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Fabien Garcon
Fabien Garcon
Verified email at babraham.ac.uk
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Cited by
Year
Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage
I Angulo, O Vadas, F Garçon, E Banham-Hall, V Plagnol, TR Leahy, ...
Science 342 (6160), 866-871, 2013
6242013
The p110δ isoform of phosphoinositide 3-kinase controls clonal expansion and differentiation of Th cells
K Okkenhaug, DT Patton, A Bilancio, F Garçon, WC Rowan, ...
The Journal of immunology 177 (8), 5122-5128, 2006
2482006
The PI3K isoforms p110α and p110δ are essential for pre–B cell receptor signaling and B cell development
F Ramadani, DJ Bolland, F Garcon, JL Emery, B Vanhaesebroeck, ...
Science signaling 3 (134), ra60-ra60, 2010
2442010
CD28 provides T-cell costimulation and enhances PI3K activity at the immune synapse independently of its capacity to interact with the p85/p110 heterodimer
F Garçon, DT Patton, JL Emery, E Hirsch, R Rottapel, T Sasaki, ...
Blood, The Journal of the American Society of Hematology 111 (3), 1464-1471, 2008
1732008
The loss of PTEN allows TCR αβ Lineage thymocytes to bypass IL-7 and pre-TCR–mediated signaling
TJ Hagenbeek, M Naspetti, F Malergue, F Garçon, JA Nunès, ...
The Journal of experimental medicine 200 (7), 883-894, 2004
1612004
p110γ and p110δ isoforms of phosphoinositide 3-kinase differentially regulate natural killer cell migration in health and disease
A Saudemont, F Garçon, H Yadi, M Roche-Molina, N Kim, ...
Proceedings of the National Academy of Sciences 106 (14), 5795-5800, 2009
1042009
Functional interaction of RasGAP-binding proteins Dok-1 and Dok-2 with the Tec protein tyrosine kinase
A Gerard, C Favre, F Garcon, JG Nemorin, P Duplay, S Pastor, Y Collette, ...
Oncogene 23 (8), 1594-1598, 2004
532004
Pten loss in CD4 T cells enhances their helper function but does not lead to autoimmunity or lymphoma
DR Soond, F Garçon, DT Patton, J Rolf, M Turner, C Scudamore, ...
The Journal of Immunology 188 (12), 5935-5943, 2012
432012
Pten loss in CD4 T cells enhances their helper function but does not lead to autoimmunity or lymphoma
DR Soond, F Garçon, DT Patton, J Rolf, M Turner, C Scudamore, ...
The Journal of Immunology 188 (12), 5935-5943, 2012
432012
The PI3K p110δ controls T-cell development, differentiation and regulation
DT Patton, F Garcon, K Okkenhaug
Biochemical Society Transactions 35 (2), 167-171, 2007
412007
The PI3K p110δ controls T-cell development, differentiation and regulation
DT Patton, F Garcon, K Okkenhaug
Biochemical Society Transactions 35 (2), 167-171, 2007
412007
Intravital imaging of adoptive T-cell morphology, mobility and trafficking following immune checkpoint inhibition in a mouse melanoma model
D Lau, F Garçon, A Chandra, LM Lechermann, L Aloj, ER Chilvers, ...
Frontiers in immunology 11, 1514, 2020
302020
The SH3 domain of Tec kinase is essential for its targeting to activated CD28 costimulatory molecule
F Garçon, M Ghiotto, A Gérard, WC Yang, D Olive, JA Nunès
European journal of immunology 34 (7), 1972-1980, 2004
292004
PI3Kδ promotes CD4+ T‐cell interactions with antigen‐presenting cells by increasing LFA‐1 binding to ICAM‐1
F Garçon, K Okkenhaug
Immunology and cell biology 94 (5), 486-495, 2016
272016
Tec kinase migrates to the T cell-APC interface independently of its pleckstrin homology domain
F Garçon, G Bismuth, D Isnardon, D Olive, JA Nunès
The Journal of Immunology 173 (2), 770-775, 2004
172004
A CRISPR screen targeting PI3K effectors identifies RASA3 as a negative regulator of LFA-1–mediated adhesion in T cells
KH Johansen, DP Golec, B Huang, C Park, JH Thomsen, S Preite, ...
Science signaling 15 (743), eabl9169, 2022
112022
Non-invasive multiphoton imaging of islets transplanted into the pinna of the NOD mouse ear reveals the immediate effect of anti-CD3 treatment in autoimmune diabetes
RA Benson, F Garcon, A Recino, JR Ferdinand, MR Clatworthy, ...
Frontiers in immunology 9, 318015, 2018
102018
Travel informations on the Tec kinases during lymphocyte activation
F Garçon, JA Nunès
Lymphocyte Signal Transduction, 15-27, 2006
22006
Differential roles for the Class IA PI3Ks p110alpha and p110delta in T cell activation
A MacQueen, F Garcon, A Amour, K Okkenhaug
IMMUNOLOGY 137, 14-14, 2012
2012
The p110g and p110d isoforms of phosphoinositide 3-kinase differentially regulate natural killer cell migration
A Saudemont, F Garcon, H Yadi, M Roche-Molina, A Segonds-Pichon, ...
Immunology 125, 81-81, 2008
2008
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