Insulin‐like growth factor‐I gene therapy increases hippocampal neurogenesis, astrocyte branching and improves spatial memory in female aging rats J Pardo, M Uriarte, GM Cónsole, PC Reggiani, TF Outeiro, GR Morel, ... European Journal of Neuroscience 44 (4), 2120-2128, 2016 | 85 | 2016 |
Cognitive impairment and morphological changes in the dorsal hippocampus of very old female rats GR Morel, T Andersen, J Pardo, GO Zuccolilli, VL Cambiaggi, CB Hereñú, ... Neuroscience 303, 189-199, 2015 | 66 | 2015 |
The thymus–neuroendocrine axis: physiology, molecular biology, and therapeutic potential of the thymic peptide thymulin PC Reggiani, GR Morel, GM Cónsole, CG Barbeito, SS Rodriguez, ... Annals of the New York Academy of Sciences 1153 (1), 98-106, 2009 | 60 | 2009 |
Restorative effect of intracerebroventricular insulin-like growth factor-I gene therapy on motor performance in aging rats F Nishida, GR Morel, CB Hereñú, JI Schwerdt, RG Goya, EL Portiansky Neuroscience 177, 195-206, 2011 | 55 | 2011 |
Intracerebroventricular streptozotocin induces impaired Barnes maze spatial memory and reduces astrocyte branching in the CA1 and CA3 hippocampal regions MF Zappa Villar, J López Hanotte, E Falomir Lockhart, LS Trípodi, ... Journal of Neural Transmission 125, 1787-1803, 2018 | 45 | 2018 |
Therapeutic potential of IGF-I on hippocampal neurogenesis and function during aging GR Morel, ML León, M Uriarte, PC Reggiani, RG Goya Neurogenesis 4 (1), e1259709, 2017 | 41 | 2017 |
Estrogen inhibits tuberoinfundibular dopaminergic neurons but does not cause irreversible damage GR Morel, RW Carón, GM Cónsole, M Soaje, YE Sosa, SS Rodríguez, ... Brain research bulletin 80 (6), 347-352, 2009 | 39 | 2009 |
The ependymal route for insulin-like growth factor-1 gene therapy in the brain CB Hereñú, WE Sonntag, GR Morel, EL Portiansky, RG Goya Neuroscience 163 (1), 442-447, 2009 | 36 | 2009 |
Role of copper and cholesterol association in the neurodegenerative process N Arnal, GR Morel, MJT de Alaniz, O Castillo, CA Marra International journal of Alzheimer’s disease 2013, 2013 | 32 | 2013 |
Mesenchymal stem cells therapy improved the streptozotocin-induced behavioral and hippocampal impairment in rats MF Zappa Villar, J López Hanotte, J Pardo, GR Morel, G Mazzolini, ... Molecular neurobiology 57, 600-615, 2020 | 26 | 2020 |
Identification of a conserved gene signature associated with an exacerbated inflammatory environment in the hippocampus of aging rats J Pardo, MC Abba, E Lacunza, L Francelle, GR Morel, TF Outeiro, ... Hippocampus 27 (4), 435-449, 2017 | 25 | 2017 |
IGF-I gene therapy in aging rats modulates hippocampal genes relevant to memory function J Pardo, MC Abba, E Lacunza, OM Ogundele, I Paiva, GR Morel, ... The Journals of Gerontology: Series A 73 (4), 459-467, 2018 | 21 | 2018 |
Gene therapy and cell reprogramming for the aging brain: achievements and promise J Pardo, G R Morel, M Astiz, J I Schwerdt, M L Leon, S S Rodriguez, ... Current gene therapy 14 (1), 24-34, 2014 | 19 | 2014 |
Peripheral and mesencephalic transfer of a synthetic gene for the thymic peptide thymulin GR Morel, OA Brown, PC Reggiani, CB Hereñú, EL Portiansky, ... Brain research bulletin 69 (6), 647-651, 2006 | 19 | 2006 |
Umbilical cord cell therapy improves spatial memory in aging rats M Lehmann, MF Zappa-Villar, MG García, G Mazzolini, M Canatelli-Mallat, ... Stem cell reviews and reports 15, 612-617, 2019 | 14 | 2019 |
Regulatable adenovector harboring the GFP and Yamanaka genes for implementing regenerative medicine in the brain M Lehmann, M Canatelli-Mallat, P Chiavellini, GR Morel, PC Reggiani, ... Gene therapy 26 (10), 432-440, 2019 | 13 | 2019 |
Glial cell line-derived neurotrophic factor gene therapy ameliorates chronic hyperprolactinemia in senile rats GR Morel, YE Sosa, MJ Bellini, NG Carri, SS Rodriguez, MC Bohn, ... Neuroscience 167 (3), 946-953, 2010 | 11 | 2010 |
Insulin-like growth factor-I gene therapy reverses morphologic changes and reduces hyperprolactinemia in experimental rat prolactinomas GM Console, CB Herenu, GA Camihort, GC Luna, MI Bracamonte, ... Molecular Cancer 7, 1-7, 2008 | 11 | 2008 |
Hippocampal DNA methylation, epigenetic age, and spatial memory performance in young and old rats P Chiavellini, M Lehmann, M Canatelli Mallat, JA Zoller, CB Herenu, ... The Journals of Gerontology: Series A 77 (12), 2387-2394, 2022 | 10 | 2022 |
Mesenchymal stem cell therapy improves spatial memory and hippocampal structure in aging rats MFZ Villar, M Lehmann, MG García, G Mazzolini, GR Morel, GM Cónsole, ... Behavioural Brain Research 374, 111887, 2019 | 9 | 2019 |