Alessandro Fantin
Alessandro Fantin
UCL Institute of Ophthalmology
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Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction
A Fantin, JM Vieira, G Gestri, L Denti, Q Schwarz, S Prykhozhij, F Peri, ...
Blood, The Journal of the American Society of Hematology 116 (5), 829-840, 2010
The neuropilin 1 cytoplasmic domain is required for VEGF-A-dependent arteriogenesis
A Lanahan, X Zhang, A Fantin, Z Zhuang, F Rivera-Molina, K Speichinger, ...
Developmental cell 25 (2), 156-168, 2013
NRP1 acts cell autonomously in endothelium to promote tip cell function during sprouting angiogenesis
A Fantin, JM Vieira, A Plein, L Denti, M Fruttiger, JW Pollard, C Ruhrberg
Blood, The Journal of the American Society of Hematology 121 (12), 2352-2362, 2013
Recombinant C1 inhibitor in brain ischemic injury
R Gesuete, C Storini, A Fantin, M Stravalaci, ER Zanier, F Orsini, ...
Annals of Neurology: Official Journal of the American Neurological …, 2009
The cytoplasmic domain of neuropilin 1 is dispensable for angiogenesis, but promotes the spatial separation of retinal arteries and veins
A Fantin, Q Schwarz, K Davidson, EM Normando, L Denti, C Ruhrberg
Development 138 (19), 4185-4191, 2011
Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1–dependent ABL1 activation in endothelial cells
C Raimondi, A Fantin, A Lampropoulou, L Denti, A Chikh, C Ruhrberg
Journal of Experimental Medicine 211 (6), 1167-1183, 2014
Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel roles for NRP1 in developmental and pathological angiogenesis
A Fantin, B Herzog, M Mahmoud, M Yamaji, A Plein, L Denti, C Ruhrberg, ...
Development 141 (3), 556-562, 2014
Neuropilin regulation of angiogenesis, arteriogenesis, and vascular permeability
A Plein, A Fantin, C Ruhrberg
Microcirculation 21 (4), 315-323, 2014
NRP1 regulates CDC42 activation to promote filopodia formation in endothelial tip cells
A Fantin, A Lampropoulou, G Gestri, C Raimondi, V Senatore, I Zachary, ...
Cell reports 11 (10), 1577-1590, 2015
Vascularisation of the central nervous system
M Tata, C Ruhrberg, A Fantin
Mechanisms of development 138, 26-36, 2015
The embryonic mouse hindbrain as a qualitative and quantitative model for studying the molecular and cellular mechanisms of angiogenesis
A Fantin, JM Vieira, A Plein, CH Maden, C Ruhrberg
Nature protocols 8 (2), 418-429, 2013
Dysfunctional SEMA3E signaling underlies gonadotropin-releasing hormone neuron deficiency in Kallmann syndrome
A Cariboni, V André, S Chauvet, D Cassatella, K Davidson, A Caramello, ...
The Journal of clinical investigation 125 (6), 2413-2428, 2015
Erythro-myeloid progenitors contribute endothelial cells to blood vessels
A Plein, A Fantin, L Denti, JW Pollard, C Ruhrberg
Nature 562 (7726), 223-228, 2018
Neuropilin ligands in vascular and neuronal patterning
A Fantin, CH Maden, C Ruhrberg
Biochemical Society Transactions 37 (6), 1228-1232, 2009
Neural crest–derived SEMA3C activates endothelial NRP1 for cardiac outflow tract septation
A Plein, A Calmont, A Fantin, L Denti, NA Anderson, PJ Scambler, ...
The Journal of clinical investigation 125 (7), 2661-2676, 2015
Neural crest cells in cardiovascular development
A Plein, A Fantin, C Ruhrberg
Current topics in developmental biology 111, 183-200, 2015
Neuropilin-1 mediates vascular permeability independently of vascular endothelial growth factor receptor-2 activation
L Roth, C Prahst, T Ruckdeschel, S Savant, S Weström, A Fantin, ...
Science signaling 9 (425), ra42-ra42, 2016
VEGF165-induced vascular permeability requires NRP1 for ABL-mediated SRC family kinase activation
A Fantin, A Lampropoulou, V Senatore, JT Brash, C Prahst, CA Lange, ...
Journal of Experimental Medicine 214 (4), 1049-1064, 2017
VEGF189 binds NRP1 and is sufficient for VEGF/NRP1-dependent neuronal patterning in the developing brain
M Tillo, L Erskine, A Cariboni, A Fantin, A Joyce, L Denti, C Ruhrberg
Development 142 (2), 314-319, 2015
NRP1 function and targeting in neurovascular development and eye disease
C Raimondi, JT Brash, A Fantin, C Ruhrberg
Progress in retinal and eye research 52, 64-83, 2016
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