iCLIP: protein–RNA interactions at nucleotide resolution I Huppertz, J Attig, A D’Ambrogio, LE Easton, CR Sibley, Y Sugimoto, ... Methods 65 (3), 274-287, 2014 | 494 | 2014 |
Lessons from non-canonical splicing CR Sibley, L Blazquez, J Ule Nature Reviews Genetics 17 (7), 407-421, 2016 | 317 | 2016 |
The interaction of PRC2 with RNA or chromatin is mutually antagonistic M Beltran, CM Yates, L Skalska, M Dawson, FP Reis, K Viiri, CL Fisher, ... Genome research 26 (7), 896-907, 2016 | 255 | 2016 |
Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS CE Hall, Z Yao, M Choi, GE Tyzack, A Serio, R Luisier, J Harley, E Preza, ... Cell reports 19 (9), 1739-1749, 2017 | 198 | 2017 |
Recursive splicing in long vertebrate genes CR Sibley, W Emmett, L Blazquez, A Faro, N Haberman, M Briese, ... Nature 521 (7552), 371-375, 2015 | 169 | 2015 |
Novel RNA-based strategies for therapeutic gene silencing CR Sibley, Y Seow, MJA Wood molecular Therapy 18 (3), 466-476, 2010 | 166 | 2010 |
The biogenesis and characterization of mammalian microRNAs of mirtron origin CR Sibley, Y Seow, S Saayman, KK Dijkstra, S El Andaloussi, ... Nucleic acids research 40 (1), 438-448, 2012 | 142 | 2012 |
Mirtrons, an emerging class of atypical miRNA HJ Curtis, CR Sibley, MJA Wood Wiley Interdisciplinary Reviews: RNA 3 (5), 617-632, 2012 | 121 | 2012 |
A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models GE Tyzack, CE Hall, CR Sibley, T Cymes, S Forostyak, G Carlino, ... Nature communications 8 (1), 1164, 2017 | 120 | 2017 |
Regulation of constitutive and alternative mRNA splicing across the human transcriptome by PRPF8 is determined by 5′ splice site strength VO Wickramasinghe, M Gonzàlez-Porta, D Perera, AR Bartolozzi, ... Genome biology 16, 1-21, 2015 | 101 | 2015 |
Insights into the design and interpretation of iCLIP experiments N Haberman, I Huppertz, J Attig, J König, Z Wang, C Hauer, MW Hentze, ... Genome biology 18, 1-21, 2017 | 98 | 2017 |
P-TEFb activation by RBM7 shapes a pro-survival transcriptional response to genotoxic stress A Bugai, AJC Quaresma, CC Friedel, T Lenasi, R Düster, CR Sibley, ... Molecular cell 74 (2), 254-267. e10, 2019 | 84 | 2019 |
Exon junction complex shapes the transcriptome by repressing recursive splicing L Blazquez, W Emmett, R Faraway, JMB Pineda, S Bajew, A Gohr, ... Molecular cell 72 (3), 496-509. e9, 2018 | 84 | 2018 |
Silencing of Parkinson's disease-associated genes with artificial mirtron mimics of miR-1224 CR Sibley, Y Seow, H Curtis, MS Weinberg, MJA Wood Nucleic acids research 40 (19), 9863-9875, 2012 | 49 | 2012 |
Transcript-specific characteristics determine the contribution of endo-and exonucleolytic decay pathways during the degradation of nonsense-mediated decay substrates F Ottens, V Boehm, CR Sibley, J Ule, NH Gehring Rna 23 (8), 1224-1236, 2017 | 41 | 2017 |
CLIPing the brain: Studies of protein–RNA interactions important for neurodegenerative disorders M Modic, J Ule, CR Sibley Molecular and Cellular Neuroscience 56, 429-435, 2013 | 40 | 2013 |
A systems view of spliceosomal assembly and branchpoints with iCLIP M Briese, N Haberman, CR Sibley, R Faraway, AS Elser, AM Chakrabarti, ... Nature structural & molecular biology 26 (10), 930-940, 2019 | 36 | 2019 |
Astrocytes display cell autonomous and diverse early reactive states in familial amyotrophic lateral sclerosis DM Taha, BE Clarke, CE Hall, GE Tyzack, OJ Ziff, L Greensmith, B Kalmar, ... Brain 145 (2), 481-489, 2022 | 34 | 2022 |
Identification of expression quantitative trait loci associated with schizophrenia and affective disorders in normal brain tissue OG Bhalala, AP Nath, UK Brain Expression Consortium, M Inouye, ... PLoS genetics 14 (8), e1007607, 2018 | 34 | 2018 |
Regulation of gene expression through production of unstable mRNA isoforms CR Sibley Biochemical Society Transactions 42 (4), 1196-1205, 2014 | 33 | 2014 |