Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection RE Lanford, ES Hildebrandt-Eriksen, A Petri, R Persson, M Lindow, ... Science 327 (5962), 198-201, 2010 | 2133 | 2010 |
LNA-mediated microRNA silencing in non-human primates J Elmén, M Lindow, S Schütz, M Lawrence, A Petri, S Obad, M Lindholm, ... Nature 452 (7189), 896-899, 2008 | 2008 | 2008 |
Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells LB Frankel, NR Christoffersen, A Jacobsen, M Lindow, A Krogh, AH Lund Journal of Biological Chemistry 283 (2), 1026-1033, 2008 | 1466 | 2008 |
Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver J Elmen, M Lindow, A Silahtaroglu, M Bak, M Christensen, ... Nucleic acids research 36 (4), 1153-1162, 2008 | 850 | 2008 |
Silencing of microRNA families by seed-targeting tiny LNAs S Obad, CO dos Santos, A Petri, M Heidenblad, O Broom, C Ruse, C Fu, ... Nature genetics 43 (4), 371-378, 2011 | 736 | 2011 |
Inhibition of microRNA function by antimiR oligonucleotides J Stenvang, A Petri, M Lindow, S Obad, S Kauppinen Silence 3, 1-17, 2012 | 627 | 2012 |
The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line Nature genetics 41 (5), 553-562, 2009 | 418 | 2009 |
Discovering the first microRNA-targeted drug M Lindow, S Kauppinen Journal of Cell Biology 199 (3), 407-412, 2012 | 397 | 2012 |
Brain expressed microRNAs implicated in schizophrenia etiology T Hansen, L Olsen, M Lindow, KD Jakobsen, H Ullum, E Jonsson, ... PloS one 2 (9), e873, 2007 | 324 | 2007 |
microRNA-9 targets the long non-coding RNA MALAT1 for degradation in the nucleus E Leucci, F Patella, J Waage, K Holmstrøm, M Lindow, B Porse, ... Scientific reports 3 (1), 2535, 2013 | 289 | 2013 |
The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice M Castoldi, MV Spasic, S Altamura, J Elmén, M Lindow, J Kiss, J Stolte, ... The Journal of clinical investigation 121 (4), 1386-1396, 2011 | 278 | 2011 |
MicroRNA profiling identifies microRNA-155 as an adverse mediator of cardiac injury and dysfunction during acute viral myocarditis MF Corsten, A Papageorgiou, W Verhesen, P Carai, M Lindow, S Obad, ... Circulation research 111 (4), 415-425, 2012 | 246 | 2012 |
The utility of LNA in microRNA-based cancer diagnostics and therapeutics J Stenvang, AN Silahtaroglu, M Lindow, J Elmen, S Kauppinen Seminars in cancer biology 18 (2), 89-102, 2008 | 233 | 2008 |
Experimental identification of microRNA-140 targets by silencing and overexpressing miR-140 FE Nicolas, H Pais, F Schwach, M Lindow, S Kauppinen, V Moulton, ... Rna 14 (12), 2513-2520, 2008 | 151 | 2008 |
MicroRNA silencing in primates: towards development of novel therapeutics A Petri, M Lindow, S Kauppinen Cancer research 69 (2), 393-395, 2009 | 130 | 2009 |
MicroRNAs S Obad, S Kauppinen, J Elmen, M Lindow, M Heidenblad US Patent 8,288,356, 2012 | 127 | 2012 |
Principles and limitations of computational microRNA gene and target finding M Lindow, J Gorodkin DNA and cell biology 26 (5), 339-351, 2007 | 119 | 2007 |
Computational evidence for hundreds of non-conserved plant microRNAs M Lindow, A Krogh BMC genomics 6, 1-9, 2005 | 117 | 2005 |
Hepatotoxic potential of therapeutic oligonucleotides can be predicted from their sequence and modification pattern PH Hagedorn, V Yakimov, S Ottosen, S Kammler, NF Nielsen, AM Høg, ... nucleic acid therapeutics 23 (5), 302-310, 2013 | 97 | 2013 |
Assessing unintended hybridization-induced biological effects of oligonucleotides M Lindow, HP Vornlocher, D Riley, DJ Kornbrust, J Burchard, LO Whiteley, ... Nature biotechnology 30 (10), 920-923, 2012 | 95 | 2012 |