| Mutation of the mouse klotho gene leads to a syndrome resembling ageing M Kuro-o, Y Matsumura, H Aizawa, H Kawaguchi, T Suga, T Utsugi, ... nature 390 (6655), 45-51, 1997 | 4201 | 1997 |
| FGF23 induces left ventricular hypertrophy C Faul, AP Amaral, B Oskouei, MC Hu, A Sloan, T Isakova, OM Gutiérrez, ... The Journal of clinical investigation 121 (11), 2011 | 2285 | 2011 |
| Suppression of aging in mice by the hormone Klotho H Kurosu, M Yamamoto, JD Clark, JV Pastor, A Nandi, P Gurnani, ... Science 309 (5742), 1829-1833, 2005 | 2064 | 2005 |
| Regulation of fibroblast growth factor-23 signaling by klotho H Kurosu, Y Ogawa, M Miyoshi, M Yamamoto, A Nandi, KP Rosenblatt, ... Journal of Biological Chemistry 281 (10), 6120-6123, 2006 | 1606 | 2006 |
| The parathyroid is a target organ for FGF23 in rats IZ Ben-Dov, H Galitzer, V Lavi-Moshayoff, R Goetz, M Kuro-o, ... The Journal of clinical investigation 117 (12), 4003-4008, 2007 | 1223 | 2007 |
| Klotho deficiency causes vascular calcification in chronic kidney disease MC Hu, M Shi, J Zhang, H Quiñones, C Griffith, M Kuro-o, OW Moe Journal of the American Society of Nephrology 22 (1), 124-136, 2011 | 1208 | 2011 |
| Tissue-specific expression of βKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21 H Kurosu, M Choi, Y Ogawa, AS Dickson, R Goetz, AV Eliseenkova, ... Journal of Biological Chemistry 282 (37), 26687-26695, 2007 | 873 | 2007 |
| Identification of the humanklothogene and its two transcripts encoding membrane and secretedklothoprotein Y Matsumura, H Aizawa, T Shiraki-Iida, R Nagai, M Kuro-o, Y Nabeshima Biochemical and biophysical research communications 242 (3), 626-630, 1998 | 829 | 1998 |
| Regulation of Oxidative Stress by the Anti-aging Hormone Klotho*♦ M Yamamoto, JD Clark, JV Pastor, P Gurnani, A Nandi, H Kurosu, ... Journal of Biological Chemistry 280 (45), 38029-38034, 2005 | 814 | 2005 |
| Research resource: comprehensive expression atlas of the fibroblast growth factor system in adult mouse K Fon Tacer, AL Bookout, X Ding, H Kurosu, GB John, L Wang, R Goetz, ... Molecular endocrinology 24 (10), 2050-2064, 2010 | 764 | 2010 |
| βKlotho is required for metabolic activity of fibroblast growth factor 21 Y Ogawa, H Kurosu, M Yamamoto, A Nandi, KP Rosenblatt, R Goetz, ... Proceedings of the National Academy of Sciences 104 (18), 7432-7437, 2007 | 711 | 2007 |
| Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule MC Hu, M Shi, J Zhang, J Pastor, T Nakatani, B Lanske, MS Razzaque, ... The FASEB Journal 24 (9), 3438, 2010 | 688 | 2010 |
| Fibroblast growth factor 23 and Klotho: physiology and pathophysiology of an endocrine network of mineral metabolism MC Hu, K Shiizaki, M Kuro-o, OW Moe Annual review of physiology 75, 503-533, 2013 | 675 | 2013 |
| Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members R Goetz, A Beenken, OA Ibrahimi, J Kalinina, SK Olsen, AV Eliseenkova, ... Molecular and cellular biology 27 (9), 3417-3428, 2007 | 650 | 2007 |
| Klotho inhibits transforming growth factor-β1 (TGF-β1) signaling and suppresses renal fibrosis and cancer metastasis in mice S Doi, Y Zou, O Togao, JV Pastor, GB John, L Wang, K Shiizaki, ... Journal of Biological Chemistry 286 (10), 8655-8665, 2011 | 623 | 2011 |
| Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1 SK Cha, B Ortega, H Kurosu, KP Rosenblatt, M Kuro-o, CL Huang Proceedings of the National Academy of Sciences 105 (28), 9805-9810, 2008 | 492 | 2008 |
| The Klotho proteins in health and disease M Kuro-o Nature Reviews Nephrology 15 (1), 27-44, 2019 | 473 | 2019 |
| Klotho deficiency is an early biomarker of renal ischemia–reperfusion injury and its replacement is protective MC Hu, M Shi, J Zhang, H Quiñones, M Kuro-o, OW Moe Kidney international 78 (12), 1240-1251, 2010 | 446 | 2010 |
| Human smooth muscle myosin heavy chain isoforms as molecular markers for vascular development and atherosclerosis. M Aikawa, PN Sivam, M Kuro-o, K Kimura, KI Nakahara, SI Takewaki, ... Circulation research 73 (6), 1000-1012, 1993 | 417 | 1993 |
| Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation R Goetz, Y Nakada, MC Hu, H Kurosu, L Wang, T Nakatani, M Shi, ... Proceedings of the National Academy of Sciences 107 (1), 407-412, 2010 | 414 | 2010 |
