| Intrinsic and extrinsic mechanisms contribute to maintain the JAK/STAT pathway aberrantly activated in T-type large granular lymphocyte leukemia A Teramo, C Gattazzo, F Passeri, A Lico, G Tasca, A Cabrelle, V Martini, ... Blood, The Journal of the American Society of Hematology 121 (19), 3843-3854, 2013 | 118 | 2013 |
| Clofazimine, Psora-4 and PAP-1, inhibitors of the potassium channel Kv1. 3, as a new and selective therapeutic strategy in chronic lymphocytic leukemia L Leanza, L Trentin, KA Becker, F Frezzato, M Zoratti, G Semenzato, ... Leukemia 27 (8), 1782-1785, 2013 | 97 | 2013 |
| Lyn-mediated SHP-1 recruitment to CD5 contributes to resistance to apoptosis of B-cell chronic lymphocytic leukemia cells E Tibaldi, AM Brunati, F Zonta, F Frezzato, C Gattazzo, R Zambello, ... Leukemia 25 (11), 1768-1781, 2011 | 81 | 2011 |
| Geldanamycin-induced Lyn dissociation from aberrant Hsp90-stabilized cytosolic complex is an early event in apoptotic mechanisms in B-chronic lymphocytic leukemia L Trentin, M Frasson, A Donella-Deana, F Frezzato, MA Pagano, E Tibaldi, ... Blood, The Journal of the American Society of Hematology 112 (12), 4665-4674, 2008 | 76 | 2008 |
| Hexokinase 2 displacement from mitochondria‐associated membranes prompts Ca2+‐dependent death of cancer cells F Ciscato, R Filadi, I Masgras, M Pizzi, O Marin, N Damiano, P Pizzo, ... EMBO reports 21 (7), e49117, 2020 | 71 | 2020 |
| Telomere length and telomerase levels delineate subgroups of B-cell chronic lymphocytic leukemia with different biological characteristics and clinical outcomes E Rampazzo, L Bonaldi, L Trentin, C Visco, S Keppel, S Giunco, ... Haematologica 97 (1), 56, 2012 | 71 | 2012 |
| High-density lipoproteins downregulate CCL2 production in human fibroblast-like synoviocytes stimulated by urate crystals A Scanu, F Oliviero, L Gruaz, P Sfriso, A Pozzuoli, F Frezzato, C Agostini, ... Arthritis research & therapy 12, 1-10, 2010 | 63 | 2010 |
| S1P1 expression is controlled by the pro-oxidant activity of p66Shc and is impaired in B-CLL patients with unfavorable prognosis N Capitani, L Patrussi, L Trentin, OM Lucherini, E Cannizzaro, ... Blood, The Journal of the American Society of Hematology 120 (22), 4391-4399, 2012 | 59 | 2012 |
| Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A F Zonta, MA Pagano, L Trentin, E Tibaldi, F Frezzato, V Trimarco, M Facco, ... Blood, The Journal of the American Society of Hematology 125 (24), 3747-3755, 2015 | 54 | 2015 |
| Endogenous reactive oxygen species content and modulation of tyrosine phosphorylation during sperm capacitation G Dona, C Fiore, E Tibaldi, F Frezzato, A Andrisani, G Ambrosini, ... International journal of andrology 34 (5pt1), 411-419, 2011 | 54 | 2011 |
| Cross-talk between chronic lymphocytic leukemia (CLL) tumor B cells and mesenchymal stromal cells (MSCs): implications for neoplastic cell survival V Trimarco, E Ave, M Facco, G Chiodin, F Frezzato, V Martini, C Gattazzo, ... Oncotarget 6 (39), 42130, 2015 | 53 | 2015 |
| Enhanced chemokine receptor recycling and impaired S1P1 expression promote leukemic cell infiltration of lymph nodes in chronic lymphocytic leukemia L Patrussi, N Capitani, V Martini, M Pizzi, V Trimarco, F Frezzato, F Marino, ... Cancer research 75 (19), 4153-4163, 2015 | 52 | 2015 |
| In chronic lymphocytic leukemia the JAK2/STAT3 pathway is constitutively activated and its inhibition leads to CLL cell death unaffected by the protective bone marrow … F Severin, F Frezzato, A Visentin, V Martini, V Trimarco, S Carraro, ... Cancers 11 (12), 1939, 2019 | 47 | 2019 |
| Cortactin, another player in the Lyn signaling pathway, is over-expressed and alternatively spliced in leukemic cells from patients with B-cell chronic lymphocytic leukemia C Gattazzo, V Martini, F Frezzato, V Trimarco, E Tibaldi, M Castelli, ... haematologica 99 (6), 1069, 2014 | 46 | 2014 |
| HS1, a Lyn kinase substrate, is abnormally expressed in B-chronic lymphocytic leukemia and correlates with response to fludarabine-based regimen F Frezzato, C Gattazzo, V Martini, V Trimarco, A Teramo, S Carraro, ... PLoS One 7 (6), e39902, 2012 | 44 | 2012 |
| HSP70/HSF1 axis, regulated via a PI3K/AKT pathway, is a druggable target in chronic lymphocytic leukemia F Frezzato, F Raggi, V Martini, F Severin, V Trimarco, A Visentin, ... International journal of cancer 145 (11), 3089-3100, 2019 | 41 | 2019 |
| The combination of complex karyotype subtypes and IGHV mutational status identifies new prognostic and predictive groups in chronic lymphocytic leukaemia A Visentin, L Bonaldi, GM Rigolin, FR Mauro, A Martines, F Frezzato, ... British journal of cancer 121 (2), 150-156, 2019 | 40 | 2019 |
| The complex karyotype landscape in chronic lymphocytic leukemia allows the refinement of the risk of Richter syndrome transformation A Visentin, L Bonaldi, GM Rigolin, FR Mauro, A Martines, F Frezzato, ... Haematologica 107 (4), 868, 2022 | 39 | 2022 |
| Cortactin, a Lyn substrate, is a checkpoint molecule at the intersection of BCR and CXCR4 signalling pathway in chronic lymphocytic leukaemia cells V Martini, C Gattazzo, F Frezzato, V Trimarco, M Pizzi, G Chiodin, ... British journal of haematology 178 (1), 81-93, 2017 | 37 | 2017 |
| Integrated CLL scoring system, a new and simple index to predict time to treatment and overall survival in patients with chronic lymphocytic leukemia A Visentin, M Facco, F Frezzato, M Castelli, V Trimarco, V Martini, ... Clinical Lymphoma Myeloma and Leukemia 15 (10), 612-620. e5, 2015 | 36 | 2015 |
