|Clofazimine, Psora-4 and PAP-1, inhibitors of the potassium channel Kv1. 3, as a new and selective therapeutic strategy in chronic lymphocytic leukemia|
L Leanza, L Trentin, KA Becker, F Frezzato, M Zoratti, G Semenzato, ...
Leukemia 27 (8), 1782, 2013
|Geldanamycin-induced Lyn dissociation from aberrant Hsp90-stabilized cytosolic complex is an early event in apoptotic mechanisms in B-chronic lymphocytic leukemia|
L Trentin, M Frasson, A Donella-Deana, F Frezzato, MA Pagano, E Tibaldi, ...
Blood 112 (12), 4665-4674, 2008
|Lyn-mediated SHP-1 recruitment to CD5 contributes to resistance to apoptosis of B-cell chronic lymphocytic leukemia cells|
E Tibaldi, AM Brunati, F Zonta, F Frezzato, C Gattazzo, R Zambello, ...
Leukemia 25 (11), 1768, 2011
|Telomere length and telomerase levels delineate subgroups of B-cell chronic lymphocytic leukemia with different biological characteristics and clinical outcomes|
E Rampazzo, L Bonaldi, L Trentin, C Visco, S Keppel, S Giunco, ...
Haematologica 97 (1), 56-63, 2012
|Intrinsic and extrinsic mechanisms contribute to maintain the JAK/STAT pathway aberrantly activated in T-type large granular lymphocyte leukemia|
A Teramo, C Gattazzo, F Passeri, A Lico, G Tasca, A Cabrelle, V Martini, ...
Blood 121 (19), 3843-3854, 2013
|High-density lipoproteins downregulate CCL2 production in human fibroblast-like synoviocytes stimulated by urate crystals|
A Scanu, F Oliviero, L Gruaz, P Sfriso, A Pozzuoli, F Frezzato, C Agostini, ...
Arthritis research & therapy 12 (1), R23, 2010
|S1P1 expression is controlled by the pro-oxidant activity of p66Shc and is impaired in B-CLL patients with unfavorable prognosis|
N Capitani, L Patrussi, L Trentin, OM Lucherini, E Cannizzaro, ...
Blood 120 (22), 4391-4399, 2012
|Endogenous reactive oxygen species content and modulation of tyrosine phosphorylation during sperm capacitation|
G Dona, C Fiore, E Tibaldi, F Frezzato, A Andrisani, G Ambrosini, ...
International journal of andrology 34 (5pt1), 411-419, 2011
|HS1, a Lyn kinase substrate, is abnormally expressed in B-chronic lymphocytic leukemia and correlates with response to fludarabine-based regimen|
F Frezzato, C Gattazzo, V Martini, V Trimarco, A Teramo, S Carraro, ...
PLoS One 7 (6), e39902, 2012
|Integrated CLL scoring system, a new and simple index to predict time to treatment and overall survival in patients with chronic lymphocytic leukemia|
A Visentin, M Facco, F Frezzato, M Castelli, V Trimarco, V Martini, ...
Clinical Lymphoma Myeloma and Leukemia 15 (10), 612-620. e5, 2015
|Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A|
F Zonta, MA Pagano, L Trentin, E Tibaldi, F Frezzato, V Trimarco, M Facco, ...
Blood 125 (24), 3747-3755, 2015
|Lyn-mediated procaspase 8 dimerization blocks apoptotic signaling in B-cell chronic lymphocytic leukemia|
F Zonta, MA Pagano, L Trentin, E Tibaldi, F Frezzato, C Gattazzo, ...
Blood 123 (6), 875-883, 2014
|Enhanced chemokine receptor recycling and impaired S1P1 expression promote leukemic cell infiltration of lymph nodes in chronic lymphocytic leukemia|
L Patrussi, N Capitani, V Martini, M Pizzi, V Trimarco, F Frezzato, F Marino, ...
Cancer research 75 (19), 4153-4163, 2015
|Cortactin, another player in the Lyn signaling pathway, is over-expressed and alternatively spliced in leukemic cells from patients with B-cell chronic lymphocytic leukemia|
C Gattazzo, V Martini, F Frezzato, V Trimarco, E Tibaldi, M Castelli, ...
Haematologica 99 (6), 1069-1077, 2014
|Cross-talk between chronic lymphocytic leukemia (CLL) tumor B cells and mesenchymal stromal cells (MSCs): implications for neoplastic cell survival|
V Trimarco, E Ave, M Facco, G Chiodin, F Frezzato, V Martini, C Gattazzo, ...
Oncotarget 6 (39), 42130, 2015
|SERPINB3 expression on B-cell surface in autoimmune diseases and hepatitis C virus-related chronic liver infection|
L Vidalino, A Doria, SM Quarta, M Crescenzi, M Ruvoletto, F Frezzato, ...
Experimental Biology and Medicine 237 (7), 793-802, 2012
|Leukaemic cells from chronic lymphocytic leukaemia patients undergo apoptosis following microtubule depolymerization and L yn inhibition by nocodazole|
F Frezzato, V Trimarco, V Martini, C Gattazzo, E Ave, A Visentin, ...
British journal of haematology 165 (5), 659-672, 2014
|Apoptotic effect of cyclosporin a and dexamethasone in malignant cells of patients with B-chronic lymphocytic leukemia.|
A Cabrelle, N Maschio, S Carraro, F Frezzato, G Binotto, C Gattazzo, ...
Journal of biological regulators and homeostatic agents 23 (4), 239-250, 2009
|Cortactin, a Lyn substrate, is a checkpoint molecule at the intersection of BCR and CXCR4 signalling pathway in chronic lymphocytic leukaemia cells|
V Martini, C Gattazzo, F Frezzato, V Trimarco, M Pizzi, G Chiodin, ...
British journal of haematology 178 (1), 81-93, 2017
|Epidemiology and risk factors of invasive fungal infections in a large cohort of patients with chronic lymphocytic leukemia.|
A Visentin, C Gurrieri, S Imbergamo, F Lessi, SA Di Maggio, F Frezzato, ...
Hematological oncology 35 (4), 925, 2017