SE Ewald, A Engel, J Lee, M Wang, M Bogyo, GM Barton Journal of Experimental Medicine 208 (4), 643-651, 2011 | 367 | 2011 |
Activity-based profiling of proteases LE Sanman, M Bogyo Annual review of biochemistry 83 (1), 249-273, 2014 | 362 | 2014 |
A role for the protease falcipain 1 in host cell invasion by the human malaria parasite DC Greenbaum, A Baruch, M Grainger, Z Bozdech, KF Medzihradszky, ... Science 298 (5600), 2002-2006, 2002 | 360 | 2002 |
Chemical proteomics and its application to drug discovery DA Jeffery, M Bogyo Current opinion in biotechnology 14 (1), 87-95, 2003 | 343 | 2003 |
A proteolytic system that compensates for loss of proteasome function R Glas, M Bogyo, JS McMaster, M Gaczynska, HL Ploegh Nature 392 (6676), 618-622, 1998 | 337 | 1998 |
Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes LE Edgington, AB Berger, G Blum, VE Albrow, MG Paulick, N Lineberry, ... Nature medicine 15 (8), 967-973, 2009 | 332 | 2009 |
Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum S Arastu-Kapur, EL Ponder, UP Fonović, S Yeoh, F Yuan, M Fonović, ... Nature chemical biology 4 (3), 203-213, 2008 | 325 | 2008 |