| Axonal transport and neurological disease JN Sleigh, AM Rossor, AD Fellows, AP Tosolini, G Schiavo Nature Reviews Neurology 15 (12), 691-703, 2019 | 226 | 2019 |
| Systemic peptide-mediated oligonucleotide therapy improves long-term survival in spinal muscular atrophy SM Hammond, G Hazell, F Shabanpoor, AF Saleh, M Bowerman, ... Proceedings of the National Academy of Sciences 113 (39), 10962-10967, 2016 | 188 | 2016 |
| The contribution of mouse models to understanding the pathogenesis of spinal muscular atrophy JN Sleigh, TH Gillingwater, K Talbot Disease models & mechanisms 4 (4), 457-467, 2011 | 144 | 2011 |
| A simple, step-by-step dissection protocol for the rapid isolation of mouse dorsal root ganglia JN Sleigh, GA Weir, G Schiavo BMC research notes 9 (1), 1-7, 2016 | 140 | 2016 |
| Conserved genes act as modifiers of invertebrate SMN loss of function defects M Dimitriadi, JN Sleigh, A Walker, HC Chang, A Sen, G Kalloo, J Harris, ... PLoS genetics 6 (10), e1001172, 2010 | 113 | 2010 |
| Vascular defects and spinal cord hypoxia in spinal muscular atrophy E Somers, RD Lees, K Hoban, JN Sleigh, H Zhou, F Muntoni, K Talbot, ... Annals of neurology 79 (2), 217-230, 2016 | 90 | 2016 |
| Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition AL Kalinski, AN Kar, J Craver, AP Tosolini, JN Sleigh, SJ Lee, ... Journal of Cell Biology 218 (6), 1871-1890, 2019 | 85 | 2019 |
| Neuromuscular junction maturation defects precede impaired lower motor neuron connectivity in Charcot–Marie–Tooth type 2D mice JN Sleigh, SJ Grice, RW Burgess, K Talbot, MZ Cader Human Molecular Genetics 23 (10), 2639-2650, 2014 | 79 | 2014 |
| Morphological analysis of neuromuscular junction development and degeneration in rodent lumbrical muscles JN Sleigh, RW Burgess, TH Gillingwater, MZ Cader Journal of neuroscience methods 227, 159-165, 2014 | 77 | 2014 |
| Chondrolectin affects cell survival and neuronal outgrowth in in vitro and in vivo models of spinal muscular atrophy JN Sleigh, A Barreiro-Iglesias, PL Oliver, A Biba, T Becker, KE Davies, ... Human molecular genetics 23 (4), 855-869, 2014 | 77 | 2014 |
| Synaptic deficits at neuromuscular junctions in two mouse models of Charcot–Marie–Tooth type 2d EL Spaulding, JN Sleigh, KH Morelli, MJ Pinter, RW Burgess, KL Seburn Journal of Neuroscience 36 (11), 3254-3267, 2016 | 72 | 2016 |
| Trk receptor signaling and sensory neuron fate are perturbed in human neuropathy caused by Gars mutations JN Sleigh, JM Dawes, SJ West, N Wei, EL Spaulding, A Gómez-Martín, ... Proceedings of the National Academy of Sciences 114 (16), E3324-E3333, 2017 | 71 | 2017 |
| A novel Caenorhabditis elegans allele, smn-1(cb131), mimicking a mild form of spinal muscular atrophy, provides a convenient drug screening platform … JN Sleigh, SD Buckingham, B Esmaeili, M Viswanathan, E Cuppen, ... Human molecular genetics 20 (2), 245-260, 2011 | 70 | 2011 |
| Antisense oligonucleotides and other genetic therapies made simple AM Rossor, MM Reilly, JN Sleigh Practical Neurology 18 (2), 126-131, 2018 | 62 | 2018 |
| Mice carrying ALS mutant TDP-43, but not mutant FUS, display in vivo defects in axonal transport of signaling endosomes JN Sleigh, AP Tosolini, D Gordon, A Devoy, P Fratta, EMC Fisher, ... Cell Reports 30 (11), 3655-3662. e2, 2020 | 59* | 2020 |
| Loss of Lrsam1, a Charcot-Marie-Tooth disease-associated E3 ubiquitin ligase, sensitizes peripheral axons to degeneration in mice LP Bogdanik, JN Sleigh, C Tian, ME Samuels, K Bedard, KL Seburn, ... | 57* | 2013 |
| Dominant, toxic gain-of-function mutations in gars lead to non-cell autonomous neuropathology SJ Grice, JN Sleigh, WW Motley, JL Liu, RW Burgess, K Talbot, MZ Cader Human Molecular Genetics 24 (15), 4397-4406, 2015 | 55 | 2015 |
| Motor neuron gene therapy: lessons from spinal muscular atrophy for amyotrophic lateral sclerosis AP Tosolini, JN Sleigh Frontiers in molecular neuroscience 10, 405, 2017 | 51 | 2017 |
| In vivo imaging of axonal transport in murine motor and sensory neurons KL Gibbs, B Kalmar, JN Sleigh, L Greensmith, G Schiavo Journal of Neuroscience Methods 257, 26-33, 2016 | 50 | 2016 |
| Overexpression of survival motor neuron improves neuromuscular function and motor neuron survival in mutant SOD1 mice BJ Turner, N Alfazema, RK Sheean, JN Sleigh, KE Davies, MK Horne, ... Neurobiology of aging 35 (4), 906-915, 2014 | 47 | 2014 |
Giampietro SchiavoUCL Queen Square Institute of NeurologyVerified email at ucl.ac.uk
