| Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targets MC Baldauf, MF Orth, M Dallmayer, A Marchetto, JS Gerke, RA Rubio, ... Oncotarget 9 (2), 1587, 2018 | 83 | 2018 |
| PRC1: linking cytokinesis, chromosomal instability, and cancer evolution J Li, M Dallmayer, T Kirchner, J Musa, TGP Grünewald Trends in cancer 4 (1), 59-73, 2018 | 73 | 2018 |
| Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes J Musa, F Cidre-Aranaz, MM Aynaud, MF Orth, MML Knott, O Mirabeau, ... Nature communications 10 (1), 4128, 2019 | 58 | 2019 |
| Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma A Marchetto, S Ohmura, MF Orth, MML Knott, MV Colombo, C Arrigoni, ... Nature Communications 11 (1), 2423, 2020 | 40 | 2020 |
| Gene expression and immunohistochemical analyses identify SOX2 as major risk factor for overall survival and relapse in Ewing sarcoma patients G Sannino, A Marchetto, A Ranft, S Jabar, C Zacherl, R Alba-Rubio, ... EBioMedicine 47, 156-162, 2019 | 28 | 2019 |
| Translational evidence for RRM2 as a prognostic biomarker and therapeutic target in Ewing sarcoma S Ohmura, A Marchetto, MF Orth, J Li, S Jabar, A Ranft, E Vinca, ... Molecular Cancer 20, 1-7, 2021 | 27 | 2021 |
| Targeting the CALCB/RAMP1 axis inhibits growth of Ewing sarcoma M Dallmayer, J Li, S Ohmura, R Alba Rubio, MC Baldauf, TLB Hölting, ... Cell death & disease 10 (2), 116, 2019 | 26 | 2019 |
| High specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG positive Ewing sarcoma MF Orth, TLB Hölting, M Dallmayer, FS Wehweck, T Paul, J Musa, ... Cancers 12 (3), 644, 2020 | 22 | 2020 |
| Systematic identification of cancer-specific MHC-binding peptides with RAVEN MC Baldauf, JS Gerke, A Kirschner, F Blaeschke, M Effenberger, ... Oncoimmunology 7 (9), e1481558, 2018 | 22 | 2018 |
| Hepatitis B virus large surface protein is priming for hepatocellular carcinoma development via induction of cytokinesis failure J Musa, J Li, TGP Grünewald The Journal of pathology 247 (1), 6-8, 2019 | 20 | 2019 |
| Integrative clinical transcriptome analysis reveals TMPRSS2‐ERG dependency of prognostic biomarkers in prostate adenocarcinoma JS Gerke, MF Orth, Y Tolkach, L Romero‐Pérez, FS Wehweck, S Stein, ... International journal of cancer 146 (7), 2036-2046, 2020 | 12 | 2020 |
| Functional genomics identifies AMPD2 as a new prognostic marker for undifferentiated pleomorphic sarcoma MF Orth, JS Gerke, T Knösel, A Altendorf‐Hofmann, J Musa, ... International journal of cancer 144 (4), 859-867, 2019 | 12 | 2019 |
| Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer J Li, S Ohmura, A Marchetto, MF Orth, R Imle, M Dallmayer, J Musa, ... Nature Communications 12 (1), 5356, 2021 | 10 | 2021 |
| Integrative gene network and functional analyses identify a prognostically relevant key regulator of metastasis in Ewing sarcoma F Cidre-Aranaz, J Li, TLB Hölting, MF Orth, R Imle, S Kutschmann, ... Molecular Cancer 21 (1), 1-7, 2022 | 3 | 2022 |
| Neomorphic DNA-binding enables tumor-specific therapeutic gene expression in fusion-addicted childhood sarcoma TLB Hölting, F Cidre-Aranaz, D Matzek, B Popper, SJ Jacobi, CM Funk, ... Molecular Cancer 21 (1), 199, 2022 | 2 | 2022 |
| Chromosome 8 gain drives poor patient outcome via expression of 4E-BP1 in Ewing sarcoma CM Funk, MF Orth, K Aljakouch, A Ehlers, J Li, TLB Hoelting, R Will, ... bioRxiv, 2022.12. 11.519935, 2022 | | 2022 |
| PO-047 SOX6 is a direct EWSR1-FLI1 target gene contributing to tumour growth of ewing sarcoma A Marchetto, S Ohmura, M Orth, J Li, JS Gerke, F Wehweck, FC Aranaz, ... ESMO Open 3, A38-A39, 2018 | | 2018 |
| Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targets O Ozen, MC Baldauf, MF Orth, M Dallmayer, A Marchetto, JS Gerke, ... | | 2018 |
