|Shiga toxin activates complement and binds factor H: evidence for an active role of complement in hemolytic uremic syndrome|
D Orth, AB Khan, A Naim, K Grif, J Brockmeyer, H Karch, M Joannidis, ...
The Journal of Immunology 182 (10), 6394-6400, 2009
|Structural basis for complement factor H–linked age-related macular degeneration|
BE Prosser, S Johnson, P Roversi, AP Herbert, BS Blaum, J Tyrrell, ...
The Journal of experimental medicine 204 (10), 2277-2283, 2007
|Impaired binding of the age-related macular degeneration-associated complement factor H 402H allotype to Bruch's membrane in human retina|
SJ Clark, R Perveen, S Hakobyan, BP Morgan, RB Sim, PN Bishop, ...
Journal of Biological Chemistry 285 (39), 30192-30202, 2010
|His-384 allotypic variant of factor H associated with age-related macular degeneration has different heparin binding properties from the non-disease-associated form|
SJ Clark, VA Higman, B Mulloy, SJ Perkins, SM Lea, RB Sim, AJ Day
Journal of biological chemistry 281 (34), 24713-24720, 2006
|Tissue-specific host recognition by complement factor H is mediated by differential activities of its glycosaminoglycan-binding regions|
SJ Clark, LA Ridge, AP Herbert, S Hakobyan, B Mulloy, R Lennon, ...
The Journal of Immunology 190 (5), 2049-2057, 2013
|Complement factor H in host defense and immune evasion|
R Parente, SJ Clark, A Inforzato, AJ Day
Cellular and Molecular Life Sciences 74, 1605-1624, 2017
|Shift from coral to macroalgae dominance on a volcanically acidified reef|
IC Enochs, DP Manzello, EM Donham, G Kolodziej, R Okano, L Johnston, ...
Nature Climate Change 5 (12), 1083-1088, 2015
|Age-related macular degeneration: genome-wide association studies to translation|
JRM Black, SJ Clark
Genetics in Medicine 18 (4), 283-289, 2016
|The factor H variant associated with age-related macular degeneration (His-384) and the non-disease-associated form bind differentially to C-reactive protein, fibromodulin, DNA …|
AP Sjoberg, LA Trouw, SJ Clark, J Sjolander, D Heinegard, RB Sim, ...
Journal of Biological Chemistry 282 (15), 10894-10900, 2007
|Age-related macular degeneration and the role of the complement system|
S McHarg, SJ Clark, AJ Day, PN Bishop
Molecular immunology 67 (1), 43-50, 2015
|Genetic variants in the complement system predisposing to age-related macular degeneration: a review|
EC Schramm, SJ Clark, MP Triebwasser, S Raychaudhuri, JM Seddon, ...
Molecular immunology 61 (2), 118-125, 2014
|Identification of factor H–like protein 1 as the predominant complement regulator in Bruch’s membrane: Implications for age-related macular degeneration|
SJ Clark, CQ Schmidt, AM White, S Hakobyan, BP Morgan, PN Bishop
The Journal of Immunology 193 (10), 4962-4970, 2014
|Mapping the differential distribution of glycosaminoglycans in the adult human retina, choroid, and sclera|
SJ Clark, TDL Keenan, HL Fielder, LJ Collinson, RJ Holley, CLR Merry, ...
Investigative ophthalmology & visual science 52 (9), 6511-6521, 2011
|Complement factor H and age-related macular degeneration: the role of glycosaminoglycan recognition in disease pathology|
SJ Clark, PN Bishop, AJ Day
Biochemical Society Transactions 38 (5), 1342-1348, 2010
|The eye as a complement dysregulation hotspot|
SJ Clark, PN Bishop
Seminars in immunopathology 40 (1), 65-74, 2018
|The complement system in age-related macular degeneration|
A Armento, M Ueffing, SJ Clark
Cellular and Molecular Life Sciences 78, 4487-4505, 2021
|Complementing the sugar code: role of GAGs and sialic acid in complement regulation|
A Langford-Smith, AJ Day, PN Bishop, SJ Clark
Frontiers in immunology 6, 25, 2015
|Mapping the differential distribution of proteoglycan core proteins in the adult human retina, choroid, and sclera|
TDL Keenan, SJ Clark, RD Unwin, LA Ridge, AJ Day, PN Bishop
Investigative ophthalmology & visual science 53 (12), 7528-7538, 2012
|Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration|
V Cipriani, L Lorés-Motta, F He, D Fathalla, V Tilakaratna, S McHarg, ...
Nature communications 11 (1), 778, 2020
|A method for the non-covalent immobilization of heparin to surfaces|
DJ Mahoney, JD Whittle, CM Milner, SJ Clark, B Mulloy, DJ Buttle, ...
Analytical biochemistry 330 (1), 123-129, 2004