| Structure elucidation of colibactin and its DNA cross-links M Xue, CS Kim, AR Healy, KM Wernke, Z Wang, MC Frischling, EE Shine, ... Science 365 (6457), eaax2685, 2019 | 182 | 2019 |
| A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage MJGW Ladds, IMM Van Leeuwen, CJ Drummond, S Chu, AR Healy, ... Nature communications 9 (1), 1107, 2018 | 86 | 2018 |
| A mechanistic model for colibactin-induced genotoxicity AR Healy, H Nikolayevskiy, JR Patel, JM Crawford, SB Herzon Journal of the American Chemical Society 138 (48), 15563-15570, 2016 | 80 | 2016 |
| Synthesis and structure–activity analysis of new phosphonium salts with potent activity against African trypanosomes A Taladriz, A Healy, EJ Flores Perez, V Herrero Garcia, C Rios Martinez, ... Journal of Medicinal Chemistry 55 (6), 2606-2622, 2012 | 64 | 2012 |
| ClbS is a cyclopropane hydrolase that confers colibactin resistance P Tripathi, EE Shine, AR Healy, CS Kim, SB Herzon, SD Bruner, ... Journal of the American Chemical Society 139 (49), 17719-17722, 2017 | 62 | 2017 |
| Convergent and modular synthesis of candidate precolibactins. Structural revision of precolibactin A AR Healy, MI Vizcaino, JM Crawford, SB Herzon Journal of the American Chemical Society 138 (16), 5426-5432, 2016 | 54 | 2016 |
| Domain-targeted metabolomics delineates the heterocycle assembly steps of colibactin biosynthesis EP Trautman, AR Healy, EE Shine, SB Herzon, JM Crawford Journal of the American Chemical Society 139 (11), 4195-4201, 2017 | 52 | 2017 |
| Molecular basis of gut microbiome-associated colorectal cancer: A synthetic perspective. AR Healy, SB Herzon Journal of the American Chemical Society, 2017 | 45 | 2017 |
| Structure and functional analysis of ClbQ, an unusual intermediate-releasing thioesterase from the colibactin biosynthetic pathway NS Guntaka, AR Healy, JM Crawford, SB Herzon, SD Bruner ACS chemical biology 12 (10), 2598-2608, 2017 | 42 | 2017 |
| Synthesis and reactivity of precolibactin 886 AR Healy, KM Wernke, CS Kim, NR Lees, JM Crawford, SB Herzon Nature chemistry 11 (10), 890-898, 2019 | 33 | 2019 |
| Total synthesis and biological evaluation of the tetramic acid based natural product harzianic acid and its stereoisomers AR Healy, F Vinale, M Lorito, NJ Westwood Organic letters 17 (3), 692-695, 2015 | 27 | 2015 |
| Model colibactins exhibit human cell genotoxicity in the absence of host bacteria EE Shine, M Xue, JR Patel, AR Healy, YV Surovtseva, SB Herzon, ... ACS chemical biology 13 (12), 3286-3293, 2018 | 24 | 2018 |
| Stereochemical Assignment of the Protein–Protein Interaction Inhibitor JBIR‐22 by Total Synthesis AR Healy, M Izumikawa, AMZ Slawin, K Shin‐ya, NJ Westwood Angewandte Chemie 127 (13), 4118-4122, 2015 | 24 | 2015 |
| Selective and Efficient Generation of ortho-Brominated para-Substituted Phenols in ACS-Grade Methanol D Georgiev, BWH Saes, HJ Johnston, SK Boys, A Healy, AN Hulme Molecules 21 (1), 88, 2016 | 16 | 2016 |
| Discovery of a novel ligand that modulates the protein–protein interactions of the AAA+ superfamily oncoprotein reptin AR Healy, DR Houston, L Remnant, AS Huart, V Brychtova, MM Maslon, ... Chemical Science 6 (5), 3109-3116, 2015 | 15 | 2015 |
| Synthetic studies on the bioactive tetramic acid JBIR-22 using a late stage Diels–Alder reaction AR Healy, NJ Westwood Organic & Biomolecular Chemistry 13 (42), 10527-10531, 2015 | 14 | 2015 |
| Sulfonyl chlorides as thiol surrogates for carbon–sulfur bond formation: One-pot synthesis of thioethers and thioesters T Cellnik, AR Healy The Journal of Organic Chemistry 87 (9), 6454-6458, 2022 | 13 | 2022 |
| Structure elucidation of colibactin and its DNA cross-links. Science 365: eaax2685 M Xue, CS Kim, AR Healy, KM Wernke, Z Wang, MC Frischling, EE Shine, ... | 8 | 2019 |
| A catalytic enantioselective stereodivergent aldol reaction MA Rahman, T Cellnik, BB Ahuja, L Li, AR Healy Science Advances 9 (11), eadg8776, 2023 | 6 | 2023 |
| Structure elucidation of secondary metabolites: Current frontiers and lingering pitfalls M DiBello, AR Healy, H Nikolayevskiy, Z Xu, SB Herzon Accounts of chemical research 56 (12), 1656-1668, 2023 | 5 | 2023 |
