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ismail sergin
ismail sergin
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Year
Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation
S Epelman, KJ Lavine, AE Beaudin, DK Sojka, JA Carrero, B Calderon, ...
Immunity 40 (1), 91-104, 2014
14302014
Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis
I Sergin, TD Evans, X Zhang, S Bhattacharya, CJ Stokes, E Song, S Ali, ...
Nature communications 8 (1), 15750, 2017
2872017
Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelae
R Emanuel, I Sergin, S Bhattacharya, JN Turner, S Epelman, C Settembre, ...
Arteriosclerosis, thrombosis, and vascular biology 34 (9), 1942-1952, 2014
2272014
TFEB and trehalose drive the macrophage autophagy-lysosome system to protect against atherosclerosis
TD Evans, SJ Jeong, X Zhang, I Sergin, B Razani
Autophagy 14 (4), 724-726, 2018
1482018
Self-eating in the plaque: what macrophage autophagy reveals about atherosclerosis
I Sergin, B Razani
Trends in Endocrinology & Metabolism 25 (5), 225-234, 2014
1172014
Inclusion bodies enriched for p62 and polyubiquitinated proteins in macrophages protect against atherosclerosis
I Sergin, S Bhattacharya, R Emanuel, E Esen, CJ Stokes, TD Evans, B Arif, ...
Science signaling 9 (409), ra2-ra2, 2016
1032016
High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy
X Zhang, I Sergin, TD Evans, SJ Jeong, A Rodriguez-Velez, D Kapoor, ...
Nature metabolism 2 (1), 110-125, 2020
1012020
Location-dependent signaling of the group 1 metabotropic glutamate receptor mGlu5
YJI Jong, I Sergin, CA Purgert, KL O’Malley
Molecular pharmacology 86 (6), 774-785, 2014
682014
Target acquired: selective autophagy in cardiometabolic disease
TD Evans, I Sergin, X Zhang, B Razani
Science signaling 10 (468), eaag2298, 2017
642017
N-3 PUFAs induce inflammatory tolerance by formation of KEAP1-containing SQSTM1/p62-bodies and activation of NFE2L2
J Mildenberger, I Johansson, I Sergin, E Kjøbli, JK Damås, B Razani, ...
Autophagy 13 (10), 1664-1678, 2017
542017
Ursolic acid enhances macrophage autophagy and attenuates atherogenesis [S]
S Leng, S Iwanowycz, F Saaoud, J Wang, Y Wang, I Sergin, B Razani, ...
Journal of lipid research 57 (6), 1006-1016, 2016
492016
A clinically applicable gene-expression classifier reveals intrinsic and extrinsic contributions to consensus molecular subtypes in primary and metastatic colon cancer
R Piskol, L Huw, I Sergin, C Kljin, Z Modrusan, D Kim, N Kljavin, R Tam, ...
Clinical Cancer Research 25 (14), 4431-4442, 2019
462019
Sequences within the C terminus of the metabotropic glutamate receptor 5 (mGluR5) are responsible for inner nuclear membrane localization
I Sergin, YJI Jong, SK Harmon, V Kumar, KL O'Malley
Journal of Biological Chemistry 292 (9), 3637-3655, 2017
422017
Degradation and beyond: the macrophage lysosome as a nexus for nutrient sensing and processing in atherosclerosis
I Sergin, TD Evans, B Razani
Current opinion in lipidology 26 (5), 394-404, 2015
402015
Anti-angiogenic nanotherapy inhibits airway remodeling and hyper-responsiveness of dust mite triggered asthma in the Brown Norway rat
GM Lanza, J Jenkins, AH Schmieder, A Moldobaeva, G Cui, H Zhang, ...
Theranostics 7 (2), 377, 2017
312017
MAP4K4 negatively regulates CD8 T cell–mediated antitumor and antiviral immunity
E Esen, I Sergin, R Jesudason, P Himmels, JD Webster, H Zhang, M Xu, ...
Science immunology 5 (45), eaay2245, 2020
202020
Modulating oxysterol sensing to control macrophage apoptosis and atherosclerosis
TD Evans, I Sergin, X Zhang, B Razani
Circulation research 119 (12), 1258-1261, 2016
102016
Hypoxia in plaque macrophages: a new danger signal for interleukin-1β activation?
I Sergin, TD Evans, S Bhattacharya, B Razani
Circulation research 115 (10), 817-820, 2014
102014
Loss of Macrophage mTORC2 Drives Atherosclerosis via FoxO1 and IL-1β Signaling
X Zhang, TD Evans, S Chen, I Sergin, J Stitham, SJ Jeong, ...
Circulation research 133 (3), 200-219, 2023
42023
Alegato por el árbol
F Hallé
Libros del Jata, 2019
32019
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