Kerstin Nina Timm
Kerstin Nina Timm
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Hyperpolarized singlet lifetimes of pyruvate in human blood and in the mouse
I Marco‐Rius, MCD Tayler, MI Kettunen, TJ Larkin, KN Timm, EM Serrao, ...
NMR in Biomedicine 26 (12), 1696-1704, 2013
Hyperpolarized [U‐2H, U‐13C]Glucose reports on glycolytic and pentose phosphate pathway activity in EL4 tumors and glycolytic activity in yeast cells
KN Timm, J Hartl, MA Keller, DE Hu, MI Kettunen, TB Rodrigues, M Ralser, ...
Magnetic resonance in medicine 74 (6), 1543-1547, 2015
Detection of transgene expression using hyperpolarized 13C urea and diffusion‐weighted magnetic resonance spectroscopy
PS Patrick, MI Kettunen, SS Tee, TB Rodrigues, E Serrao, KN Timm, ...
Magnetic resonance in medicine 73 (4), 1401-1406, 2015
Fatty acids prevent hypoxia-inducible factor-1α signaling through decreased succinate in diabetes
MS Dodd, ML Sousa Fialho, CN Montes Aparicio, M Kerr, KN Timm, ...
JACC: Basic to Translational Science 3 (4), 485-498, 2018
Assessing oxidative stress in tumors by measuring the rate of hyperpolarized [1-13C] dehydroascorbic acid reduction using 13C magnetic resonance spectroscopy
KN Timm, DE Hu, M Williams, AJ Wright, MI Kettunen, BWC Kennedy, ...
Journal of Biological Chemistry 292 (5), 1737-1748, 2017
The role of AMPK activation for cardioprotection in doxorubicin-induced cardiotoxicity
KN Timm, DJ Tyler
Cardiovascular drugs and therapy 34 (2), 255-269, 2020
Imaging tumor metabolism to assess disease progression and treatment response
KN Timm, BWC Kennedy, KM Brindle
Clinical Cancer Research 22 (21), 5196-5203, 2016
13C magnetic resonance spectroscopic imaging of hyperpolarized [1‐13C, U‐2H5] ethanol oxidation can be used to assess aldehyde dehydrogenase activity in …
P Dzien, MI Kettunen, I Marco‐Rius, EM Serrao, TB Rodrigues, TJ Larkin, ...
Magnetic resonance in medicine 73 (5), 1733-1740, 2015
Cardiac applications of hyperpolarised magnetic resonance
KN Timm, JJ Miller, JA Henry, DJ Tyler
Progress in nuclear magnetic resonance spectroscopy 106, 66-87, 2018
13C magnetic resonance spectroscopy measurements with hyperpolarized [1‐13C] pyruvate can be used to detect the expression of transgenic pyruvate …
P Dzien, SS Tee, MI Kettunen, SK Lyons, TJ Larkin, KN Timm, DE Hu, ...
Magnetic resonance in medicine 76 (2), 391-401, 2016
Rescue of myocardial energetic dysfunction in diabetes through the correction of mitochondrial hyperacetylation by honokiol
M Kerr, JJ Miller, D Thapa, S Stiewe, KN Timm, CNM Aparicio, I Scott, ...
JCI insight 5 (17), 2020
Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI
KN Timm, C Perera, V Ball, JA Henry, JJ Miller, M Kerr, JA West, ...
Communications biology 3 (1), 1-10, 2020
Hyperpolarized magnetic resonance shows that the anti‐ischemic drug meldonium leads to increased flux through pyruvate dehydrogenase in vivo resulting in improved post‐ischemic …
D Savic, V Ball, L Holzner, D Hauton, KN Timm, MK Curtis, LC Heather, ...
NMR in Biomedicine 34 (4), e4471, 2021
Probing hepatic metabolism of [2-13 C] dihydroxyacetone in vivo with 1 H-decoupled hyperpolarized 13 C-MR
I Marco-Rius, AJ Wright, D Hu, D Savic, JJ Miller, KN Timm, D Tyler, ...
Magnetic Resonance Materials in Physics, Biology and Medicine 34 (1), 49-56, 2021
A 3D hybrid‐shot spiral sequence for hyperpolarized imaging
A Tyler, JYC Lau, V Ball, KN Timm, T Zhou, DJ Tyler, JJ Miller
Magnetic Resonance in Medicine 85 (2), 790-801, 2021
Rapid and B1-insensitive absolute quantification of the CK Flux reaction with dual-band quasi-adiabatic saturation transfer with Optimal Control
JJ Miller, L Valkovic, M Kerr, KN Timm, W Watson, JYC Lau, A Tyler, ...
Wiley, 2020
17: Magnetic resonance imaging of tumour metabolism
KM Brindle, DE Hu, TB Rodrigues, EM Serrao, KN Timm
European Journal of Cancer, S5-S6, 2014
Rapid,‐insensitive, dual‐band quasi‐adiabatic saturation transfer with optimal control for complete quantification of myocardial ATP flux
JJ Miller, L Valkovič, M Kerr, KN Timm, WD Watson, JYC Lau, A Tyler, ...
Magnetic resonance in medicine 85 (6), 2978-2991, 2021
Nicotinic acid receptor agonists impair myocardial contractility by energy starvation
WD Watson, KN Timm, AJ Lewis, JJJ Miller, Y Emmanuel, K Clarke, ...
The FASEB Journal 34 (11), 14878-14891, 2020
Assessing the optimal preparation strategy to minimize the variability of cardiac pyruvate dehydrogenase flux measurements with hyperpolarized MRS
KN Timm, A Apps, JJ Miller, V Ball, CR Chong, MS Dodd, DJ Tyler
NMR in Biomedicine 31 (9), e3992, 2018
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