| Melanopsin cells are the principal conduits for rod–cone input to non-image-forming vision AD Güler, JL Ecker, GS Lall, S Haq, CM Altimus, HW Liao, AR Barnard, ... Nature 453 (7191), 102-105, 2008 | 959 | 2008 |
| Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial RE MacLaren, M Groppe, AR Barnard, CL Cottriall, T Tolmachova, ... The Lancet 383 (9923), 1129-1137, 2014 | 875 | 2014 |
| The after-hours mutant reveals a role for Fbxl3 in determining mammalian circadian period SIH Godinho, ES Maywood, L Shaw, V Tucci, AR Barnard, L Busino, ... Science 316 (5826), 897-900, 2007 | 527 | 2007 |
| Reversal of end-stage retinal degeneration and restoration of visual function by photoreceptor transplantation MS Singh, P Charbel Issa, R Butler, C Martin, DM Lipinski, S Sekaran, ... Proceedings of the National Academy of Sciences 110 (3), 1101-1106, 2013 | 296 | 2013 |
| When clocks go bad: neurobehavioural consequences of disrupted circadian timing AR Barnard, PM Nolan PLoS genetics 4 (5), e1000040, 2008 | 243 | 2008 |
| Initial results from a first-in-human gene therapy trial on X-linked retinitis pigmentosa caused by mutations in RPGR J Cehajic-Kapetanovic, K Xue, C Martinez-Fernandez de la Camara, ... Nature medicine 26 (3), 354-359, 2020 | 242 | 2020 |
| Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion MS Singh, J Balmer, AR Barnard, SA Aslam, D Moralli, CM Green, ... Nature communications 7 (1), 13537, 2016 | 234 | 2016 |
| Visual acuity after retinal gene therapy for choroideremia TL Edwards, JK Jolly, M Groppe, AR Barnard, CL Cottriall, T Tolmachova, ... New England Journal of Medicine 374 (20), 1996-1998, 2016 | 223 | 2016 |
| Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia K Xue, JK Jolly, AR Barnard, A Rudenko, AP Salvetti, MI Patrício, ... Nature medicine 24 (10), 1507-1512, 2018 | 175 | 2018 |
| Melanopsin regulates visual processing in the mouse retina AR Barnard, S Hattar, MW Hankins, RJ Lucas Current biology 16 (4), 389-395, 2006 | 174 | 2006 |
| Function of human pluripotent stem cell-derived photoreceptor progenitors in blind mice AO Barnea-Cramer, W Wang, SJ Lu, MS Singh, C Luo, H Huo, ... Scientific reports 6 (1), 29784, 2016 | 159 | 2016 |
| Rescue of the Stargardt phenotype in Abca4 knockout mice through inhibition of vitamin A dimerization P Charbel Issa, AR Barnard, P Herrmann, I Washington, RE MacLaren Proceedings of the National Academy of Sciences 112 (27), 8415-8420, 2015 | 126 | 2015 |
| Fundus autofluorescence in the Abca4−/− mouse model of Stargardt disease—correlation with accumulation of A2E, retinal function, and histology PC Issa, AR Barnard, MS Singh, E Carter, Z Jiang, RA Radu, ... Investigative ophthalmology & visual science 54 (8), 5602-5612, 2013 | 121 | 2013 |
| Codon-optimized RPGR improves stability and efficacy of AAV8 gene therapy in two mouse models of X-linked retinitis pigmentosa MD Fischer, ME McClements, CMF de la Camara, JS Bellingrath, ... Molecular Therapy 25 (8), 1854-1865, 2017 | 118 | 2017 |
| Functional expression of Rab escort protein 1 following AAV2-mediated gene delivery in the retina of choroideremia mice and human cells ex vivo T Tolmachova, OE Tolmachov, AR Barnard, SR de Silva, DM Lipinski, ... Journal of molecular medicine 91, 825-837, 2013 | 97 | 2013 |
| Novel gene function revealed by mouse mutagenesis screens for models of age-related disease PK Potter, MR Bowl, P Jeyarajan, L Wisby, A Blease, ME Goldsworthy, ... Nature communications 7 (1), 12444, 2016 | 95 | 2016 |
| Retinal pigment epithelium defects accelerate photoreceptor degeneration in cell type–specific knockout mouse models of choroideremia T Tolmachova, ST Wavre-Shapton, AR Barnard, RE MacLaren, CE Futter, ... Investigative ophthalmology & visual science 51 (10), 4913-4920, 2010 | 94 | 2010 |
| CNTF gene therapy confers lifelong neuroprotection in a mouse model of human retinitis pigmentosa DM Lipinski, AR Barnard, MS Singh, C Martin, EJ Lee, WIL Davies, ... Molecular Therapy 23 (8), 1308-1319, 2015 | 88 | 2015 |
| Long-term restoration of visual function in end-stage retinal degeneration using subretinal human melanopsin gene therapy SR De Silva, AR Barnard, S Hughes, SKE Tam, C Martin, MS Singh, ... Proceedings of the National Academy of Sciences 114 (42), 11211-11216, 2017 | 83 | 2017 |
| The regulatory factor ZFHX3 modifies circadian function in SCN via an AT motif-driven axis MJ Parsons, M Brancaccio, S Sethi, ES Maywood, R Satija, JK Edwards, ... Cell 162 (3), 607-621, 2015 | 83 | 2015 |
