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Niamh M C Connolly
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Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases
NMC Connolly, P Theurey, V Adam-Vizi, NG Bazan, P Bernardi, ...
Cell Death & Differentiation, 1, 2017
1482017
Cerebrospinal fluid microRNAs are potential biomarkers of temporal lobe epilepsy and status epilepticus
R Raoof, EM Jimenez-Mateos, S Bauer, B Tackenberg, F Rosenow, ...
Scientific reports 7 (1), 3328, 2017
1132017
Dual-center, dual-platform microRNA profiling identifies potential plasma biomarkers of adult temporal lobe epilepsy
R Raoof, S Bauer, H El Naggar, NMC Connolly, GP Brennan, E Brindley, ...
EBioMedicine 38, 127-141, 2018
982018
Two-step activation of FOXO3 by AMPK generates a coherent feed-forward loop determining excitotoxic cell fate
D Davila, NMC Connolly, H Bonner, P Weisová, H Dussmann, ...
Cell Death & Differentiation 19 (10), 1677-1688, 2012
802012
Single-cell imaging of bioenergetic responses to neuronal excitotoxicity and oxygen and glucose deprivation
NMC Connolly, H Düssmann, U Anilkumar, HJ Huber, JHM Prehn
Journal of Neuroscience 34 (31), 10192-10205, 2014
672014
Systems biology identifies preserved integrity but impaired metabolism of mitochondria due to a glycolytic defect in Alzheimer's disease neurons
P Theurey, NMC Connolly, I Fortunati, E Basso, S Lauwen, C Ferrante, ...
Aging cell 18 (3), e12924, 2019
532019
miRNAmeConverter: an R/bioconductor package for translating mature miRNA names to different miRBase versions
SJ Haunsberger, NMC Connolly, JHM Prehn
Bioinformatics 33 (4), 592-593, 2017
522017
A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy
MT Venø, CR Reschke, G Morris, NMC Connolly, J Su, Y Yan, T Engel, ...
Proceedings of the National Academy of Sciences 117 (27), 15977-15988, 2020
502020
Genome-wide microRNA profiling of plasma from three different animal models identifies biomarkers of temporal lobe epilepsy
GP Brennan, S Bauer, T Engel, EM Jimenez-Mateos, F Del Gallo, ...
Neurobiology of Disease 144, 105048, 2020
452020
The metabolic response to excitotoxicity–lessons from single-cell imaging
NMC Connolly, JHM Prehn
Journal of bioenergetics and biomembranes 47 (1-2), 75-88, 2015
372015
Mechanisms and mathematical modeling of ROS production by the mitochondrial electron transport chain
S Chenna, WJH Koopman, JHM Prehn, NMC Connolly
American Journal of Physiology-Cell Physiology 323 (1), C69-C83, 2022
312022
Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling
L Naia, CM Pinho, G Dentoni, J Liu, NS Leal, DMS Ferreira, B Schreiner, ...
BMC biology 19, 1-21, 2021
282021
Altered biogenesis and microRNA content of hippocampal exosomes following experimental status epilepticus
A Batool, TDM Hill, NT Nguyen, E Langa, M Diviney, C Mooney, ...
Frontiers in neuroscience 13, 1404, 2020
242020
Systemic delivery of antagomirs during blood-brain barrier disruption is disease-modifying in experimental epilepsy
CR Reschke, LFA Silva, VR Vangoor, M Rosso, B David, BL Cavanagh, ...
Molecular Therapy 29 (6), 2041-2052, 2021
232021
AMPK Preferentially Depresses Retrograde Transport of Axonal Mitochondria during Localized Nutrient Deprivation
O Watters, NMC Connolly, HG König, H Düssmann, JHM Prehn
Journal of Neuroscience 40 (25), 4798-4812, 2020
212020
Electrical stimulation of the ventral hippocampal commissure delays experimental epilepsy and is associated with altered microRNA expression
LS Costard, V Neubert, MT Venø, J Su, J Kjems, NMC Connolly, ...
Brain Stimulation 12 (6), 1390-1401, 2019
182019
Defining external factors that determine neuronal survival, apoptosis and necrosis during excitotoxic injury using a high content screening imaging platform
U Anilkumar, P Weisova, J Schmid, T Bernas, HJ Huber, H Düssmann, ...
PloS one 12 (11), e0188343, 2017
152017
Computational Analysis of AMPK-Mediated Neuroprotection Suggests Acute Excitotoxic Bioenergetics and Glucose Dynamics Are Regulated by a Minimal Set of Critical Reactions
NMC Connolly, B D’Orsi, N Monsefi, HJ Huber, JHM Prehn
PloS one 11 (2), e0148326, 2016
142016
Targeting the apoptosis pathway to treat tumours of the paediatric nervous system
MC Fitzgerald, PJ O’Halloran, NMC Connolly, BM Murphy
Cell Death & Disease 13 (5), 460, 2022
112022
MicroRNA-335-5p suppresses voltage-gated sodium channel expression and may be a target for seizure control
M Heiland, NMC Connolly, O Mamad, NT Nguyen, JC Kesavan, E Langa, ...
Proceedings of the National Academy of Sciences 120 (30), e2216658120, 2023
102023
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Articles 1–20