Martin Reijns
Martin Reijns
Senior Postdoctoral Researcher, University of Edinburgh
Verified email at igmm.ed.ac.uk
Title
Cited by
Cited by
Year
cGAS surveillance of micronuclei links genome instability to innate immunity
KJ Mackenzie, P Carroll, CA Martin, O Murina, A Fluteau, DJ Simpson, ...
Nature 548 (7668), 461-465, 2017
3872017
Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development
MAM Reijns, B Rabe, RE Rigby, P Mill, KR Astell, LA Lettice, S Boyle, ...
Cell 149 (5), 1008-1022, 2012
3332012
A role for Q/N-rich aggregation-prone regions in P-body localization
MAM Reijns, RD Alexander, MP Spiller, JD Beggs
Journal of cell science 121 (15), 2463-2472, 2008
2222008
Identification of VP19 and VP15 of white spot syndrome virus (WSSV) and glycosylation status of the WSSV major structural proteins
MCW van Hulten, M Reijns, AMG Vermeesch, F Zandbergen, JM Vlak
Journal of general virology 83 (1), 257-265, 2002
1642002
Lagging-strand replication shapes the mutational landscape of the genome
MAM Reijns, H Kemp, J Ding, SM de Procé, AP Jackson, MS Taylor
Nature 518 (7540), 502-506, 2015
1482015
Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair
MM Ghodgaonkar, F Lazzaro, M Olivera-Pimentel, M Artola-Borán, ...
Molecular cell 50 (3), 323-332, 2013
1452013
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity
C Günther, B Kind, MAM Reijns, N Berndt, M Martinez-Bueno, C Wolf, ...
The Journal of clinical investigation 125 (1), 413-424, 2015
1202015
Human and mouse mutations in WDR35 cause short-rib polydactyly syndromes due to abnormal ciliogenesis
P Mill, PJ Lockhart, E Fitzpatrick, HS Mountford, EA Hall, MAM Reijns, ...
The American Journal of Human Genetics 88 (4), 508-515, 2011
1182011
Ribonuclease H2 mutations induce a cGAS/STING‐dependent innate immune response
KJ Mackenzie, P Carroll, L Lettice, Ž Tarnauskaitė, K Reddy, F Dix, ...
The EMBO journal 35 (8), 831-844, 2016
1152016
RNA: DNA hybrids are a novel molecular pattern sensed by TLR9
RE Rigby, LM Webb, KJ Mackenzie, Y Li, A Leitch, MAM Reijns, ...
The EMBO journal 33 (6), 542-558, 2014
1142014
PCNA directs type 2 RNase H activity on DNA replication and repair substrates
D Bubeck, MAM Reijns, SC Graham, KR Astell, EY Jones, AP Jackson
Nucleic acids research 39 (9), 3652-3666, 2011
1112011
CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions
M Zimmermann, O Murina, MAM Reijns, A Agathanggelou, R Challis, ...
Nature 559 (7713), 285-289, 2018
962018
The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease
MAM Reijns, D Bubeck, LCD Gibson, SC Graham, GS Baillie, EY Jones, ...
Journal of Biological Chemistry 286 (12), 10530-10539, 2011
682011
TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism
ME Harley, O Murina, A Leitch, MR Higgs, LS Bicknell, G Yigit, ...
Nature genetics 48 (1), 36-43, 2016
512016
Mutagenesis of PepA suggests a new model for the Xer/cer synaptic complex
M Reijns, Y Lu, S Leach, SD Colloms
Molecular microbiology 57 (4), 927-941, 2005
442005
The Lsm2-8 complex determines nuclear localization of the spliceosomal U6 snRNA
MP Spiller, KL Boon, MAM Reijns, JD Beggs
Nucleic acids research 35 (3), 923-929, 2007
412007
Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism
JJ Reynolds, LS Bicknell, P Carroll, MR Higgs, R Shaheen, JE Murray, ...
Nature Genetics 49 (4), 537-549, 2017
392017
Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions
P Heyn, CV Logan, A Fluteau, RC Challis, T Auchynnikava, CA Martin, ...
Nature genetics 51 (1), 96-105, 2019
312019
Ribonuclease H2 in health and disease.
MA Reijns, AP Jackson
Biochemical Society transactions 42 (4), 717-725, 2014
312014
Requirements for nuclear localization of the Lsm2-8p complex and competition between nuclear and cytoplasmic Lsm complexes
MP Spiller, MAM Reijns, JD Beggs
Journal of cell science 120 (24), 4310-4320, 2007
262007
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