| Plant UVR8 photoreceptor senses UV-B by tryptophan-mediated disruption of cross-dimer salt bridges JM Christie, AS Arvai, KJ Baxter, M Heilmann, AJ Pratt, A O’Hara, ... Science 335 (6075), 1492-1496, 2012 | 596 | 2012 |
| Protein structure determination in living cells by in-cell NMR spectroscopy D Sakakibara, A Sasaki, T Ikeya, J Hamatsu, T Hanashima, M Mishima, ... Nature 458 (7234), 102-105, 2009 | 446 | 2009 |
| The structure of mouse HP1 suggests a unique mode of single peptide recognition by the shadow chromo domain dimer SV Brasher, BO Smith, RH Fogh, D Nietlispach, A Thiru, PR Nielsen, ... The EMBO journal 19 (7), 1587-1597, 2000 | 388 | 2000 |
| Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d DH Brotherton, V Dhanaraj, S Wick, L Brizuela, PJ Domaille, E Volyanik, ... Nature 395 (6699), 244-250, 1998 | 288 | 1998 |
| The solution structure of the domain from MeCP2 that binds to methylated DNA RID Wakefield, BO Smith, X Nan, A Free, A Soteriou, D Uhrin, AP Bird, ... Journal of molecular biology 291 (5), 1055-1065, 1999 | 257 | 1999 |
| C-terminal region of the UV-B photoreceptor UVR8 initiates signaling through interaction with the COP1 protein C Cloix, E Kaiserli, M Heilmann, KJ Baxter, BA Brown, A O’Hara, ... Proceedings of the National Academy of Sciences 109 (40), 16366-16370, 2012 | 210 | 2012 |
| EPAC proteins transduce diverse cellular actions of cAMP G Borland, BO Smith, SJ Yarwood British journal of pharmacology 158 (1), 70-86, 2009 | 196 | 2009 |
| Activation of a primed RING E3-E2–ubiquitin complex by non-covalent ubiquitin L Buetow, M Gabrielsen, NG Anthony, H Dou, A Patel, H Aitkenhead, ... Molecular cell 58 (2), 297-310, 2015 | 145 | 2015 |
| Structure of the C3b binding site of CR1 (CD35), the immune adherence receptor BO Smith, RL Mallin, M Krych-Goldberg, X Wang, RE Hauhart, K Bromek, ... Cell 108 (6), 769-780, 2002 | 133 | 2002 |
| Polyoxometalate Clusters Integrated into Peptide Chains and as Inorganic Amino Acids: Solution‐and Solid‐Phase Approaches C Yvon, AJ Surman, M Hutin, J Alex, BO Smith, DL Long, L Cronin Angewandte Chemie 126 (13), 3404-3409, 2014 | 128 | 2014 |
| Structure of the cyclin-dependent kinase inhibitor p19Ink4d FY Luh, SJ Archer, PJ Domaille, BO Smith, D Owen, DH Brotherton, ... Nature 389 (6654), 999-1003, 1997 | 126 | 1997 |
| DNA recognition by the methyl-CpG binding domain of MeCP2 A Free, RID Wakefield, BO Smith, DTF Dryden, PN Barlow, AP Bird Journal of Biological Chemistry 276 (5), 3353-3360, 2001 | 117 | 2001 |
| High-resolution heteronuclear multidimensional NMR of proteins in living insect cells using a baculovirus protein expression system J Hamatsu, D O’Donovan, T Tanaka, T Shirai, Y Hourai, T Mikawa, T Ikeya, ... Journal of the American Chemical Society 135 (5), 1688-1691, 2013 | 114 | 2013 |
| Identification of bacterial target proteins for the salicylidene acylhydrazide class of virulence-blocking compounds D Wang, CE Zetterström, M Gabrielsen, KSH Beckham, JJ Tree, ... Journal of Biological Chemistry 286 (34), 29922-29931, 2011 | 111 | 2011 |
| Structural Analysis of the Complement Control Protein (CCP) Modules of GABAB Receptor 1a ONLY ONE OF THE TWO CCP MODULES IS COMPACTLY FOLDED S Blein, R Ginham, D Uhrin, BO Smith, DC Soares, S Veltel, ... Journal of Biological Chemistry 279 (46), 48292-48306, 2004 | 88 | 2004 |
| Regulation of the inflammatory response of vascular endothelial cells by EPAC1 E Parnell, BO Smith, TM Palmer, A Terrin, M Zaccolo, SJ Yarwood British journal of pharmacology 166 (2), 434-446, 2012 | 76 | 2012 |
| NMR protein structure determination in living E. coli cells using nonlinear sampling T Ikeya, A Sasaki, D Sakakibara, Y Shigemitsu, J Hamatsu, T Hanashima, ... Nature protocols 5 (6), 1051-1060, 2010 | 70 | 2010 |
| Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases C Chatrin, M Gabrielsen, L Buetow, MA Nakasone, SF Ahmed, ... Science Advances 6 (38), eabc0418, 2020 | 69 | 2020 |
| Solution structure and dynamics of the central CCP module pair of a poxvirus complement control protein CE Henderson, K Bromek, NP Mullin, BO Smith, D Uhrı́n, PN Barlow Journal of molecular biology 307 (1), 323-339, 2001 | 68 | 2001 |
| An approach to global fold determination using limited NMR data from larger proteins selectively protonated at specific residue types BO Smith, Y Ito, A Raine, S Teichmann, L Ben-Tovim, D Nietlispach, ... Journal of biomolecular NMR 8, 360-368, 1996 | 67 | 1996 |
Paul N BarlowProfessor of Structural Biology, Edinburgh UniversityVerified email at ed.ac.uk
