Yohei Ohashi
Yohei Ohashi
Laboratory of Molecular Biology, Medical Research Council
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Modulation of phospholipid signaling by GLABRA2 in root-hair pattern formation
Y Ohashi, A Oka, R Rodrigues-Pousada, M Possenti, I Ruberti, G Morelli, ...
Science 300 (5624), 1427-1430, 2003
Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes
K Rostislavleva, N Soler, Y Ohashi, L Zhang, E Pardon, JE Burke, ...
Science 350 (6257), aac7365, 2015
Membrane delivery to the yeast autophagosome from the Golgi–endosomal system
Y Ohashi, S Munro
Molecular biology of the cell 21 (22), 3998-4008, 2010
The A-Type Cyclin CYCA2;3 Is a Key Regulator of Ploidy Levels in Arabidopsis Endoreduplication
KK Imai, Y Ohashi, T Tsuge, T Yoshizumi, M Matsui, A Oka, T Aoyama
The Plant Cell 18 (2), 382-396, 2006
GLABRA2 directly suppresses basic helix-loop-helix transcription factor genes with diverse functions in root hair development
Q Lin, Y Ohashi, M Kato, T Tsuge, H Gu, LJ Qu, T Aoyama
The Plant Cell 27 (10), 2894-2906, 2015
Entopically additive expression of GLABRA2 alters the frequency and spacing of trichome initiation
Y Ohashi, A Oka, I Ruberti, G Morelli, T Aoyama
The Plant Journal 29 (3), 359-369, 2002
VPS34 complexes from a structural perspective
Y Ohashi, S Tremel, RL Williams
Journal of lipid research 60 (2), 229-241, 2019
Tor forms a dimer through an N-terminal helical solenoid with a complex topology
D Baretić, A Berndt, Y Ohashi, CM Johnson, RL Williams
Nature communications 7 (1), 11016, 2016
Characterization of Atg38 and NRBF2, a fifth subunit of the autophagic Vps34/PIK3C3 complex
Y Ohashi, N Soler, M García Ortegón, L Zhang, ML Kirsten, O Perisic, ...
Autophagy 12 (11), 2129-2144, 2016
Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes
S Tremel, Y Ohashi, DR Morado, J Bertram, O Perisic, LTL Brandt, ...
Nature communications 12 (1), 1564, 2021
Guidelines for the use and interpretation of assays for monitoring autophagy 1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
Autophagy 17 (1), 1-382, 2021
Phosphoproteomic identification of ULK substrates reveals VPS15‐dependent ULK/VPS34 interplay in the regulation of autophagy
TJ Mercer, Y Ohashi, S Boeing, HBJ Jefferies, S De Tito, H Flynn, ...
The EMBO Journal 40 (14), e105985, 2021
Membrane characteristics tune activities of endosomal and autophagic human VPS34 complexes
Y Ohashi, S Tremel, GR Masson, L McGinney, J Boulanger, ...
Elife 9, 2020
An upstream region of the Arabidopsis thaliana CDKA; 1 (CDC2aAt) gene directs transcription during trichome development
Y Imajuku, Y Ohashi, T Aoyama, K Goto, A Oka
Plant Molecular Biology 46, 205-213, 2001
Activation mechanisms of the VPS34 complexes
Y Ohashi
Cells 10 (11), 3124, 2021
The G-protein Rab5A activates VPS34 complex II, a class III PI3K, by a dual regulatory mechanism
TC Buckles, Y Ohashi, S Tremel, SH McLaughlin, E Pardon, J Steyaert, ...
Biophysical Journal 119 (11), 2205-2218, 2020
Development of selective inhibitors of phosphatidylinositol 3-kinase C2α
WT Lo, H Belabed, M Kücükdisli, J Metag, Y Roske, P Prokofeva, ...
Nature chemical biology 19 (1), 18-27, 2023
Class III phosphatidylinositol 3-kinase complex I subunit NRBF2/Atg38-from cell and structural biology to health and disease
Y Ohashi
Autophagy 17 (12), 3897-3907, 2021
Unsaturation, curvature and charge: effects of membrane parameters on PIK3C3/VPS34-containing complexes
Y Ohashi, S Tremel, RL Williams
Autophagy 17 (3), 823-825, 2021
Arabidopsis PLDζ1 and PLDζ2 localize to post-Golgi membrane compartments in a partially overlapping manner
R Shimamura, Y Ohashi, YY Taniguchi, M Kato, T Tsuge, T Aoyama
Plant molecular biology, 1-19, 2022
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