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A. Marieke Oudelaar
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Genetic dissection of the α-globin super-enhancer in vivo
D Hay, JR Hughes, C Babbs, JOJ Davies, BJ Graham, LLP Hanssen, ...
Nature genetics 48 (8), 895-903, 2016
3672016
Tissue-specific CTCF–cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo
LLP Hanssen, MT Kassouf, AM Oudelaar, D Biggs, C Preece, DJ Downes, ...
Nature cell biology 19 (8), 952-961, 2017
2132017
The relationship between genome structure and function
AM Oudelaar, DR Higgs
Nature Reviews Genetics 22 (3), 154-168, 2021
1842021
Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains
AM Oudelaar, JOJ Davies, LLP Hanssen, JM Telenius, R Schwessinger, ...
Nature genetics 50 (12), 1744-1751, 2018
1772018
How best to identify chromosomal interactions: a comparison of approaches
JOJ Davies, AM Oudelaar, DR Higgs, JR Hughes
Nature methods 14 (2), 125-134, 2017
1512017
DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation
L Godfrey, NT Crump, R Thorne, IJ Lau, E Repapi, D Dimou, AL Smith, ...
Nature communications 10 (1), 2803, 2019
1212019
DeepC: predicting 3D genome folding using megabase-scale transfer learning
R Schwessinger, M Gosden, D Downes, RC Brown, AM Oudelaar, ...
Nature Methods 17 (11), 1118-1124, 2020
1182020
Defining genome architecture at base-pair resolution
P Hua, M Badat, LLP Hanssen, LD Hentges, N Crump, DJ Downes, ...
Nature 595 (7865), 125-129, 2021
1132021
Dynamics of the 4D genome during in vivo lineage specification and differentiation
AM Oudelaar, RA Beagrie, M Gosden, S de Ornellas, E Georgiades, ...
Nature Communications 11 (1), 1-12, 2020
902020
A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions
JM Brown, NA Roberts, B Graham, D Waithe, C Lagerholm, JM Telenius, ...
Nature communications 9 (1), 3849, 2018
732018
A revised model for promoter competition based on multi-way chromatin interactions at the α-globin locus
AM Oudelaar, CL Harrold, LLP Hanssen, JM Telenius, DR Higgs, ...
Nature communications 10 (1), 1-8, 2019
692019
Analysis of sub-kilobase chromatin topology reveals nano-scale regulatory interactions with variable dependence on cohesin and CTCF
A Aljahani, P Hua, MA Karpinska, K Quililan, JOJ Davies, AM Oudelaar
Nature communications 13 (1), 2139, 2022
582022
Enhancers predominantly regulate gene expression during differentiation via transcription initiation
MSC Larke, R Schwessinger, T Nojima, J Telenius, RA Beagrie, ...
Molecular Cell, 2021
392021
A Dynamic Folded Hairpin Conformation Is Associated with α-Globin Activation in Erythroid Cells
AM Chiariello, S Bianco, AM Oudelaar, A Esposito, C Annunziatella, ...
Cell Reports 30 (7), 2125-2135. e5, 2020
362020
High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale
DJ Downes, RA Beagrie, ME Gosden, J Telenius, SJ Carpenter, ...
Nature Communications 12 (1), 1-15, 2021
322021
The Mediator complex regulates enhancer-promoter interactions
S Ramasamy, A Aljahani, MA Karpinska, TBN Cao, T Velychko, JN Cruz, ...
Nature Structural & Molecular Biology 30 (7), 991-1000, 2023
302023
Robust detection of chromosomal interactions from small numbers of cells using low-input Capture-C
AM Oudelaar, JOJ Davies, DJ Downes, DR Higgs, JR Hughes
Nucleic acids research 45 (22), e184-e184, 2017
292017
Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture
DJ Downes, AL Smith, MA Karpinska, T Velychko, K Rue-Albrecht, D Sims, ...
Nature Protocols 17 (2), 445-475, 2022
252022
Reactivation of a developmentally silenced embryonic globin gene
AJ King, D Songdej, DJ Downes, RA Beagrie, S Liu, M Buckley, P Hua, ...
Nature Communications 12 (1), 1-15, 2021
252021
The mouse alpha-globin cluster: a paradigm for studying genome regulation and organization
AM Oudelaar, RA Beagrie, MT Kassouf, DR Higgs
Current Opinion in Genetics & Development 67, 18-24, 2021
222021
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