Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13146* | 2021 |
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase RC Russell, Y Tian, H Yuan, HW Park, YY Chang, J Kim, H Kim, ... Nature cell biology 15 (7), 741-750, 2013 | 1702 | 2013 |
Amino acid signalling upstream of mTOR JL Jewell, RC Russell, KL Guan Nature reviews Molecular cell biology 14 (3), 133-139, 2013 | 952 | 2013 |
Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy J Kim, YC Kim, C Fang, RC Russell, JH Kim, W Fan, R Liu, Q Zhong, ... Cell 152 (1), 290-303, 2013 | 851 | 2013 |
Autophagy regulation by nutrient signaling RC Russell, HX Yuan, KL Guan Cell research 24 (1), 42-57, 2014 | 761 | 2014 |
Differential regulation of mTORC1 by leucine and glutamine JL Jewell, YC Kim, RC Russell, FX Yu, HW Park, SW Plouffe, ... Science 347 (6218), 194-198, 2015 | 718 | 2015 |
YAP mediates crosstalk between the Hippo and PI (3) K–TOR pathways by suppressing PTEN via miR-29 K Tumaneng, K Schlegelmilch, RC Russell, D Yimlamai, H Basnet, ... Nature cell biology 14 (12), 1322-1329, 2012 | 492 | 2012 |
Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia CM Niemeyer, MW Kang, DH Shin, I Furlan, M Erlacher, NJ Bunin, ... Nature genetics 42 (9), 794-800, 2010 | 397 | 2010 |
VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail AJ Evans, RC Russell, O Roche, TN Burry, JE Fish, VWK Chow, WY Kim, ... Molecular and cellular biology 27 (1), 157-169, 2007 | 330 | 2007 |
Regulation of PIK3C3/VPS34 complexes by MTOR in nutrient stress-induced autophagy HX Yuan, RC Russell, KL Guan Autophagy 9 (12), 1983-1995, 2013 | 305 | 2013 |
Atg5 disassociates the V1V0-ATPase to promote exosome production and tumor metastasis independent of canonical macroautophagy H Guo, M Chitiprolu, L Roncevic, C Javalet, FJ Hemming, MT Trung, ... Developmental cell 43 (6), 716-730. e7, 2017 | 248 | 2017 |
Organ size control by Hippo and TOR pathways K Tumaneng, RC Russell, KL Guan Current Biology 22 (9), R368-R379, 2012 | 216 | 2012 |
An emerging role for TOR signaling in mammalian tissue and stem cell physiology RC Russell, C Fang, KL Guan Development 138 (16), 3343-3356, 2011 | 161 | 2011 |
Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease I Nemazanyy, B Blaauw, C Paolini, C Caillaud, F Protasi, A Mueller, ... EMBO molecular medicine 5 (6), 870-890, 2013 | 113 | 2013 |
Rag GTPases are cardioprotective by regulating lysosomal function YC Kim, HW Park, S Sciarretta, JS Mo, JL Jewell, RC Russell, X Wu, ... Nature communications 5 (1), 4241, 2014 | 91 | 2014 |
Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia RC Russell, RI Sufan, B Zhou, P Heir, S Bunda, SS Sybingco, SN Greer, ... Nature medicine 17 (7), 845-853, 2011 | 86 | 2011 |
The multifaceted role of autophagy in cancer RC Russell, KL Guan The EMBO journal 41 (13), e110031, 2022 | 80 | 2022 |
mGluR5 antagonism increases autophagy and prevents disease progression in the zQ175 mouse model of Huntington’s disease KS Abd-Elrahman, A Hamilton, SR Hutchinson, F Liu, RC Russell, ... Science signaling 10 (510), eaan6387, 2017 | 80 | 2017 |
NEDD8 acts as a ‘molecular switch’defining the functional selectivity of VHL RC Russell, M Ohh EMBO reports 9 (5), 486-491, 2008 | 78 | 2008 |
Iron overload inhibits late stage autophagic flux leading to insulin resistance JWS Jahng, RM Alsaadi, R Palanivel, E Song, VEB Hipolito, HK Sung, ... EMBO reports 20 (10), e47911, 2019 | 75 | 2019 |