David A. Tumbarello
David A. Tumbarello
Lecturer in Biomedical Sciences, Biological Sciences, University of Southampton
Verified email at - Homepage
Cited by
Cited by
Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome
DA Tumbarello, BJ Waxse, SD Arden, NA Bright, J Kendrick-Jones, ...
Nature Cell Biology 14 (10), 1024-1035, 2012
The autophagy receptor TAX1BP1 and the molecular motor myosin VI are required for clearance of salmonella typhimurium by autophagy
DA Tumbarello, PT Manna, M Allen, M Bycroft, SD Arden, ...
PLoS pathogens 11 (10), e1005174, 2015
Hic-5 promotes invadopodia formation and invasion during TGF-β–induced epithelial–mesenchymal transition
J Pignatelli, DA Tumbarello, RP Schmidt, CE Turner
The Journal of Cell Biology 197 (3), 421-437, 2012
The paxillin LD motifs
DA Tumbarello, MC Brown, CE Turner
FEBS letters 513 (1), 114-118, 2002
Myosin VI and its cargo adaptors–linking endocytosis and autophagy
DA Tumbarello, J Kendrick-Jones, F Buss
J Cell Sci 126 (12), 2561-2570, 2013
Hic‐5 contributes to epithelial‐mesenchymal transformation through a RhoA/ROCK‐dependent pathway
DA Tumbarello, CE Turner
Journal of cellular physiology 211 (3), 736-747, 2007
Small-molecule inhibitors of myosin proteins
LM Bond, DA Tumbarello, J Kendrick-Jones, F Buss
Future 5 (1), 41-52, 2013
Optineurin: a coordinator of membrane-associated cargo trafficking and autophagy
TA Ryan, DA Tumbarello
Frontiers in Immunology 9, 1024, 2018
Regulation of paxillin family members during epithelial-mesenchymal transformation: a putative role for paxillin δ
DA Tumbarello, MC Brown, SE Hetey, CE Turner
Journal of cell science 118 (20), 4849-4863, 2005
Paxillin is essential for PTP-PEST-dependent regulation of cell spreading and motility: a role for paxillin kinase linker
JS Jamieson, DA Tumbarello, M Hallé, MC Brown, ML Tremblay, ...
Journal of Cell Science 118 (24), 5835-5847, 2005
Hic-5 promotes the hypertrophic scar myofibroblast phenotype by regulating the TGF-β1 autocrine loop
G Dabiri, DA Tumbarello, CE Turner, L Van De Water
Journal of Investigative Dermatology 128 (10), 2518-2525, 2008
Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion
H Brandstaetter, C Kishi-Itakura, DA Tumbarello, DJ Manstein, F Buss
Autophagy 10 (12), 2310-2323, 2014
β3 integrin modulates transforming growth factor beta induced (TGFBI) function and paclitaxel response in ovarian cancer cells
DA Tumbarello, J Temple, JD Brenton
Molecular cancer 11 (1), 1-15, 2012
Impaired Cargo Clearance in the Retinal Pigment Epithelium (RPE) Underlies Irreversible Blinding Diseases
E Keeling, AJ Lotery, DA Tumbarello, J Ratnayaka
Cells 7 (2), 16, 2018
Tollip coordinates Parkin‐dependent trafficking of mitochondrial‐derived vesicles
TA Ryan, EO Phillips, CL Collier, A JB Robinson, D Routledge, RE Wood, ...
The EMBO journal 39 (11), e102539, 2020
MYO6 Regulates Spatial Organization of Signaling Endosomes Driving AKT Activation and Actin Dynamics
TA Masters, DA Tumbarello, MV Chibalina, F Buss
Cell Reports 19 (10), 2088-2101, 2017
TGF-β1 slows the growth of pathogenic myofibroblasts through a mechanism requiring the focal adhesion protein, Hic-5
G Dabiri, DA Tumbarello, CE Turner, L Van De Water
Journal of Investigative Dermatology 128 (2), 280-291, 2008
SPARC Regulates Transforming Growth Factor Beta Induced (TGFBI) Extracellular Matrix Deposition and Paclitaxel Response in Ovarian Cancer Cells
DA Tumbarello, MR Andrews, JD Brenton
PLOS ONE 11 (9), e0162698, 2016
Axonal localization of integrins in the CNS is neuronal type and age dependent
MR Andrews, S Soleman, M Cheah, DA Tumbarello, MRJ Mason, ...
Eneuro 3 (4), 2016
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
Autophagy 12 (1), 1-222, 2016
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