| ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL KE Ewings, K Hadfield-Moorhouse, CM Wiggins, JA Wickenden, ... The EMBO journal 26 (12), 2856-2867, 2007 | 217 | 2007 |
| Cigarette smoke prevents apoptosis through inhibition of caspase activation and induces necrosis JA Wickenden, MCH Clarke, AG Rossi, I Rahman, SP Faux, K Donaldson, ... American journal of respiratory cell and molecular biology 29 (5), 562-570, 2003 | 170 | 2003 |
| Key signalling nodes in mammary gland development and cancer. Signalling downstream of PI3 kinase in mammary epithelium: a play in 3 Akts JA Wickenden, CJ Watson Breast cancer research 12 (2), 1-9, 2010 | 125 | 2010 |
| Conditional deletion of Stat3 in mammary epithelium impairs the acute phase response and modulates immune cell numbers during post‐lactational regression K Hughes, JA Wickenden, JE Allen, CJ Watson The Journal of pathology 227 (1), 106-117, 2012 | 108 | 2012 |
| Colorectal cancer cells with the BRAFV600E mutation are addicted to the ERK1/2 pathway for growth factor-independent survival and repression of BIM JA Wickenden, H Jin, M Johnson, AS Gillings, C Newson, M Austin, ... Oncogene 27 (57), 7150-7161, 2008 | 95 | 2008 |
| Differential Reprogramming of Isogenic Colorectal Cancer Cells by Distinct Activating KRAS Mutations DE Hammond, CJ Mageean, EV Rusilowicz, JA Wickenden, MJ Clague, ... Journal of proteome research 14 (3), 1535-1546, 2015 | 79 | 2015 |
| Role of histone acetylation in transcriptional regulation and promotion of inflammatory process in patients with chronic obstructive pulmonary disease P Szulakowski, E Drost, LA Jimenez, JA Wickenden, AJ Crowther, ... Am J Respir Crit Care Med 169, A275, 2004 | 11 | 2004 |
| Molecular biology of breast cancer MM Caffarel, S Pensa, JA Wickenden, CJ Watson eLS, 1-9, 2016 | 10 | 2016 |
| A medium-throughput single cell CRISPR-Cas9 assay to assess gene essentiality AR Grassian, TME Scales, SK Knutson, KW Kuntz, NJ McCarthy, ... Biological procedures online 17 (1), 1-10, 2015 | 7 | 2015 |
| Investigating KRAS synthetic lethal/co-dependency interactions using siRNA and CRISPR SF Scrace, E Tsonou, P Russell, JA Wickenden, S Lawo, TM Scales, ... Cancer Research 75 (15_Supplement), 700-700, 2015 | 1 | 2015 |
| Cigarette smoke condensate inhibits apoptosis and promotes necrosis JA Wickenden, MCH Clarke, K Donaldson, W MacNee EUROPEAN RESPIRATORY JOURNAL 22, 50S-50S, 2003 | 1 | 2003 |
| The Development of a Highly Multiplexed FFPE Reference Standard for Somatic Cancer Panels P Nagarajan, S Constantine, J Wickenden JOURNAL OF MOLECULAR DIAGNOSTICS 21 (6), 1206-1206, 2019 | | 2019 |
| Development and evaluation of cell line-derived FFPE reference material for MSI assay validation T Matsusaka, EM Surmann, S Constantine, H Child, J Wickenden Cancer Research 79 (13_Supplement), 4221-4221, 2019 | | 2019 |
| How Variabilities in Tumor Liquid Biopsy Workflows Can Be Tackled with cfDNA Reference Standards K Wilczynska, Y Naiyachit, A Herreboudt, J Wickenden, EM Surmann JOURNAL OF MOLECULAR DIAGNOSTICS 20 (3), S27-S27, 2018 | | 2018 |
| Comparison of cfDNA Reference Material Prepared using Enzymatic Fragmentation or Sonication for the Validation of Liquid Biopsy Assays A Mele, H Child, K Wilczynska, CPS Chacko, J Wickenden | | 2018 |
| Wild-type IDH1: A molecular target in IDH1 mutant cancers JA Wickenden, P Russell, A Smith, T Henley, J Elliott, D Gitterman, ... Cancer Research 74 (19_Supplement), 4620-4620, 2014 | | 2014 |
| 527 Is CRAF required for the maintenance of KRAS mutant non-small cell lung cancer? P Russell, J Wickenden, K Cadwallader, S Maguire, J Joel, M Stockdale, ... European Journal of Cancer, 171, 2014 | | 2014 |
| Mammary Epithelial Stat3 Expression Modulates the Inflammatory Signature of the Gland During Regression Post-weaning K Hughes, JA Wickenden, CJ Watson JOURNAL OF PATHOLOGY 226, S11-S11, 2012 | | 2012 |
| Pathogenesis of Emphysema: Molecular Mechanisms Underlying Cigarette Smoke-induced Cell Death JA Wickenden University of Edinburgh, 2005 | | 2005 |
| Cigarette smoke and oxidative stress alter histone acetylation and deacetylation in alveolar epithelial cells: potential mechanism in inflammatory gene transcription I Rahman, FM Moodie, JA Wickenden, JA Marwick, LA Jimenez, ... EUROPEAN RESPIRATORY JOURNAL 22, 44S-44S, 2003 | | 2003 |
Simon CookSignalling Programme, The Babraham InstituteVerified email at babraham.ac.uk
