Open3DQSAR: a new open-source software aimed at high-throughput chemometric analysis of molecular interaction fields P Tosco, T Balle Journal of molecular modeling 17, 201-208, 2011 | 177 | 2011 |
Unraveling the high-and low-sensitivity agonist responses of nicotinic acetylcholine receptors K Harpsøe, PK Ahring, JK Christensen, ML Jensen, D Peters, T Balle Journal of Neuroscience 31 (30), 10759-10766, 2011 | 161 | 2011 |
Open3DALIGN: an open-source software aimed at unsupervised ligand alignment P Tosco, T Balle, F Shiri Journal of computer-aided molecular design 25, 777-783, 2011 | 135 | 2011 |
A Unified Model of the GABAA Receptor Comprising Agonist and Benzodiazepine Binding Sites R Bergmann, K Kongsbak, PL Sørensen, T Sander, T Balle PloS one 8 (1), e52323, 2013 | 122 | 2013 |
Synthesis and Structure− Affinity Relationship Investigations of 5-Heteroaryl-Substituted Analogues of the Antipsychotic Sertindole. A New Class of Highly Selective α1 … T Balle, J Perregaard, MT Ramirez, AK Larsen, KK Søby, T Liljefors, ... Journal of medicinal chemistry 46 (2), 265-283, 2003 | 78 | 2003 |
GABAA receptor partial agonists and antagonists: structure, binding mode, and pharmacology J Krall, T Balle, N Krogsgaard-Larsen, TE Sørensen, ... Advances in pharmacology 72, 201-227, 2015 | 59 | 2015 |
Rational design of α-conotoxin analogues targeting α7 nicotinic acetylcholine receptors C Armishaw, AA Jensen, T Balle, RJ Clark, K Harpsøe, C Skonberg, ... Journal of biological chemistry 284 (14), 9498-9512, 2009 | 59 | 2009 |
Liquid lipases for enzymatic concentration of n-3 polyunsaturated fatty acids in monoacylglycerols via ethanolysis: Catalytic specificity and parameterization Y He, J Li, S Kodali, T Balle, B Chen, Z Guo Bioresource Technology 224, 445-456, 2017 | 58 | 2017 |
Innate immunity and inflammation post-stroke: an α7-nicotinic agonist perspective S Neumann, NJ Shields, T Balle, M Chebib, AN Clarkson International Journal of Molecular Sciences 16 (12), 29029-29046, 2015 | 58 | 2015 |
Design, synthesis, and biological evaluation of Erythrina alkaloid analogues as neuronal nicotinic acetylcholine receptor antagonists F Crestey, AA Jensen, M Borch, JT Andreasen, J Andersen, T Balle, ... Journal of Medicinal Chemistry 56 (23), 9673-9682, 2013 | 57 | 2013 |
Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine α4β2 receptors LAH Rohde, PK Ahring, ML Jensen, EØ Nielsen, D Peters, C Helgstrand, ... Journal of Biological Chemistry 287 (6), 4248-4259, 2012 | 54 | 2012 |
Molecular recognition of the neurotransmitter acetylcholine by an acetylcholine binding protein reveals determinants of binding to nicotinic acetylcholine receptors JA Olsen, T Balle, M Gajhede, PK Ahring, JS Kastrup PloS one 9 (3), e91232, 2014 | 51 | 2014 |
Two distinct allosteric binding sites at α4β2 nicotinic acetylcholine receptors revealed by NS206 and NS9283 give unique insights to binding activity-associated linkage at Cys … JA Olsen, JS Kastrup, D Peters, M Gajhede, T Balle, PK Ahring Journal of Biological Chemistry 288 (50), 35997-36006, 2013 | 51 | 2013 |
G Protein- and Agonist-Bound Serotonin 5-HT2A Receptor Model Activated by Steered Molecular Dynamics Simulations V Ísberg, T Balle, T Sander, FS Jørgensen, DE Gloriam Journal of chemical information and modeling 51 (2), 315-325, 2011 | 50 | 2011 |
Structural studies of nicotinic acetylcholine receptors: Using acetylcholine‐binding protein as a structural surrogate A Shahsavar, M Gajhede, JS Kastrup, T Balle Basic & clinical pharmacology & toxicology 118 (6), 399-407, 2016 | 47 | 2016 |
Crystal Structure of Lymnaea stagnalis AChBP Complexed with the Potent nAChR Antagonist DHβE Suggests a Unique Mode of Antagonism A Shahsavar, JS Kastrup, EØ Nielsen, JL Kristensen, M Gajhede, T Balle Public Library of Science 7 (8), e40757, 2012 | 47 | 2012 |
Galantamine is not a positive allosteric modulator of human α4β2 or α7 nicotinic acetylcholine receptors NM Kowal, PK Ahring, VWY Liao, DC Indurti, BS Harvey, SM O'Connor, ... British journal of pharmacology 175 (14), 2911-2925, 2018 | 46 | 2018 |
Probing the role of backbone hydrogen bonds in protein–peptide interactions by amide-to-ester mutations JNN Eildal, G Hultqvist, T Balle, N Stuhr-Hansen, S Padrah, S Gianni, ... Journal of the American Chemical Society 135 (35), 12998-13007, 2013 | 46 | 2013 |
New insights into the GABAA receptor structure and orthosteric ligand binding: Receptor modeling guided by experimental data T Sander, B Frølund, AT Bruun, I Ivanov, JA McCammon, T Balle Proteins: Structure, Function, and Bioinformatics 79 (5), 1458-1477, 2011 | 46 | 2011 |
Structural and functional studies of the modulator NS9283 reveal agonist-like mechanism of action at α4β2 nicotinic acetylcholine receptors JA Olsen, PK Ahring, JS Kastrup, M Gajhede, T Balle Journal of Biological Chemistry 289 (36), 24911-24921, 2014 | 43 | 2014 |