Complement inhibitor of C5 activation from the soft tick Ornithodoros moubata MA Nunn, A Sharma, GC Paesen, S Adamson, O Lissina, AC Willis, ... The Journal of Immunology 174 (4), 2084-2091, 2005 | 252 | 2005 |
The British river of the future: how climate change and human activity might affect two contrasting river ecosystems in England AC Johnson, MC Acreman, MJ Dunbar, SW Feist, AM Giacomello, ... Science of the Total Environment 407 (17), 4787-4798, 2009 | 177 | 2009 |
Modelling the effect of temperature on the seasonal population dynamics of temperate mosquitoes DA Ewing, CA Cobbold, BV Purse, MA Nunn, SM White Journal of theoretical biology 400, 65-79, 2016 | 175 | 2016 |
Structure of and influence of a tick complement inhibitor on human complement component 5 F Fredslund, NS Laursen, P Roversi, L Jenner, CLP Oliveira, JS Pedersen, ... Nature immunology 9 (7), 753-760, 2008 | 166 | 2008 |
Potential risks associated with the proposed widespread use of Tamiflu AC Singer, MA Nunn, EA Gould, AC Johnson Environmental Health Perspectives 115 (1), 102-106, 2007 | 138 | 2007 |
Structural basis for therapeutic inhibition of complement C5 MM Jore, S Johnson, D Sheppard, NM Barber, YI Li, MA Nunn, H Elmlund, ... Nature structural & molecular biology 23 (5), 378-386, 2016 | 118 | 2016 |
In vivo characterization and therapeutic efficacy of a C5-specific inhibitor from the soft tick Ornithodoros moubata NJ Hepburn, AS Williams, MA Nunn, JC Chamberlain-Banoub, J Hamer, ... Journal of biological chemistry 282 (11), 8292-8299, 2007 | 118 | 2007 |
Complement C5 activation during influenza A infection in mice contributes to neutrophil recruitment and lung injury CC Garcia, W Weston-Davies, RC Russo, LP Tavares, MA Rachid, ... PloS one 8 (5), e64443, 2013 | 104 | 2013 |
Crystal structure and functional characterization of an immunomodulatory salivary cystatin from the soft tick Ornithodoros moubata J Salát, GC Paesen, P Řezáčová, M Kotsyfakis, Z Kovářová, M Šanda, ... Biochemical Journal 429 (1), 103-112, 2010 | 89 | 2010 |
West Nile virus vector Culex modestus established in southern England N Golding, MA Nunn, JM Medlock, BV Purse, AGC Vaux, SM Schäfer Parasites & vectors 5, 1-5, 2012 | 87 | 2012 |
Novel immunomodulators from hard ticks selectively reprogramme human dendritic cell responses SG Preston, J Majtán, C Kouremenou, O Rysnik, LF Burger, ... PLoS pathogens 9 (6), e1003450, 2013 | 80 | 2013 |
Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice M Huber-Lang, A Barratt-Due, SE Pischke, Ø Sandanger, PH Nilsson, ... The Journal of Immunology 192 (11), 5324-5331, 2014 | 72 | 2014 |
The structure of OMCI, a novel lipocalin inhibitor of the complement system P Roversi, O Lissina, S Johnson, N Ahmat, GC Paesen, K Ploss, ... Journal of molecular biology 369 (3), 784-793, 2007 | 69 | 2007 |
Meeting report: risk assessment of Tamiflu use under pandemic conditions AC Singer, BM Howard, AC Johnson, CJ Knowles, S Jackman, C Accinelli, ... Environmental health perspectives 116 (11), 1563-1567, 2008 | 61 | 2008 |
Ornithodoros moubata complement inhibitor is an equally effective C5 inhibitor in pigs and humans A Barratt-Due, EB Thorgersen, JK Lindstad, A Pharo, O Lissina, ... The Journal of Immunology 187 (9), 4913-4919, 2011 | 60 | 2011 |
Vasotab, a vasoactive peptide from horse fly Hybomitra bimaculata (Diptera, Tabanidae) salivary glands P Takác, MA Nunn, J Mészáros, O Pechánová, N Vrbjar, P Vlasáková, ... Journal of experimental biology 209 (2), 343-352, 2006 | 57 | 2006 |
Combined inhibition of complement (C5) and CD14 markedly attenuates inflammation, thrombogenicity, and hemodynamic changes in porcine sepsis A Barratt-Due, EB Thorgersen, K Egge, S Pischke, A Sokolov, ... The Journal of Immunology 191 (2), 819-827, 2013 | 56 | 2013 |
Identifying biotic interactions which drive the spatial distribution of a mosquito community N Golding, MA Nunn, BV Purse Parasites & vectors 8, 1-10, 2015 | 54 | 2015 |
Bifunctional lipocalin ameliorates murine immune complex-induced acute lung injury P Roversi, B Ryffel, D Togbe, I Maillet, M Teixeira, N Ahmat, GC Paesen, ... Journal of Biological Chemistry 288 (26), 18789-18802, 2013 | 54 | 2013 |
An ion-channel modulator from the saliva of the brown ear tick has a highly modified Kunitz/BPTI structure GC Paesen, C Siebold, ML Dallas, C Peers, K Harlos, PA Nuttall, ... Journal of molecular biology 389 (4), 734-747, 2009 | 53 | 2009 |