Saverio Tardito
Saverio Tardito
Beatson Institute -Cancer Research UK, Glasgow
Verified email at beatson.gla.ac.uk - Homepage
TitleCited byYear
Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress
ZT Schug, B Peck, DT Jones, Q Zhang, S Grosskurth, IS Alam, ...
Cancer cell 27 (1), 57-71, 2015
2742015
Copper compounds in anticancer strategies
S Tardito, L Marchio
Current medicinal chemistry 16 (11), 1325-1348, 2009
1662009
Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma
S Tardito, A Oudin, SU Ahmed, F Fack, O Keunen, L Zheng, H Miletic, ...
Nature cell biology 17 (12), 1556, 2015
1622015
Copper binding agents acting as copper ionophores lead to caspase inhibition and paraptotic cell death in human cancer cells
S Tardito, I Bassanetti, C Bignardi, L Elviri, M Tegoni, C Mucchino, ...
Journal of the American Chemical Society 133 (16), 6235-6242, 2011
1452011
Glucose and glutamine metabolism regulate human hematopoietic stem cell lineage specification
L Oburoglu, S Tardito, V Fritz, SC De Barros, P Merida, M Craveiro, ...
Cell stem cell 15 (2), 169-184, 2014
992014
The thioxotriazole copper (II) complex A0 induces endoplasmic reticulum stress and paraptotic death in human cancer cells
S Tardito, C Isella, E Medico, L Marchio, E Bevilacqua, M Hatzoglou, ...
Journal of Biological Chemistry 284 (36), 24306-24319, 2009
992009
Copper-dependent cytotoxicity of 8-hydroxyquinoline derivatives correlates with their hydrophobicity and does not require caspase activation
S Tardito, A Barilli, I Bassanetti, M Tegoni, O Bussolati, R Franchi-Gazzola, ...
Journal of medicinal chemistry 55 (23), 10448-10459, 2012
962012
Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells
EM Kuntz, P Baquero, AM Michie, K Dunn, S Tardito, TL Holyoake, ...
Nature medicine 23 (10), 1234, 2017
702017
Thioamido coordination in a thioxo-1, 2, 4-triazole copper (II) complex enhances nonapoptotic programmed cell death associated with copper accumulation and oxidative stress iná…
S Tardito, O Bussolati, M Maffini, M Tegoni, M Giannetto, V Dall'Asta, ...
Journal of medicinal chemistry 50 (8), 1916-1924, 2007
692007
HIF-independent role of prolyl hydroxylases in the cellular response to amino acids
RV Durßn, ED MacKenzie, H Boulahbel, C Frezza, L Heiserich, S Tardito, ...
Oncogene 32 (38), 4549, 2013
682013
Platelet gel in the treatment of cutaneous ulcers: the experience of the Immunohaematology and Transfusion Centre of Parma
G Bernuzzi, S Tardito, O Bussolati, D Adorni, S Cantarelli, F Fagnoni, ...
Blood Transfusion 8 (4), 237, 2010
542010
Non-apoptotic programmed cell death induced by a copper (II) complex in human fibrosarcoma cells
S Tardito, O Bussolati, F Gaccioli, R Gatti, S Guizzardi, J Uggeri, ...
Histochemistry and cell biology 126 (4), 473-482, 2006
502006
Expanding targets for a metabolic therapy of cancer: L-asparaginase
D Covini, S Tardito, O Bussolati, L R Chiarelli, M V Pasquetto, R Digilio, ...
Recent patents on anti-cancer drug discovery 7 (1), 4-13, 2012
472012
Polyphenon E«, a standardized green tea extract, induces endoplasmic reticulum stress, leading to death of immortalized PNT1a cells by anoikis and tumorigenic PC3 by necroptosis
F Rizzi, V Naponelli, A Silva, A Modernelli, I Ramazzina, M Bonacini, ...
Carcinogenesis 35 (4), 828-839, 2013
392013
L-Asparaginase and inhibitors of glutamine synthetase disclose glutamine addiction of β-catenin-mutated human hepatocellular carcinoma cells
S Tardito, M Chiu, J Uggeri, A Zerbini, F Da Ros, V Dall'Asta, G Missale, ...
Current cancer drug targets 11 (8), 929-943, 2011
352011
Cancer metabolism at a glance
A Vazquez, JJ Kamphorst, EK Markert, ZT Schug, S Tardito, E Gottlieb
J Cell Sci 129 (18), 3367-3373, 2016
342016
The inhibition of glutamine synthetase sensitizes human sarcoma cells to L-asparaginase
S Tardito, J Uggeri, C Bozzetti, MG Bianchi, BM Rotoli, R Franchi-Gazzola, ...
Cancer chemotherapy and pharmacology 60 (5), 751-758, 2007
342007
Glutamine stimulates mTORC1 independent of the cell content of essential amino acids
M Chiu, S Tardito, A Barilli, MG Bianchi, V Dall’Asta, O Bussolati
Amino acids 43 (6), 2561-2567, 2012
322012
Synthesis, solution equilibria and antiproliferative activity of copper (II) aminomethyltriazole and aminomethylthioxotriazoline complexes
F Gaccioli, R Franchi-Gazzola, M Lanfranchi, L Marchi˛, G Metta, ...
Journal of inorganic biochemistry 99 (8), 1573-1584, 2005
322005
Glutamine depletion by crisantaspase hinders the growth of human hepatocellular carcinoma xenografts
M Chiu, S Tardito, S Pillozzi, A Arcangeli, A Armento, J Uggeri, G Missale, ...
British journal of cancer 111 (6), 1159, 2014
232014
The system can't perform the operation now. Try again later.
Articles 1–20